Pyruvic acid (PAMDB000102)

General function:

Involved in magnesium ion binding

Specific function:

2 pyruvate = 2-acetolactate + CO(2)

Gene Name:

ilvI

Locus Tag:

PA4696

Molecular weight:

63 kDa

Reactions

General function:

Involved in acetolactate synthase activity

Specific function:

2 pyruvate = 2-acetolactate + CO(2)

Gene Name:

ilvH

Locus Tag:

PA4695

Molecular weight:

17.8 kDa

Reactions

General function:

Involved in biosynthetic process

Specific function:

Chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate

Gene Name:

trpE

Locus Tag:

PA0609

Molecular weight:

54.6 kDa

Reactions

General function:

Involved in anthranilate phosphoribosyltransferase activity

Specific function:

Chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate

Gene Name:

trpD

Locus Tag:

PA0650

Molecular weight:

37.4 kDa

Reactions

General function:

Involved in D-serine ammonia-lyase activity

Specific function:

D-serine = pyruvate + NH(3)

Gene Name:

dsdA

Locus Tag:

PA3357

Molecular weight:

48.2 kDa

Reactions

General function:

Involved in catalytic activity

Specific function:

Catalyzes the formation of alpha-ketobutyrate from threonine in a two-step reaction. The first step is a dehydration of threonine, followed by rehydration and liberation of ammonia. Deaminates L-threonine, but also L-serine to a lesser extent

Gene Name:

ilvA

Locus Tag:

PA1326

Molecular weight:

55.9 kDa

Reactions

General function:

Involved in transferase activity, transferring acyl groups

Specific function:

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3)

Gene Name:

aceF

Locus Tag:

PA5016

Molecular weight:

56.7 kDa

Reactions

General function:

Involved in magnesium ion binding

Specific function:

Pyruvate + ferricytochrome b1 + H(2)O = acetate + CO(2) + ferrocytochrome b1

Gene Name:

poxB

Locus Tag:

PA5297

Molecular weight:

62.3 kDa

Reactions

General function:

Involved in protein-N(PI)-phosphohistidine-sugar phosphotransferase activity

Specific function:

The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylglucosamine transport

Gene Name:

nagE

Locus Tag:

PA3761

Molecular weight:

60.6 kDa

Reactions

General function:

Involved in D-amino-acid dehydrogenase activity

Specific function:

Oxidative deamination of D-amino acids

Gene Name:

dadA

Locus Tag:

PA5304

Molecular weight:

47.1 kDa

Reactions

General function:

Involved in catalytic activity

Specific function:

L-aspartate 4-semialdehyde + pyruvate = dihydrodipicolinate + 2 H(2)O

Gene Name:

dapA

Locus Tag:

PA1010

Molecular weight:

31.4 kDa

Reactions

General function:

Involved in catalytic activity

Specific function:

Interconversion of serine and glycine

Gene Name:

glyA

Locus Tag:

PA4602

Molecular weight:

45.2 kDa

Reactions

General function:

Involved in magnesium ion binding

Specific function:

ATP + pyruvate = ADP + phosphoenolpyruvate

Gene Name:

pykF

Locus Tag:

PA1498

Molecular weight:

51.5 kDa

Reactions

General function:

Involved in oxidoreductase activity

Specific function:

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3)

Gene Name:

aceE

Locus Tag:

PA5015

Molecular weight:

99.6 kDa

Reactions

General function:

Involved in L-serine ammonia-lyase activity

Specific function:

Deaminates also threonine, particularly when it is present in high concentration

Gene Name:

sdaA

Locus Tag:

PA2443

Molecular weight:

48.9 kDa

Reactions

General function:

Involved in sugar:hydrogen symporter activity

Specific function:

The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport

Gene Name:

fruA

Locus Tag:

PA3560

Molecular weight:

59 kDa

Reactions

General function:

Involved in magnesium ion binding

Specific function:

ATP + pyruvate = ADP + phosphoenolpyruvate

Gene Name:

pykA

Locus Tag:

PA4329

Molecular weight:

52.3 kDa

Reactions

General function:

Involved in catalytic activity

Specific function:

Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate

Gene Name:

ppsA

Locus Tag:

PA1770

Molecular weight:

85.8 kDa

Reactions

General function:

Involved in oxidoreductase activity

Specific function:

(S)-malate + NAD(+) = pyruvate + CO(2) + NADH

Gene Name:

sfcA

Locus Tag:

PA3471

Molecular weight:

62.4 kDa

Reactions

General function:

Involved in 4-amino-4-deoxychorismate lyase activity

Specific function:

Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate

Gene Name:

pabC

Locus Tag:

PA2964

Molecular weight:

29.9 kDa

Reactions

General function:

Involved in L-serine ammonia-lyase activity

Specific function:

Deaminates also threonine, particularly when it is present in high concentration

Gene Name:

sdaB

Locus Tag:

PA5379

Molecular weight:

49.2 kDa

Reactions

General function:

Involved in catalytic activity

Specific function:

(S)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c + 2 H(+)

Gene Name:

lldD

Locus Tag:

PA4771

Molecular weight:

41.1 kDa

Reactions

General function:

Involved in protein binding

Specific function:

Component of the phosphoenolpyruvate-dependent nitrogen- metabolic phosphotransferase system (nitrogen-metabolic PTS), that seems to be involved in regulating nitrogen metabolism. Enzyme I- Ntr transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (NPr). Could function in the transcriptional regulation of sigma-54 dependent operons in conjunction with the NPr (ptsO) and EIIA-Ntr (ptsN) proteins

Gene Name:

ptsP

Locus Tag:

PA0337

Molecular weight:

83.6 kDa

Reactions

General function:

Involved in sugar:hydrogen symporter activity

Specific function:

The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in galactitol transport

Gene Name:

gatB

Locus Tag:

PA4484

Molecular weight:

53.1 kDa

Reactions

General function:

Involved in oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

Specific function:

Fermentative lactate dehydrogenase

Gene Name:

ldhA

Locus Tag:

PA0927

Molecular weight:

35.8 kDa

Reactions

General function:

Involved in transporter activity

Specific function:

The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in galactitol transport

Gene Name:

gatA

Locus Tag:

PA4483

Molecular weight:

51.9 kDa

Reactions

General function:

Involved in lyase activity

Specific function:

Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. L-threo-phenylserine and L- erythro-phenylserine are also good substrates

Gene Name:

ltaE

Locus Tag:

PA0902

Molecular weight:

35.4 kDa

Reactions

General function:

Involved in carbon-carbon lyase activity

Specific function:

Catalyzes the reversible retro-aldol cleavage of 2-keto- 3-deoxy-L-rhamnonate (KDR) to pyruvate and lactaldehyde. 2-keto-3- deoxy-L-mannonate, 2-keto-3-deoxy-L-lyxonate and 4-hydroxy-2- ketoheptane-1,7-dioate (HKHD) are also reasonably good substrates, although 2-keto-3-deoxy-L-rhamnonate is likely to be the physiological substrate

Gene Name:

rhmA

Locus Tag:

PA4128

Molecular weight:

28.2 kDa

Reactions

General function:

Involved in oxidoreductase activity

Specific function:

(S)-malate + NADP(+) = pyruvate + CO(2) + NADPH

Gene Name:

maeB

Locus Tag:

PA5046

Molecular weight:

45.4 kDa

Reactions

General function:

Involved in 1-deoxy-D-xylulose-5-phosphate synthase activity

Specific function:

Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)

Gene Name:

dxs

Locus Tag:

PA4044

Molecular weight:

68 kDa

Reactions

General function:

Involved in catalytic activity

Specific function:

Catalyzes the formation of pyruvate and succinate from 2-methylisocitrate

Gene Name:

prpB

Locus Tag:

PA0796

Molecular weight:

32.1 kDa

Reactions

General function:

Involved in phosphoenolpyruvate-dependent sugar phosphotransferase system

Specific function:

The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in galactitol transport

Gene Name:

gatC

Locus Tag:

PA4482

Molecular weight:

10.5 kDa

General function:

Involved in 1-aminocyclopropane-1-carboxylate synthase activity

Specific function:

Specific function unknown

Gene Name:

yfbQ

Locus Tag:

PA2828

Molecular weight:

44.8 kDa

Reactions

General function:

Amino acid transport and metabolism

Specific function:

Specific function unknown

Gene Name:

yfdZ

Locus Tag:

PA4715

Molecular weight:

46.1 kDa

Reactions