Identification
Name: Galactitol-specific phosphotransferase enzyme IIB component
Synonyms:
  • EIIB-Gat
  • PTS system galactitol-specific EIIB component
Gene Name: gatB
Enzyme Class:
Biological Properties
General Function: Involved in sugar:hydrogen symporter activity
Specific Function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in galactitol transport
Cellular Location: Cytoplasm (Potential)
KEGG Pathways:
KEGG Reactions:
Thumb+Protein N(pi)-phospho-L-histidineThumb+Protein histidine
Galactitol + Protein N(pi)-phospho-L-histidine ↔ Galactitol 1-phosphate + Protein histidine
ReactionCard
Protein N(pi)-phospho-L-histidine+SugarProtein histidine+Thumb
Protein N(pi)-phospho-L-histidine + Sugar ↔ Protein histidine + Sugar phosphate
ReactionCard
SMPDB Reactions:
Thumb+HPr - phosphorylatedGalactose 1-phosphate+HPr+Thumb
Galactitol + HPr - phosphorylated → Galactose 1-phosphate + HPr + Galactose 1-phosphate
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb+ThumbThumb+Thumb
Complex Reactions:
Protein EIIB N(pi)-phospho-L-histidine/cysteine+Thumbprotein EIIB+sugar phosphate
Protein EIIB N(pi)-phospho-L-histidine/cysteine + Sucrose → protein EIIB + sugar phosphate
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000040GalactitolMetaboCard
PAMDB000996Galactitol 1-phosphateMetaboCard
PAMDB000556Galactose 1-phosphateMetaboCard
PAMDB000111Phosphoenolpyruvic acidMetaboCard
PAMDB000102Pyruvic acidMetaboCard
PAMDB000109SucroseMetaboCard
GO Classification:
Function
carbohydrate transmembrane transporter activity
cation transmembrane transporter activity
cation:sugar symporter activity
ion transmembrane transporter activity
protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
solute:cation symporter activity
substrate-specific transmembrane transporter activity
sugar:hydrogen symporter activity
transmembrane transporter activity
transporter activity
Process
carbohydrate transport
establishment of localization
phosphoenolpyruvate-dependent sugar phosphotransferase system
transport
Gene Properties
Locus tag: PA4484
Strand: +
Entrez Gene ID: 881181
Accession: NP_253174.1
GI: 15599680
Sequence start: 5015535
Sequence End: 5016980
Sequence Length: 1445
Gene Sequence:
>PA4484
ATGCAATGGGAAACCGTGATCGGGCTGGAAATCCACGCACAGCTCGCCACCCAATCGAAGATCTTCTCCGGCAGCTCGACCGCCTTCGGCGCCGCGCCGAATACCCAAGCCAGCCTGGTCGACCTGGCCATGCCGGGCACCCTGCCGGTGCTCAACGAGGAGGCCGTACGCATGGCCTGCCTGTTCGGCCTGGCGATCGACGCACGGATCGACCGGCAGAACGTGTTCGCCCGCAAGAACTACTTCTACCCCGACCTGCCGAAGGGCTACCAGACCAGCCAGATGGACCATCCTATCGTCGGCAAGGGCCATCTCGACATCACCCTGGAAGACGGCACCACCAAGCGCATCGGCATCACCCGCGCGCACCTGGAGGAGGACGCCGGCAAGAGCCTGCACGAAGACTTCCAGGGCATGAGCGGCATCGACCTGAACCGCGCCGGCACGCCGTTGCTGGAGATCGTTTCCGAGCCGGACATCCGCAGCGCCAAGGAAGCCGTGGCCTACGTCAAGGCGATCCACGCCCTGGTGCGCTACCTGGGCATCTGCGACGGCAACATGGCCGAGGGCTCGCTGCGCTGCGACTGCAACGTCTCGGTACGACCGAAGGGCCAGGCCGAATTCGGCACCCGCGCCGAGATCAAGAACGTCAACTCCTTCCGCTTCATCGAGAAGGCGATCAACCACGAGATCCAGCGCCAGATCGAGCTGATCGAGGACGGCGGCAAGGTAGTCCAGGAAACCCGCCTGTACGACCCGAACAAGGACGAGACCCGCTCCATGCGCGGCAAGGAAGAAGCCAACGACTACCGTTACTTCCCCTGTCCCGACCTGCTGCCGGTGGTCATCGAGCCCGAGTACCTGGCGAAGCTGCGCGAGCAACTGCCGGAACTGCCGGTGCAGAAGCGCGAACGCTTCGAGAGCCAGTACGGCCTGTCCGCCTACGATGCCAGCGTGCTGTCCGCCAGCCGCGAGATGGCCGACTACTTCGAGAAGGTCCAGGGCATCTGCGGCGACGCCAAGCTGGCGGCCAACTGGGTGATGGTCGAGCTGGGCAGCCTGCTCAACAAGGACGGCCTGGAGATCGAGCAGTCCCCGGTGTCCGCCGAGCAACTGGGCGGCATGATCCTGCGCATCAAGGACAACACCATCTCCGGCAAGCTCGCCAAGATGGTCTTCGAAGCCATGGCCAACGGCGAGGGTTCCGCCGACCAGATCATCGAGGCCAAGGGCCTGAAGCAGGTCACCGACAGTGGCGCCATCGAGAAGATGCTCGACGAGGTGCTGGCGGCCAACGCCGAGCAGGTCGAGCAGTACCGCGCTGCCGACGAGGCCAAGCGCGGCAAGATGTTCGGCTTCTTCGTCGGCCAGGCGATGAAGGCCTCGAAAGGCAAGGCCAACCCGCAGCAGGTGAACGAGTTGCTGAAGAAAAAGCTCGAAGCGTGA
Protein Properties
Protein Residues: 481
Protein Molecular Weight: 53.1 kDa
Protein Theoretical pI: 5.05
Hydropathicity (GRAVY score): -0.347
Charge at pH 7 (predicted): -11.47
Protein Sequence:
>PA4484
MQWETVIGLEIHAQLATQSKIFSGSSTAFGAAPNTQASLVDLAMPGTLPVLNEEAVRMACLFGLAIDARIDRQNVFARKNYFYPDLPKGYQTSQMDHPIVGKGHLDITLEDGTTKRIGITRAHLEEDAGKSLHEDFQGMSGIDLNRAGTPLLEIVSEPDIRSAKEAVAYVKAIHALVRYLGICDGNMAEGSLRCDCNVSVRPKGQAEFGTRAEIKNVNSFRFIEKAINHEIQRQIELIEDGGKVVQETRLYDPNKDETRSMRGKEEANDYRYFPCPDLLPVVIEPEYLAKLREQLPELPVQKRERFESQYGLSAYDASVLSASREMADYFEKVQGICGDAKLAANWVMVELGSLLNKDGLEIEQSPVSAEQLGGMILRIKDNTISGKLAKMVFEAMANGEGSADQIIEAKGLKQVTDSGAIEKMLDEVLAANAEQVEQYRAADEAKRGKMFGFFVGQAMKASKGKANPQQVNELLKKKLEA
References
External Links:
Resource Link
Genome ID: PA4484
Entrez Gene ID: 881181
NCBI Protein ID: 15599680
General Reference: PaperBLAST - Find papers about PA4484 and its homologs