L-lactate dehydrogenase [cytochrome] (PA4771)

Identification
Name: L-lactate dehydrogenase [cytochrome]
Synonyms: Not Available
Gene Name: lldD
Enzyme Class:
Biological Properties
General Function: Involved in catalytic activity
Specific Function: (S)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c + 2 H(+)
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb+2 Ferricytochrome c+Thumb ↔ Thumb+2 Ferrocytochrome c+2 Thumb+Thumb
L-Lactic acid + 2 Ferricytochrome c + Ferricytochrome c ↔ Pyruvic acid + 2 Ferrocytochrome c + 2 Hydrogen ion + Ferrocytochrome c
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SMPDB Reactions:
L-Lactic acid+oxidized electron acceptor+Thumb → Reduced acceptor+Thumb
L-Lactic acid + oxidized electron acceptor + L-Lactic acid → Reduced acceptor + Pyruvic acid
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Thumb+oxidized electron acceptor → Thumb+reduced electron acceptor
L-Lactic acid + oxidized electron acceptor → Pyruvic acid + reduced electron acceptor
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PseudoCyc/BioCyc Reactions:
an oxidized electron acceptor+Thumb → a reduced electron acceptor+Thumb
an oxidized electron acceptor + L-Lactic acid → a reduced electron acceptor + Pyruvic acid
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Complex Reactions:
Thumb+Thumb → Thumb+Thumb
L-Lactic acid + Ubiquinone-8 → Pyruvic acid + Ubiquinol-8
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Thumb+Menaquinone 8 → Thumb+Thumb
L-Lactic acid + Menaquinone 8 → Menaquinol 8 + Pyruvic acid
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Thumb+2 Thumb → Thumb+2 Thumb+2 Thumb
L-Lactic acid + 2 Ferricytochrome c → Pyruvic acid + 2 Ferrocytochrome c + 2 Hydrogen ion
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Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB002046Ferricytochrome cMetaboCard
PAMDB003525Ferrocytochrome cMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000079L-Lactic acidMetaboCard
PAMDB001653Menaquinol 8MetaboCard
PAMDB000102Pyruvic acidMetaboCard
PAMDB000237Ubiquinol-8MetaboCard
PAMDB001700Ubiquinone-8MetaboCard
GO Classification:
Function
binding
catalytic activity
FMN binding
L-lactate dehydrogenase (cytochrome) activity
lactate dehydrogenase activity
nucleotide binding
oxidoreductase activity
oxidoreductase activity, acting on CH-OH group of donors
Process
carboxylic acid metabolic process
cellular metabolic process
lactate metabolic process
metabolic process
monocarboxylic acid metabolic process
organic acid metabolic process
oxidation reduction
oxoacid metabolic process
Gene Properties
Locus tag: PA4771
Strand: +
Entrez Gene ID: 881809
Accession: NP_253459.1
GI: 15599965
Sequence start: 5357230
Sequence End: 5358375
Sequence Length: 1145
Gene Sequence: 
>PA4771
ATGATCATTTCCGCTTCCACCGACTACCGCGCCGCCGCCCAACGCAAGCTGCCGCCGTTCCTCTTCCACTACATCGACGGCGGCGCCTACGCCGAGTACACCCTGCGCCGCAACGTCGAGGACCTGTCGGCCATCGCCCTGCGTCAGCGGGTGCTGAAGAACATGTCCGAGCTGAGCCTGGAAACCCGCCTGTTCGACGAGACCCTGGCGATGCCGGTGGCGCTCGCCCCGGTCGGTCTCACCGGCATGTACGCCCGCCGCGGCGAGGTCCAGGCGGCGCGCGCGGCGGCGGCGAAGGGCGTGCCCTTCACCCTGTCGACGGTATCGGTGTGCCCGATTGAGGAGGTCGCCCCGGCCATCGACCGGCCGATGTGGTTCCAGCTCTACGTGCTGAAGGACCGCGGCTTCATGCGCAACGCCCTGGAGCGGGCCAAGGCCGCCGGCGTCACCACCCTGGTGTTCACCGTCGACATGCCGGTCCCCGGCGCCCGCTACCGCGACGCCCATTCCGGCATGAGCGGCCCCTACGCCGCGCCGCGCCGCATCCTGCAAGCCATGACCCACCCGGCCTGGGCCTGGGACGTCGGCCTGCTGGGCAAGCCCCACGACCTCGGCAACATTTCCGCCTACCGCGGCAACCCGACCGGACTGGAGGACTACATCGGCTGGCTGGGCGCCAACTTCGACCCGTCGATTTCCTGGAAGGACCTGGAGTGGATCCGCGAGTTCTGGGACGGCCCGATGGTGATCAAGGGCATCCTCGACCCGGAGGATGCCAGGGATGCGGTGAAGTTCGGCGCCGACGGCATCGTCGTCTCCAACCACGGCGGGCGCCAGCTCGACGGCGTGCTGTCCAGCGCCCGCGCGCTGCCGGCGATAGCCGATGCGGTGAAGGGTGAACTGGCGATCCTTGCCGACTCCGGCATCCGCACCGGTCTCGACGTGGTGCGGATGATCGCCCTCGGCGCCGACAGCGTGCTGCTCGGCCGCGCCTTCGTCTACGCCCTGGCCGCCGCCGGCGAGGCCGGGGTGCGCAACCTGCTCGAACTGATCGAAAAGGAAATGCGCGTGGCCATGGTCCTCACCGGGGCCAAGTCGATCGGCGAGATCAGCGCCGACTCGCTGGTCCGCGAACTGGGCGCCTGA
Protein Properties
Protein Residues: 381
Protein Molecular Weight: 41.1 kDa
Protein Theoretical pI: 6.38
Hydropathicity (GRAVY score): 0.11
Charge at pH 7 (predicted): -1.82
Protein Sequence: 
>PA4771
MIISASTDYRAAAQRKLPPFLFHYIDGGAYAEYTLRRNVEDLSAIALRQRVLKNMSELSLETRLFDETLAMPVALAPVGLTGMYARRGEVQAARAAAAKGVPFTLSTVSVCPIEEVAPAIDRPMWFQLYVLKDRGFMRNALERAKAAGVTTLVFTVDMPVPGARYRDAHSGMSGPYAAPRRILQAMTHPAWAWDVGLLGKPHDLGNISAYRGNPTGLEDYIGWLGANFDPSISWKDLEWIREFWDGPMVIKGILDPEDARDAVKFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGELAILADSGIRTGLDVVRMIALGADSVLLGRAFVYALAAAGEAGVRNLLELIEKEMRVAMVLTGAKSIGEISADSLVRELGA
References
External Links:
Resource Link
Genome ID: PA4771
Entrez Gene ID: 881809
NCBI Protein ID: 15599965
General Reference: PaperBLAST - Find papers about PA4771 and its homologs