Aminodeoxychorismate lyase (PA2964)

Identification
Name: Aminodeoxychorismate lyase
Synonyms:
  • 4-amino-4-deoxychorismate lyase
  • ADC lyase
  • ADCL
Gene Name: pabC
Enzyme Class:
Biological Properties
General Function: Involved in 4-amino-4-deoxychorismate lyase activity
Specific Function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb ↔ Thumb+Thumb+Thumb
4-Amino-4-deoxychorismate ↔ p-Aminobenzoic acid + Hydrogen ion + Pyruvic acid
ReactionCard
Thumb ↔ Thumb+Thumb
4-Amino-4-deoxychorismate ↔ p-Aminobenzoic acid + Pyruvic acid
ReactionCard
SMPDB Reactions:
4-amino-4-deoxychorismate+Thumb → Thumb+Thumb+Thumb
4-amino-4-deoxychorismate + 4-Amino-4-deoxychorismate → Pyruvic acid + Hydrogen ion + p-Aminobenzoic acid
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb ↔ Thumb+Thumb+Thumb
4-Amino-4-deoxychorismate ↔ p-Aminobenzoic acid + Hydrogen ion + Pyruvic acid
ReactionCard
Complex Reactions:
Thumb → Thumb+Thumb
4-Amino-4-deoxychorismate → p-Aminobenzoic acid + Pyruvic acid
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB0009334-Amino-4-deoxychorismateMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000367p-Aminobenzoic acidMetaboCard
PAMDB000102Pyruvic acidMetaboCard
GO Classification:
Function
4-amino-4-deoxychorismate lyase activity
binding
carbon-carbon lyase activity
catalytic activity
cofactor binding
lyase activity
oxo-acid-lyase activity
pyridoxal phosphate binding
Process
cellular amino acid and derivative metabolic process
cellular amino acid biosynthetic process
cellular amino acid metabolic process
cellular metabolic process
folic acid biosynthetic process
metabolic process
Gene Properties
Locus tag: PA2964
Strand: -
Entrez Gene ID: 880488
Accession: NP_251654.1
GI: 15598160
Sequence start: 3322759
Sequence End: 3323574
Sequence Length: 815
Gene Sequence: 
>PA2964
ATGCTGGACTGGGTCGACGGCCGGCCCGCCGCCGAGCTGTCCGTGCGCGATCGCGGACTGGCCTATGGCGACGGGCTGTTCGAGACCCTGGCGGTGCGCGCCGGCACGCCGCGTCTCCTGGAGCGCCACCTGGCGCGCCTGGAAGAGGGGTGTCGGCGCCTGGCGATCCCTCTCGACACCGCGGCGTTGCGCCAGGAGTTGCTGGCGTTCTGCGCGGCTCTGGGCGACGGTGTCGCCAAGCTGATCGTCACCCGCGGCGAGGGTTTGCGTGGCTACGCGCCGCCTGCCGAGGCCTCGCCGCGGCGAATCCTCTCCGGATCGCCGCGTCCGGCCTATCCCGAGCGCCACTGGCAGCAAGGCGTGCGCCTGTTCGCTTGCCGCACGCGCCTGGCCGAGCAGCCCCTGCTGGCCGGCCTCAAGCACCTCAATCGCCTGGAGCAGGTCCTCGCCCGTGCCGAGTGGAGCGACGCCGGGCATGCCGAAGGGCTCATGCTGGACGTGCACGAGCGGGTAGTGGAGGGCGTGTTCAGCAACCTGCTGCTGGTTCTCGACGGCACCCTCGTGGCGCCTGACCTGCGGCGCTGCGGCGTCGCTGGAGTGATGCGCGCGGAATTGCTCGAGCGCGCCGAAGGAATCGGCGTCCCGCTGGCGATACGGGATGTTTCCATGGCTGAACTGGCGACGGCCGACGAGGTCTTTCTGTGCAACAGCCAGTTCGGCATCTGGCCGGTCCGGGCATTGGACGAGCACGTCTGGCCGGTCGGCGAGCTGACCCGTAAACTGCAAGACCAACTTCGCGACGACCTGGATTTCTGA
Protein Properties
Protein Residues: 271
Protein Molecular Weight: 29.9 kDa
Protein Theoretical pI: 5.7
Hydropathicity (GRAVY score): -0.044
Charge at pH 7 (predicted): -4.7
Protein Sequence: 
>PA2964
MLDWVDGRPAAELSVRDRGLAYGDGLFETLAVRAGTPRLLERHLARLEEGCRRLAIPLDTAALRQELLAFCAALGDGVAKLIVTRGEGLRGYAPPAEASPRRILSGSPRPAYPERHWQQGVRLFACRTRLAEQPLLAGLKHLNRLEQVLARAEWSDAGHAEGLMLDVHERVVEGVFSNLLLVLDGTLVAPDLRRCGVAGVMRAELLERAEGIGVPLAIRDVSMAELATADEVFLCNSQFGIWPVRALDEHVWPVGELTRKLQDQLRDDLDF
References
External Links:
Resource Link
Genome ID: PA2964
Entrez Gene ID: 880488
NCBI Protein ID: 15598160
General Reference: PaperBLAST - Find papers about PA2964 and its homologs