Identification
Name: D-amino acid dehydrogenase small subunit
Synonyms: Not Available
Gene Name: dadA
Enzyme Class:
Biological Properties
General Function: Involved in D-amino-acid dehydrogenase activity
Specific Function: Oxidative deamination of D-amino acids
Cellular Location: Cell inner membrane; Peripheral membrane protein
KEGG Pathways:
KEGG Reactions:
alpha-Amino acid+Thumb+Acceptor2-Oxo acid+Thumb+Reduced acceptor
alpha-Amino acid + Water + Acceptor ↔ 2-Oxo acid + Ammonia + Reduced acceptor
ReactionCard
Thumb+Thumb+AcceptorThumb+Thumb+Reduced acceptor
D-Phenylalanine + Water + Acceptor ↔ Phenylpyruvic acid + Ammonia + Reduced acceptor
ReactionCard
D-Amino acid+Thumb+Acceptor2-Oxo acid+Thumb+Reduced acceptor
D-Amino acid + Water + Acceptor ↔ 2-Oxo acid + Ammonia + Reduced acceptor
ReactionCard
SMPDB Reactions:
Thumb+Thumb+ThumbThumb+Thumb+Thumb
Thumb+Thumb+cytochrome c nitrite reductaseThumb+Thumb+cytochrome c nitrite reductase
Phenylpyruvic acid + Ammonia + cytochrome c nitrite reductase ↔ D-Phenylalanine + Water + cytochrome c nitrite reductase
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Thumb+Thumb+an electron-transfer quinoneThumb+Thumb+electron-transfer quinol
D-Alanine + Water + an electron-transfer quinone → Ammonium + Pyruvic acid + electron-transfer quinol
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PseudoCyc/BioCyc Reactions:
Thumb+Thumb+ThumbThumb+Thumb+Thumb
alpha-Amino acid+Thumb+Acceptor2-Oxo acid+Thumb+Reduced acceptor
alpha-Amino acid + Water + Acceptor ↔ 2-Oxo acid + Ammonia + Reduced acceptor
ReactionCard
Thumb+Thumb+AcceptorThumb+Thumb+Reduced acceptor
D-Phenylalanine + Water + Acceptor ↔ Phenylpyruvic acid + Ammonia + Reduced acceptor
ReactionCard
A D-amino acid+Thumb+acceptora 2-oxo acid+Thumb+reduced acceptor
A D-amino acid + Water + acceptor → a 2-oxo acid + Ammonia + reduced acceptor
ReactionCard
D-Amino acid+Thumb+Acceptor2-Oxo acid+Thumb+Reduced acceptor
D-Amino acid + Water + Acceptor ↔ 2-Oxo acid + Ammonia + Reduced acceptor
ReactionCard
Thumb+Thumb+ThumbThumb+Thumb+Thumb
Thumb+Thumb+cytochrome c nitrite reductaseThumb+Thumb+cytochrome c nitrite reductase
Phenylpyruvic acid + Ammonia + cytochrome c nitrite reductase ↔ D-Phenylalanine + Water + cytochrome c nitrite reductase
ReactionCard
Thumb+Thumb+an electron-transfer quinoneThumb+Thumb+electron-transfer quinol
D-Alanine + Water + an electron-transfer quinone → Ammonium + Pyruvic acid + electron-transfer quinol
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Thumb
D-arginine + an oxidized unknown electron acceptor + H2O = 5-guanidino-2-oxo-pentanoate + ammonium + an reduced unknown electron acceptor
ReactionCard
Thumb
D-arginine + an oxidized unknown electron acceptor → iminoarginine + an reduced unknown electron acceptor
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D-Amino-Acids+PAMDB000142+Acceptor2-Oxo-carboxylates+PAMDB001595+Donor-H2
D-Amino-Acids + Water + Acceptor → 2-Oxo-carboxylates + Ammonium + Donor-H2
ReactionCard
Complex Reactions:
Thumb+Thumb+ThumbThumb+Thumb+Thumb
A D-amino acid+Thumb+acceptora 2-oxo acid+Thumb+reduced acceptor
A D-amino acid + Water + acceptor → a 2-oxo acid + Ammonia + reduced acceptor
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000017AmmoniaMetaboCard
PAMDB001595AmmoniumMetaboCard
PAMDB000333D-AlanineMetaboCard
PAMDB000992D-PhenylalanineMetaboCard
PAMDB000308FADMetaboCard
PAMDB000293FADH2MetaboCard
PAMDB000459HydroquinoneMetaboCard
PAMDB000084Phenylpyruvic acidMetaboCard
PAMDB000102Pyruvic acidMetaboCard
PAMDB003450QuinoneMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Function
catalytic activity
oxidoreductase activity
Gene Properties
Locus tag: PA5304
Strand: -
Entrez Gene ID: 878057
Accession: NP_253991.1
GI: 15600497
Sequence start: 5972178
Sequence End: 5973476
Sequence Length: 1298
Gene Sequence:
>PA5304
ATGCGAGTTCTGGTCCTTGGCAGCGGTGTCATCGGTACCGCCAGTGCGTATTACCTGGCCCGTGCCGGGTTCGAGGTGGTGGTGGTCGACCGTCAGGACGGTCCCGCGCTGGAAACCAGCTTCGCCAACGCCGGCCAGGTGTCTCCCGGCTACGCTTCGCCCTGGGCAGCCCCGGGCATTCCCCTGAAGGCCATGAAGTGGCTGCTGGAAAAGCACGCGCCGCTGGCCATCAAGCTCACCTCCGATCCCAGCCAGTACGCCTGGATGCTGCAGATGCTGCGCAACTGCACCGCCGAGCGCTACGCCGTGAACAAGGAGCGCATGGTCCGCCTGTCCGAGTACAGCCGCGATTGCCTCGACGAACTGCGCGCCGAGACCGGCATCGCCTACGAGGGCCGCACCCTCGGCACCACCCAACTGTTCCGCACCCAGGCGCAGCTGGACGCCGCCGGCAAGGACATCGCCGTGCTCGAGCGCTCCGGCGTGCCCTACGAGGTTCTCGACCGCGACGGCATCGCCCGCGTAGAGCCGGCTTTGGCCAAGGTCGCCGACAAGCTGGTCGGCGCCTTGCGCCTGCCCAACGACCAGACCGGCGACTGCCAGCTGTTCACCACCCGCCTGGCGGAAATGGCCAAGGGCCTGGGCGTGGAGTTCCGCTTCGGCCAGAACATCGAGCGCCTGGACTTCGCCGGCGACCGCATCAACGGCGTGCTGGTCAACGGCGAATTGCTCACCGCCGACCACTACGTGCTGGCCCTGGGCAGCTACTCGCCGCAACTGCTCAAGCCGCTGGGTATCAAGGCTCCGGTCTATCCGCTGAAGGGTTATTCGCTGACCGTGCCGATCACCAACCCGGAGATGGCGCCGACCTCGACCATCCTCGACGAGACCTACAAGGTGGCGATCACCCGCTTCGACCAGCGCATCCGCGTCGGCGGCATGGCGGAAATCGCCGGCTTCGACCTGTCGCTGAACCCGCGCCGCCGCGAGACCCTGGAAATGATCACCACCGACCTCTATCCCGAGGGCGGCGATATCAGCCAGGCGACCTTCTGGACCGGCCTGCGCCCGGCGACCCCGGATGGCACCCCGATCGTCGGCGCCACCCGCTACCGCAACCTGTTCCTCAATACCGGCCACGGCACCCTGGGTTGGACCATGGCCTGCGGGTCGGGTCGCTACCTGGCCGACCTGATGGCGAAGAAGCGCCCGCAGATCAGTACCGAAGGCCTGGATATTTCCCGCTACAGCAATTCCCCGGAGAACGCCAAGAATGCCCATCCAGCGCCAGCACACTAA
Protein Properties
Protein Residues: 432
Protein Molecular Weight: 47.1 kDa
Protein Theoretical pI: 7.49
Hydropathicity (GRAVY score): -0.184
Charge at pH 7 (predicted): 1.09
Protein Sequence:
>PA5304
MRVLVLGSGVIGTASAYYLARAGFEVVVVDRQDGPALETSFANAGQVSPGYASPWAAPGIPLKAMKWLLEKHAPLAIKLTSDPSQYAWMLQMLRNCTAERYAVNKERMVRLSEYSRDCLDELRAETGIAYEGRTLGTTQLFRTQAQLDAAGKDIAVLERSGVPYEVLDRDGIARVEPALAKVADKLVGALRLPNDQTGDCQLFTTRLAEMAKGLGVEFRFGQNIERLDFAGDRINGVLVNGELLTADHYVLALGSYSPQLLKPLGIKAPVYPLKGYSLTVPITNPEMAPTSTILDETYKVAITRFDQRIRVGGMAEIAGFDLSLNPRRRETLEMITTDLYPEGGDISQATFWTGLRPATPDGTPIVGATRYRNLFLNTGHGTLGWTMACGSGRYLADLMAKKRPQISTEGLDISRYSNSPENAKNAHPAPAH
References
External Links:
Resource Link
Genome ID: PA5304
Entrez Gene ID: 878057
NCBI Protein ID: 15600497
General Reference: PaperBLAST - Find papers about PA5304 and its homologs