Identification
Name: NADP-dependent malic enzyme
Synonyms:
  • NADP-ME
Gene Name: maeB
Enzyme Class:
Biological Properties
General Function: Involved in oxidoreductase activity
Specific Function: (S)-malate + NADP(+) = pyruvate + CO(2) + NADPH
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb+ThumbThumb+Thumb+Thumb
Thumb+ThumbThumb+Thumb+Thumb+Thumb
Thumb+Thumb+ThumbThumb+Thumb+Thumb
SMPDB Reactions:
L-Malic acid+Thumb+ThumbThumb+NADPH+Thumb+Thumb
PseudoCyc/BioCyc Reactions:
Thumb+ThumbThumb+Thumb+Thumb
Thumb+ThumbThumb+Thumb+Thumb+Thumb
Complex Reactions:
Thumb+ThumbThumb+Thumb+Thumb
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000568Carbon dioxideMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000058L-Malic acidMetaboCard
PAMDB000089NADPMetaboCard
PAMDB000615NADPHMetaboCard
PAMDB000102Pyruvic acidMetaboCard
GO Classification:
Function
acyltransferase activity
binding
catalytic activity
cation binding
ion binding
metal ion binding
NAD or NADH binding
nucleotide binding
oxidoreductase activity
oxidoreductase activity, acting on CH-OH group of donors
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
transferase activity
transferase activity, transferring acyl groups
transferase activity, transferring acyl groups other than amino-acyl groups
Process
metabolic process
oxidation reduction
Gene Properties
Locus tag: PA5046
Strand: -
Entrez Gene ID: 881142
Accession: NP_253733.1
GI: 15600239
Sequence start: 5683471
Sequence End: 5684739
Sequence Length: 1268
Gene Sequence:
>PA5046
ATGTCCGATCTTAAAACCGCTGCCCTCGAATATCACGCACAACCCCGTCCGGGAAAACTGAGTGTCGAGCTGACCAAACCCACCGCTACCGCCCGGGACCTGTCCCTGGCCTACAGCCCGGGTGTCGCCGAGCCGGTGCGTGAAATCGCCCGCGATGCCGAGCTGGCCTACCAGTACACCGGCAAGGGCAACCTGGTGGCAGTGATTTCCGACGGCACCGCGATTCTCGGCCTGGGTAACCTCGGCCCGCTGGCCTCCAAGCCGGTGATGGAAGGCAAGGGTGTGCTGTTCAAGCGCTTCGCCGGCATCGACGTGTTCGACATCGAGGTCGACGCCGAGAGCCCGCAGGCTTTCATCGATACCGTCAAGCGTATTTCCATCACCTTCGGCGGTATCAACCTCGAGGACATCAAGGCTCCCGAGTGTTTCGAGATCGAGCGCGCGCTGATCGAACAGTGCGACATCCCGGTGTTCCACGATGACCAGCACGGCACCGCCATCGTGACCGCGGCGGGCATGCTCAACGCGCTGGAACTGGCCGGCAAGAAGCTGGAAGAAGCGAAGATCGTCTGCCTCGGCGCCGGCGCTGCCGCCATCTCCTGCATGAAGCTGCTGGTGAGCATGGGCGCCAAGGTCGAGAACATCTACATGATCGACCGCAAGGGCGTGATCCACGCCGGTCGCGACGATCTGAACCAGTACAAGTCGGTGTTCGCCACCGAGACCGACAAGCGCACCCTGGCCGACGCCCTGGAGGGCGCCGACGTGTTCGTCGGCCTGTCCGGCGCCAACCTGCTGGAGCCGGAAGACCTCAAGCGCATGGCGCCGAACCCGATCGTGTTCGCCTGCTCGAACCCGGACCCGGAGATCAAGCCGGAACTGGCCCATGCCACCCGTAACGACGTGATCATGGCTACCGGTCGTTCCGACTATCCGAATCAGGTCAACAACGTGCTCGGTTTCCCCTTCATCTTCCGTGGTGCCCTGGACGTACGTGCCACGCGCATCAACGAAGAGATGAAGATCGCCGCCGCCCTGGCCCTGCGCGACCTGGCCAAGCAGCCGGTCCCGGAAGACGTCTGCGCCGCCTATGGCGTGGACAAGCTGGAATTCGGCCGCGAGTACATCATTCCGAAGCCGATGGACAAGCGCCTGATCACCGTGGTCTCCGATGCCGTGGCCAAGGCTGCCATCGAGACCGGCGTGGCTACCCTGCCGTATCCGAAGAACTATCCGCTGAAATCGGTGGACGACGTCTTCAACGGCTGA
Protein Properties
Protein Residues: 422
Protein Molecular Weight: 45.4 kDa
Protein Theoretical pI: 4.81
Hydropathicity (GRAVY score): 0.001
Charge at pH 7 (predicted): -11.96
Protein Sequence:
>PA5046
MSDLKTAALEYHAQPRPGKLSVELTKPTATARDLSLAYSPGVAEPVREIARDAELAYQYTGKGNLVAVISDGTAILGLGNLGPLASKPVMEGKGVLFKRFAGIDVFDIEVDAESPQAFIDTVKRISITFGGINLEDIKAPECFEIERALIEQCDIPVFHDDQHGTAIVTAAGMLNALELAGKKLEEAKIVCLGAGAAAISCMKLLVSMGAKVENIYMIDRKGVIHAGRDDLNQYKSVFATETDKRTLADALEGADVFVGLSGANLLEPEDLKRMAPNPIVFACSNPDPEIKPELAHATRNDVIMATGRSDYPNQVNNVLGFPFIFRGALDVRATRINEEMKIAAALALRDLAKQPVPEDVCAAYGVDKLEFGREYIIPKPMDKRLITVVSDAVAKAAIETGVATLPYPKNYPLKSVDDVFNG
References
External Links:
Resource Link
Genome ID: PA5046
Entrez Gene ID: 881142
NCBI Protein ID: 15600239
General Reference: PaperBLAST - Find papers about PA5046 and its homologs