D-lactate dehydrogenase_ (PA0927)

Identification
Name: D-lactate dehydrogenase_
Synonyms:
  • D-LDH
  • Fermentative lactate dehydrogenase
Gene Name: ldhA
Enzyme Class:
Biological Properties
General Function: Involved in oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Specific Function: Fermentative lactate dehydrogenase
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb ↔ Thumb+Thumb+Thumb
D-Lactic acid + NAD ↔ Hydrogen ion + NADH + Pyruvic acid
ReactionCard
Thumb+Thumb ↔ Thumb+Thumb+Thumb
D-Lactic acid + NAD ↔ Pyruvic acid + NADH + Hydrogen ion
ReactionCard
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb+Thumb ↔ Thumb+Thumb+Thumb
D-Lactic acid + NAD ↔ Hydrogen ion + NADH + Pyruvic acid
ReactionCard
Thumb+Thumb ← Thumb+Thumb+Thumb
NAD + D-Lactic acid ← Hydrogen ion + NADH + Pyruvic acid
ReactionCard
Complex Reactions:
Thumb+Thumb → Thumb+Thumb
D-Lactic acid + NAD → Pyruvic acid + NADH
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000334D-Lactic acidMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000197NADMetaboCard
PAMDB000398NADHMetaboCard
PAMDB000102Pyruvic acidMetaboCard
GO Classification:
Function
binding
catalytic activity
cofactor binding
NAD or NADH binding
nucleotide binding
oxidoreductase activity
oxidoreductase activity, acting on CH-OH group of donors
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Process
metabolic process
Gene Properties
Locus tag: PA0927
Strand: -
Entrez Gene ID: 881895
Accession: NP_249618.1
GI: 15596124
Sequence start: 1011983
Sequence End: 1012972
Sequence Length: 989
Gene Sequence: 
>PA0927
ATGCGCATCCTGTTCTTCAGCAGCCAGGCCTACGACAGCGAGAGCTTCCAGGCCAGCAACCACCGGCACGGCTTCGAACTGCACTTCCAGCAGGCCCACCTGCAGGCGGACACGGCGGTCCTCGCCCAGGGCTTCGAAGTAGTCTGCGCCTTCGTCAACGACGACCTCTCGCGGCCGGTGCTGGAACGCCTGGCGGCCGGCGGCACGCGCCTGGTCGCCCTGCGCTCGGCCGGCTACAACCACGTCGACCTGGCCGCCGCCGAAGCGCTCGGCCTGCCGGTGGTGCACGTCCCGGCCTATTCGCCGCACGCTGTCGCCGAGCACGCGGTCGGCCTGATCCTGACGCTCAACCGGCGCCTGCACCGCGCCTACAACCGGACCCGCGAGGGCGATTTCTCGCTGCATGGGCTGACCGGCTTCGACCTCCACGGCAAACGCGTCGGAGTGATCGGCACCGGACAGATCGGCGAGACCTTCGCCCGCATCATGGCCGGCTTCGGCTGCGAGCTGCTGGCCTACGATCCTTATCCCAATCCGCGCATCCAAGCACTCGGCGGCCGCTACCTGGCGCTCGACGCCCTGCTCGCCGAGTCCGACATCGTCAGCCTGCATTGCCCGCTGACCGCCGACACCCGCCACCTCATCGACGCGCAGCGCCTGGCGACGATGAAACCCGGCGCGATGCTGATCAATACCGGCCGTGGCGCCCTGGTGAACGCCGCGGCGCTGATCGAGGCGCTGAAGAGCGGACAACTGGGCTACCTCGGCCTCGATGTCTATGAAGAGGAAGCGGATATCTTTTTCGAGGATCGCTCCGACCAGCCCCTGCAGGATGACGTGCTGGCACGCCTGCTGAGCTTCCCCAACGTGGTGGTGACGGCCCACCAGGCCTTCCTTACCCGCGAGGCCCTGGCGGCGATCGCCGACACCACCCTGGACAACATCGCCGCCTGGCAGGACGGGACGCCGCGCAATCGGGTCCGGGCCTGA
Protein Properties
Protein Residues: 329
Protein Molecular Weight: 35.8 kDa
Protein Theoretical pI: 6.14
Hydropathicity (GRAVY score): 0.042
Charge at pH 7 (predicted): -6.72
Protein Sequence: 
>PA0927
MRILFFSSQAYDSESFQASNHRHGFELHFQQAHLQADTAVLAQGFEVVCAFVNDDLSRPVLERLAAGGTRLVALRSAGYNHVDLAAAEALGLPVVHVPAYSPHAVAEHAVGLILTLNRRLHRAYNRTREGDFSLHGLTGFDLHGKRVGVIGTGQIGETFARIMAGFGCELLAYDPYPNPRIQALGGRYLALDALLAESDIVSLHCPLTADTRHLIDAQRLATMKPGAMLINTGRGALVNAAALIEALKSGQLGYLGLDVYEEEADIFFEDRSDQPLQDDVLARLLSFPNVVVTAHQAFLTREALAAIADTTLDNIAAWQDGTPRNRVRA
References
External Links:
Resource Link
Genome ID: PA0927
Entrez Gene ID: 881895
NCBI Protein ID: 15596124
General Reference: PaperBLAST - Find papers about PA0927 and its homologs