Methylisocitrate lyase (PA0796)

Identification
Name: Methylisocitrate lyase
Synonyms:
  • 2-methylisocitrate lyase
Gene Name: prpB
Enzyme Class:
Biological Properties
General Function: Involved in catalytic activity
Specific Function: Catalyzes the formation of pyruvate and succinate from 2-methylisocitrate
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb ↔ Thumb+Thumb
Methylisocitric acid ↔ Pyruvic acid + Succinic acid
ReactionCard
SMPDB Reactions:
Thumb → Thumb+Thumb
Methylisocitric acid → Succinic acid + Pyruvic acid
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb ↔ Thumb+Thumb
Methylisocitric acid ↔ Pyruvic acid + Succinic acid
ReactionCard
Complex Reactions: Not Available
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000674Methylisocitric acidMetaboCard
PAMDB000102Pyruvic acidMetaboCard
PAMDB000107Succinic acidMetaboCard
GO Classification:
Function
carbon-carbon lyase activity
catalytic activity
lyase activity
methylisocitrate lyase activity
oxo-acid-lyase activity
Process
carboxylic acid metabolic process
cellular metabolic process
metabolic process
monocarboxylic acid metabolic process
organic acid metabolic process
oxoacid metabolic process
propionate catabolic process
propionate catabolic process, 2-methylcitrate cycle
propionate metabolic process
Gene Properties
Locus tag: PA0796
Strand: -
Entrez Gene ID: 882026
Accession: NP_249487.1
GI: 15595993
Sequence start: 874206
Sequence End: 875102
Sequence Length: 896
Gene Sequence: 
>PA0796
ATGAGCCAGACGTCCCTTACCCCCGGCCAGCGCTTCCGCGAAGCCGTGGCCACCGAACACCCGCTGCAGGTGGTCGGCACCATCAACGCCAACCACGCCCTGCTGGCCAAGCGCGCCGGCTTCAAGGCCATCTACCTGTCCGGCGGCGGCGTCGCCGCCGGTTCCCTGGGCCTGCCGGACCTGGGTATCAGCGGCCTCGACGACGTGCTCACCGACGTGCGCCGGATCACCGACGTCTGCGACCTGCCGCTGCTGGTGGACGTCGACACCGGCTTCGGCTCCTCGGCGTTCAACGTCGCCCGCACGGTGAAGTCGATGATCAAGTTCGGCGCCGCCGCGATGCATATCGAGGACCAGGTCGGCGCCAAGCGCTGCGGCCATCGGCCGAACAAGGAGATCGTCTCGCAGCAGGAGATGGTCGACCGCATCAAGGCCGCCGTCGATGCCCGCAGCGACGACTCCTTCGTGATCATGGCGCGCACCGACGCGCTGGCCGTGGAAGGCCTGCAGGCCGCCATCGACCGCGCCTGCGCCTGTGTCGAGGCCGGTGCCGACATGATCTTCCCGGAAGCCATGACCGAACTGGCCATGTACAAGGAATTCGCCGCCGCGGTGAAGGTGCCGGTGCTGGCCAACATCACCGAGTTCGGCGCCACCCCGCTGTTCACCACCGACGAACTGGCCTCCGCCGACGTGTCCCTGGTGCTCTACCCGCTGTCGGCCTTCCGCGCCATGAACAAGGCGGCGGAGAACGTCTACACCGCGATCCGTCGCGACGGCACCCAGAAGAATGTGATCGATACCATGCAGACCCGCATGGAGCTGTACGATCGCATCGATTACCACAGCTTCGAGCAGAAGCTCGACGCGCTCTTCGCGCAGAAGAAGAACGCCTGA
Protein Properties
Protein Residues: 298
Protein Molecular Weight: 32.1 kDa
Protein Theoretical pI: 5.2
Hydropathicity (GRAVY score): 0.032
Charge at pH 7 (predicted): -5.92
Protein Sequence: 
>PA0796
MSQTSLTPGQRFREAVATEHPLQVVGTINANHALLAKRAGFKAIYLSGGGVAAGSLGLPDLGISGLDDVLTDVRRITDVCDLPLLVDVDTGFGSSAFNVARTVKSMIKFGAAAMHIEDQVGAKRCGHRPNKEIVSQQEMVDRIKAAVDARSDDSFVIMARTDALAVEGLQAAIDRACACVEAGADMIFPEAMTELAMYKEFAAAVKVPVLANITEFGATPLFTTDELASADVSLVLYPLSAFRAMNKAAENVYTAIRRDGTQKNVIDTMQTRMELYDRIDYHSFEQKLDALFAQKKNA
References
External Links:
Resource Link
Genome ID: PA0796
Entrez Gene ID: 882026
NCBI Protein ID: 15595993
General Reference: PaperBLAST - Find papers about PA0796 and its homologs