Phosphoenolpyruvate synthase (PA1770)

Identification
Name: Phosphoenolpyruvate synthase
Synonyms:
  • PEP synthase
  • Pyruvate, water dikinase
Gene Name: ppsA
Enzyme Class:
Biological Properties
General Function: Involved in catalytic activity
Specific Function: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb+Thumb ↔ Thumb+2 Thumb+Thumb+Thumb
Adenosine triphosphate + Water + Pyruvic acid ↔ Adenosine monophosphate + 2 Hydrogen ion + Phosphoenolpyruvic acid + Phosphate
ReactionCard
Thumb+Thumb+Thumb ↔ Thumb+Thumb+Thumb
Adenosine triphosphate + Pyruvic acid + Water ↔ Adenosine monophosphate + Phosphoenolpyruvic acid + Phosphate
ReactionCard
SMPDB Reactions:
Thumb+Thumb+Thumb+2 Thumb → Thumb+Thumb+Thumb
Phosphoenolpyruvic acid + Adenosine monophosphate + Phosphate + 2 Hydrogen ion → Adenosine triphosphate + Water + Pyruvic acid
ReactionCard
Thumb+Thumb+Thumb → Thumb+Thumb+2 Thumb+Thumb
Water + Adenosine triphosphate + Pyruvic acid → Adenosine monophosphate + Phosphate + 2 Hydrogen ion + Phosphoenolpyruvic acid
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb+Thumb+Thumb ↔ Thumb+2 Thumb+Thumb+Thumb
Adenosine triphosphate + Water + Pyruvic acid ↔ Adenosine monophosphate + 2 Hydrogen ion + Phosphoenolpyruvic acid + Phosphate
ReactionCard
Thumb+Thumb+Thumb ↔ Thumb+Thumb+Thumb
Adenosine triphosphate + Pyruvic acid + Water ↔ Adenosine monophosphate + Phosphoenolpyruvic acid + Phosphate
ReactionCard
Complex Reactions:
Thumb+Thumb+Thumb → Thumb+Thumb+Thumb
Adenosine triphosphate + Pyruvic acid + Water → Adenosine monophosphate + Phosphoenolpyruvic acid + Inorganic phosphate
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000014Adenosine monophosphateMetaboCard
PAMDB000148Adenosine triphosphateMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB001776Inorganic phosphateMetaboCard
PAMDB000383PhosphateMetaboCard
PAMDB000111Phosphoenolpyruvic acidMetaboCard
PAMDB000102Pyruvic acidMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Function
adenyl nucleotide binding
adenyl ribonucleotide binding
ATP binding
binding
catalytic activity
kinase activity
nucleoside binding
purine nucleoside binding
pyruvate, water dikinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
Process
alcohol metabolic process
cellular metabolic process
gluconeogenesis
glucose metabolic process
hexose metabolic process
metabolic process
monosaccharide metabolic process
phosphate metabolic process
phosphorus metabolic process
phosphorylation
small molecule metabolic process
Gene Properties
Locus tag: PA1770
Strand: +
Entrez Gene ID: 878597
Accession: NP_250461.1
GI: 15596967
Sequence start: 1914037
Sequence End: 1916412
Sequence Length: 2375
Gene Sequence: 
>PA1770
TTGGTAGAGTACGTAGTTTCCCTCGATAAGCTCGGCGTCCATGATGTAGAGCATGTGGGGGGCAAGAACGCATCCCTCGGCGAGATGATCAGCAACCTGGCCGGTGCCGGCGTTTCCGTACCCGGCGGATTTGCCACAACCGCCCAGGCCTACCGTGACTTCCTCGAGCAGAGTGGCCTCAACGACCGTATCCACGCGGCCCTGGACGCCCTGGACGTCGACGACGTCAACGCCCTGGCCAAGACCGGCGCGCAGATCCGCCAGTGGGTGATGGAAGCCGAGTTCCCGGCCCGTCTCGACAGCGAGATCCGCCAGGCCTTCGCCGCCCTGGCCAACGGCAACGACAACCTCGCCGTGGCAGTGCGTTCCTCCGCTACCGCCGAAGACCTTCCGGACGCCTCGTTCGCCGGCCAGCAGGAAACCTTCCTCAATATCCGCGGCGTGGACAATGTGATCCGCGCAGCAAAAGAGGTCTTCGCCTCCCTGTTCAACGACCGCGCCATCGCCTACCGCGTGCACCAGGGCTTCGACCACAAGCTGGTCGCCTTGTCCGCCGGCGTGCAGCGCATGGTCCGCTCGGAAACCGGCACCGCCGGGGTGATGTTCACCCTGGACACCGAATCCGGCTTCCGCGACGTGGTCTTCATCACTGGTGCCTACGGCCTGGGCGAGACCGTGGTCCAGGGCGCGGTGAACCCCGACGAGTTCTACGTCCACAAGCCGACCCTGGAAGCCGGGCGTCCGGCCATCCTGCGCCGCAACCTGGGTAGCAAGGCGATCAAGATGATCTACGGCGACGAAGCCAAGGCCGGTCGCTCGGTCAAGGTAGTGGACGTCGATCGCGCCGATCGCGCCCGCTTCGCCCTGAGCGACGCCGAGGTCACCGAGCTGGCCAAGCAGGCCATGATCATCGAGAAGCACTATGGCCGCCCGATGGACATCGAATGGGCCAAGGACGGTGACGACGGCAAGCTGTACATCGTCCAGGCACGCCCGGAAACCGTGAAGAGCCGCGCCAGCGCCACGGTCATGGAGCGCTACCTGCTGAAAGAGAAGGGGACCGTCCTGGTGGAAGGACGTGCCATCGGCCAGCGCATCGGTGCCGGTCCGGTCAAGGTGATCAACGACGTGTCGGAAATGGACAAGGTCCAACCGGGTGACGTCCTGGTCTCCGACATGACCGACCCGGACTGGGAGCCGGTGATGAAGCGCGCCAGCGCCATCGTCACCAACCGCGGCGGGCGCACCTGCCACGCGGCGATCATCGCTCGCGAACTGGGCATCCCGGCGGTGGTCGGTTGCGGCAATGCCACCCAGATCCTGCAGGATGGCCAGGGGGTGACCGTTTCCTGTGCCGAAGGCGATACCGGCTTCATCTTCGAAGGCGAACTCGGTTTCGATGTGCGCAAGAACTCGGTCGACGCCATGCCCGACCTTCCGTTCAAGATCATGATGAACGTCGGCAATCCCGATCGCGCTTTCGATTTCGCCCAGTTGCCGAACGAAGGCGTGGGCCTGGCCCGCCTCGAATTCATCATCAACCGCATGATCGGCGTGCACCCCAAGGCGTTGCTGAACTTCGCCGGCCTGCCGGCGGACATCAAGGAAAGCGTGGAGAAGCGCATCGCCGGCTATCCCGATCCGGTCGGCTTCTACGTCGAGAAGCTGGTGGAGGGCATCAGCACCCTGGCCGCGGCGTTCTGGCCGAAGAAGGTCATCGTGCGCCTGTCCGACTTCAAGTCCAATGAGTACGCCAACCTGATCGGCGGCAAGCTCTACGAGCCGGAAGAAGAGAACCCGATGCTCGGCTTCCGTGGCGCCTCGCGCTACATCAGCGAGTCGTTCCGCGACTGCTTCGAGCTGGAGTGTCGTGCGCTGAAGAAGGTCCGCAACGAAATGGGCCTGACCAACGTCGAGATCATGGTGCCCTTCGTGCGCACCCTGGGCGAGGCGAGCCAGGTGGTCGAGCTGCTGGCCGGGAACGGCCTGAAGCGCGGCGAGAACGGACTGAAGGTCATCATGATGTGCGAACTGCCGTCGAACGCCCTGCTGGCCGACGAGTTCCTCGAGTTCTTCGATGGCTTCTCCATCGGTTCCAACGACCTGACCCAGCTGACCCTGGGCCTGGATCGCGATTCCGGCATCGTTGCCCACCTGTTCGACGAGCGCAATCCGGCGGTGAAGAAGCTGCTGGCCAACGCCATCGCTGCCTGCAACAAGGCCGGCAAGTACATCGGCATCTGCGGCCAGGGTCCGTCGGACCACCCGGACCTGGCCCGCTGGCTGATGGAGCAGGGCATCGAGAGCGTCTCGTTGAACCCCGACTCGGTGCTGGATACCTGGTTCTTCCTCGCCGAGGGGCAAGACCAGGCCTGA
Protein Properties
Protein Residues: 791
Protein Molecular Weight: 85.8 kDa
Protein Theoretical pI: 4.78
Hydropathicity (GRAVY score): -0.082
Charge at pH 7 (predicted): -24.53
Protein Sequence: 
>PA1770
MVEYVVSLDKLGVHDVEHVGGKNASLGEMISNLAGAGVSVPGGFATTAQAYRDFLEQSGLNDRIHAALDALDVDDVNALAKTGAQIRQWVMEAEFPARLDSEIRQAFAALANGNDNLAVAVRSSATAEDLPDASFAGQQETFLNIRGVDNVIRAAKEVFASLFNDRAIAYRVHQGFDHKLVALSAGVQRMVRSETGTAGVMFTLDTESGFRDVVFITGAYGLGETVVQGAVNPDEFYVHKPTLEAGRPAILRRNLGSKAIKMIYGDEAKAGRSVKVVDVDRADRARFALSDAEVTELAKQAMIIEKHYGRPMDIEWAKDGDDGKLYIVQARPETVKSRASATVMERYLLKEKGTVLVEGRAIGQRIGAGPVKVINDVSEMDKVQPGDVLVSDMTDPDWEPVMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCGNATQILQDGQGVTVSCAEGDTGFIFEGELGFDVRKNSVDAMPDLPFKIMMNVGNPDRAFDFAQLPNEGVGLARLEFIINRMIGVHPKALLNFAGLPADIKESVEKRIAGYPDPVGFYVEKLVEGISTLAAAFWPKKVIVRLSDFKSNEYANLIGGKLYEPEEENPMLGFRGASRYISESFRDCFELECRALKKVRNEMGLTNVEIMVPFVRTLGEASQVVELLAGNGLKRGENGLKVIMMCELPSNALLADEFLEFFDGFSIGSNDLTQLTLGLDRDSGIVAHLFDERNPAVKKLLANAIAACNKAGKYIGICGQGPSDHPDLARWLMEQGIESVSLNPDSVLDTWFFLAEGQDQA
References
External Links:
Resource Link
Genome ID: PA1770
Entrez Gene ID: 878597
NCBI Protein ID: 15596967
General Reference: PaperBLAST - Find papers about PA1770 and its homologs