Anthranilate synthase component 1 (PA0609)

Identification
Name: Anthranilate synthase component 1
Synonyms:
  • Anthranilate synthase component I
Gene Name: trpE
Enzyme Class:
Biological Properties
General Function: Involved in biosynthetic process
Specific Function: Chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb ↔ Thumb+Thumb+Thumb+Thumb
Chorismate + L-Glutamine ↔ 2-Aminobenzoic acid + L-Glutamate + Hydrogen ion + Pyruvic acid
ReactionCard
Thumb+Thumb ↔ Thumb+Thumb+Thumb
Chorismate + Ammonia ↔ 2-Aminobenzoic acid + Pyruvic acid + Water
ReactionCard
Thumb+Thumb ↔ Thumb+Thumb+Thumb
Chorismate + L-Glutamine ↔ 2-Aminobenzoic acid + Pyruvic acid + L-Glutamate
ReactionCard
Thumb+Thumb → Thumb+Thumb+Thumb+Thumb
Chorismate + L-Glutamine → Hydrogen ion + 2-Aminobenzoic acid + Pyruvic acid + L-Glutamate
ReactionCard
SMPDB Reactions:
Thumb+Thumb → L-Glutamic acid+Thumb+Thumb+Thumb+Thumb
Chorismate + L-Glutamine → L-Glutamic acid + Pyruvic acid + Hydrogen ion + 2-Aminobenzoic acid + L-Glutamate
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb+Thumb ↔ Thumb+Thumb+Thumb+Thumb
Chorismate + L-Glutamine ↔ 2-Aminobenzoic acid + L-Glutamate + Hydrogen ion + Pyruvic acid
ReactionCard
Thumb+Thumb → Thumb+Thumb+Thumb+Thumb
Chorismate + L-Glutamine → Hydrogen ion + 2-Aminobenzoic acid + Pyruvic acid + L-Glutamate
ReactionCard
Complex Reactions:
Thumb+Thumb → Thumb+Thumb+Thumb
Chorismate + L-Glutamine → 2-Aminobenzoic acid + Pyruvic acid + L-Glutamate
ReactionCard
Thumb+Thumb → Thumb+Thumb+Thumb
Chorismate + L-Glutamine → 2-Aminobenzoic acid + Pyruvic acid + L-Glutamate
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB0002622-Aminobenzoic acidMetaboCard
PAMDB000017AmmoniaMetaboCard
PAMDB000828ChorismateMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000055L-GlutamateMetaboCard
PAMDB000163L-GlutamineMetaboCard
PAMDB000102Pyruvic acidMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Function
anthranilate synthase activity
carbon-carbon lyase activity
catalytic activity
lyase activity
oxo-acid-lyase activity
Process
biosynthetic process
metabolic process
Gene Properties
Locus tag: PA0609
Strand: +
Entrez Gene ID: 879191
Accession: NP_249300.1
GI: 15595806
Sequence start: 670980
Sequence End: 672458
Sequence Length: 1478
Gene Sequence: 
>PA0609
ATGAATCGCGAAGAATTCCTGCGGCTGGCCGCCGATGGCTACAACCGCATCCCGCTGTCCTTCGAGACCCTTGCCGACTTCGACACGCCGCTGTCGATCTACCTGAAGCTGGCCGACGCGCCGAACTCCTACCTGCTGGAGTCGGTGCAGGGCGGCGAGAAATGGGGGCGCTATTCGATCATCGGCCTGCCGTGCCGCACGGTGCTGCGGGTCTACGACCATCAAGTGCGGATCAGCATCGATGGCGTGGAAACCGAGCGCTTCGATTGCGCCGACCCGTTGGCTTTCGTCGAGGAGTTCAAGGCGCGCTACCAGGTGCCCACCGTGCCCGGCTTGCCACGTTTCGATGGCGGCCTGGTCGGCTACTTCGGTTACGACTGCGTGCGCTACGTGGAAAAACGCCTGGCCACCTGTCCGAACCCGGACCCGCTGGGCAACCCGGATATCCTGTTGATGGTGTCCGATGCCGTAGTGGTATTCGACAACCTGGCCGGGAAGATCCACGCCATCGTCCTCGCCGATCCCTCCGAGGAAAATGCCTACGAGCGCGGCCAGGCACGTCTGGAGGAGCTGCTGGAGCGTCTACGCCAGCCGATCACCCCGCGTCGCGGCCTCGACCTCGAGGCGGCCCAGGGTCGTGAGCCGGCGTTTCGTGCCAGCTTCACCCGCGAGGACTATGAAAACGCGGTAGGAAGGATCAAGGACTACATCCTGGCCGGCGACTGCATGCAGGTGGTGCCGTCGCAGCGCATGTCCATCGAATTCAAGGCGGCGCCCATCGACCTGTACCGCGCGCTGCGCTGTTTCAATCCGACGCCCTACATGTACTTCTTCAACTTCGGCGACTTCCATGTCGTGGGCAGCTCGCCGGAGGTGCTGGTACGGGTCGAGGATGGCCTGGTGACGGTGCGCCCGATCGCCGGTACCCGTCCGCGCGGGATCAACGAAGAGGCCGACCTGGCACTGGAGCAGGATCTGCTGTCGGACGCCAAGGAGATCGCCGAGCACCTGATGCTGATCGACCTGGGGCGCAACGACGTGGGGCGGGTGTCCGATATCGGCGCGGTGAAGGTCACCGAAAAAATGGTGATCGAACGTTACTCCAACGTCATGCACATCGTGTCCAACGTCACCGGGCAATTGCGCGAGGGGCTCAGCGCGATGGACGCGCTGCGGGCGATTCTGCCGGCGGGCACTCTATCCGGCGCGCCGAAGATCCGCGCCATGGAGATCATCGACGAGCTGGAGCCGGTCAAGCGTGGAGTCTACGGCGGCGCGGTCGGCTACCTGGCATGGAACGGCAACATGGACACCGCCATTGCCATCCGCACCGCGGTGATCAAGAACGGTGAACTCCACGTGCAGGCCGGCGGCGGTATCGTTGCCGACTCGGTGCCCGCGCTGGAGTGGGAAGAAACCATCAACAAGCGCCGGGCGATGTTCCGCGCCGTGGCGCTGGCCGAGCAGAGCGTCGAATAA
Protein Properties
Protein Residues: 492
Protein Molecular Weight: 54.6 kDa
Protein Theoretical pI: 4.72
Hydropathicity (GRAVY score): -0.105
Charge at pH 7 (predicted): -16.71
Protein Sequence: 
>PA0609
MNREEFLRLAADGYNRIPLSFETLADFDTPLSIYLKLADAPNSYLLESVQGGEKWGRYSIIGLPCRTVLRVYDHQVRISIDGVETERFDCADPLAFVEEFKARYQVPTVPGLPRFDGGLVGYFGYDCVRYVEKRLATCPNPDPLGNPDILLMVSDAVVVFDNLAGKIHAIVLADPSEENAYERGQARLEELLERLRQPITPRRGLDLEAAQGREPAFRASFTREDYENAVGRIKDYILAGDCMQVVPSQRMSIEFKAAPIDLYRALRCFNPTPYMYFFNFGDFHVVGSSPEVLVRVEDGLVTVRPIAGTRPRGINEEADLALEQDLLSDAKEIAEHLMLIDLGRNDVGRVSDIGAVKVTEKMVIERYSNVMHIVSNVTGQLREGLSAMDALRAILPAGTLSGAPKIRAMEIIDELEPVKRGVYGGAVGYLAWNGNMDTAIAIRTAVIKNGELHVQAGGGIVADSVPALEWEETINKRRAMFRAVALAEQSVE
References
External Links:
Resource Link
Genome ID: PA0609
Entrez Gene ID: 879191
NCBI Protein ID: 15595806
General Reference: PaperBLAST - Find papers about PA0609 and its homologs