Alkanesulfonate monooxygenase (PA3444)

Identification
Name: Alkanesulfonate monooxygenase
Synonyms:
  • FMNH2-dependent aliphatic sulfonate monooxygenase
  • Sulfate starvation-induced protein 6
  • SSI6
Gene Name: ssuD
Enzyme Class:
Biological Properties
General Function: oxidation-reduction process
Specific Function: alkanesulfonate monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb+Thumb ↔ Thumb+Thumb+Thumb+Thumb
Alkanesulfonate + FMNH + Oxygen ↔ Aldehyde + Flavin Mononucleotide + Sulfite + Water
ReactionCard
SMPDB Reactions:
alkylsulfonate+Thumb+Thumb → Thumb+Sulfite+Thumb+Thumb+2 Thumb+Thumb
alkylsulfonate + FMNH2 + Oxygen → Betaine aldehyde + Sulfite + Flavin Mononucleotide + Water + 2 Hydrogen ion + Sulfite
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Thumb+Thumb+Thumb → Thumb+Thumb+Sulfite+Thumb+Thumb+Thumb
Butanesulfonate + Oxygen + FMNH2 → Hydrogen ion + Water + Sulfite + Flavin Mononucleotide + Betaine aldehyde + Sulfite
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Thumb+Thumb+Thumb → Sulfite+Thumb+Thumb+Thumb+Thumb+Thumb
Oxygen + FMNH2 + 3-(N-morpholino)propanesulfonate → Sulfite + Water + Hydrogen ion + Flavin Mononucleotide + Betaine aldehyde + Sulfite
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Thumb+Thumb+Thumb → Thumb+Thumb+Thumb+Sulfite+Thumb+Thumb
ethanesulfonate + Oxygen + FMNH2 → Hydrogen ion + Water + Flavin Mononucleotide + Sulfite + Betaine aldehyde + Sulfite
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Thumb+Thumb+Thumb → Thumb+Thumb+Thumb+Thumb+Sulfite+Thumb
isethionate + Oxygen + FMNH2 → Betaine aldehyde + Flavin Mononucleotide + Hydrogen ion + Water + Sulfite + Sulfite
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Thumb+methanesulfonate+Thumb+Thumb → Thumb+Thumb+Thumb+Sulfite+Thumb+Thumb
Oxygen + methanesulfonate + FMNH2 + Methanesulfonate → Hydrogen ion + Water + Flavin Mononucleotide + Sulfite + Betaine aldehyde + Sulfite
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb+Thumb+Thumb → Thumb+Thumb+Thumb+Thumb+Thumb
FMNH + Isethionic acid + Oxygen → Flavin Mononucleotide + Glycolaldehyde + Hydrogen ion + Water + Sulfite
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Thumb+Thumb+Thumb → Thumb+Thumb+Thumb+Thumb+Thumb
Butanesulfonate + FMNH + Oxygen → Butanal + Flavin Mononucleotide + Hydrogen ion + Water + Sulfite
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Complex Reactions:
Thumb+Thumb+Thumb → Thumb+Thumb+Thumb+Thumb+Thumb
FMNH + Oxygen + Sulfoacetate → Flavin Mononucleotide + Glyoxylic acid + Hydrogen ion + Water + Sulfite
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Thumb+Thumb+Thumb → Thumb+Thumb+Thumb+Thumb+Thumb
FMNH + Methanesulfonate + Oxygen → Formaldehyde + Flavin Mononucleotide + Hydrogen ion + Water + Sulfite
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Thumb+Thumb+Thumb → Thumb+Thumb+Thumb+Thumb+Thumb
Ethanesulfonate + FMNH + Oxygen → Acetaldehyde + Flavin Mononucleotide + Hydrogen ion + Water + Sulfite
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An alkanesufonate (R-CH(2)-SO(3)H)+Thumb+Thumb → an aldehyde (R-CHO)+Thumb+Thumb+Thumb
An alkanesufonate (R-CH(2)-SO(3)H) + FMNH(2) + Oxygen → an aldehyde (R-CHO) + Flavin Mononucleotide + Sulfite + Water
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB006371 ethanesulfonateMetaboCard
PAMDB006372 isethionateMetaboCard
PAMDB0063703-(N-morpholino)propanesulfonateMetaboCard
PAMDB000217AcetaldehydeMetaboCard
PAMDB002040AldehydeMetaboCard
PAMDB004197AlkanesulfonateMetaboCard
PAMDB000309Betaine aldehydeMetaboCard
PAMDB000512ButanalMetaboCard
PAMDB001715ButanesulfonateMetaboCard
PAMDB001731EthanesulfonateMetaboCard
PAMDB000408Flavin MononucleotideMetaboCard
PAMDB000273FMNHMetaboCard
PAMDB003577FMNH(2)MetaboCard
PAMDB006176FMNH2MetaboCard
PAMDB000382FormaldehydeMetaboCard
PAMDB000444GlycolaldehydeMetaboCard
PAMDB000043Glyoxylic acidMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB001641Isethionic acidMetaboCard
PAMDB001743MethanesulfonateMetaboCard
PAMDB000624OxygenMetaboCard
PAMDB000100SulfiteMetaboCard
PAMDB001755SulfoacetateMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Function
alkanesulfonate monooxygenase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
Process
oxidation-reduction process
Gene Properties
Locus tag: PA3444
Strand: -
Entrez Gene ID: 879163
Accession: NP_252134.1
GI: 15598640
Sequence start: 3849604
Sequence End: 3850752
Sequence Length: 1148
Gene Sequence: 
>PA3444
ATGAGCCTCGAGATTTTCTGGTTCCTTCCCACCCACGGCGACGGCCACTACCTGGGCACCACCCAGGGCGCCCGTGCCGTCGACCACGGCTACCTGCAGCAGATCGCCCAGGCCGCCGACCGTCTGGGCTTCGGCGGCGTACTGATCCCCACCGGACGTTCCTGCGAGGACTCCTGGCTGGTCGCCGCCTCGCTGATCCCGGTAACCCAGCGCCTGAAGTTCCTCGTCGCGCTGCGTCCCGGGATCATTTCGCCGACCGTCGCCGCGCGCCAGGCGGCGACCCTGGACCGGCTGTCCAACGGCCGCGCGCTGTTCAACCTGGTCACCGGCGGCGATCCCGACGAACTGGCTGGCGACGGCCTGCACCTGAGCCACGCCGAACGCTACGAGGCGTCGGTCGAATTCACCCGCATCTGGCGTCGCGTGCTGGAGGGCGAGACCGTCGACTACGCCGGCAAGCACATCCAGGTGAAGGGCGCCAAACTGCTCTATCCGCCGTTGCAGCAGCCGCGTCCGCCGCTGTACTTCGGCGGCTCCTCGGAGGCCGCCCAGGACCTCGCCGCCGAGCAGGTCGAGCTGTACCTGACCTGGGGCGAGCCGCCGGCGGCGGTTGCCGAGAAGATCGCCCAGGTACGCGAGAAGGCTGCCCGCCAGGGCCGCCAGGTGCGCTTCGGGATCCGCCTGCACGTGATCGTCCGCGAGACCAGCGAGGAAGCCTGGCAGGCCGCCGATCGCCTGATCGCGCACCTCGACGACGACACCATCGCCCGCGCCCAGGCCTCCCTGGCGCGCTTCGACTCGGTCGGCCAGCAACGCATGGCCGCGCTGCACGGCGGTTCGCGCGACAACCTGGAAGTCAGCCCCAATCTCTGGGCCGGCGTCGGCCTGGTGCGCGGCGGCGCCGGCACCGCGCTGGTCGGCGACGGGCCGACGGTGGCGGCGCGGGTCAGGGAGTACGCCGAGCTGGGCATCGATACCTTCATCTTCTCCGGCTATCCGCACCTGGAAGAGTCCTACCGGGTCGCCGAACTGCTGTTCCCGCACCTCGACGTGCAGCGCCCGGCGCAGCCCGAGGGACGCGGCTATGTCAGCCCGTTCGGCGAGATGGTGGCCAACGACATCCTGCCCCGGCAGGCCGCGCAGAGTTGA
Protein Properties
Protein Residues: 382
Protein Molecular Weight: 41.6 kDa
Protein Theoretical pI: 6.14
Hydropathicity (GRAVY score): -0.175
Charge at pH 7 (predicted): -5.37
Protein Sequence: 
>PA3444
MSLEIFWFLPTHGDGHYLGTTQGARAVDHGYLQQIAQAADRLGFGGVLIPTGRSCEDSWLVAASLIPVTQRLKFLVALRPGIISPTVAARQAATLDRLSNGRALFNLVTGGDPDELAGDGLHLSHAERYEASVEFTRIWRRVLEGETVDYAGKHIQVKGAKLLYPPLQQPRPPLYFGGSSEAAQDLAAEQVELYLTWGEPPAAVAEKIAQVREKAARQGRQVRFGIRLHVIVRETSEEAWQAADRLIAHLDDDTIARAQASLARFDSVGQQRMAALHGGSRDNLEVSPNLWAGVGLVRGGAGTALVGDGPTVAARVREYAELGIDTFIFSGYPHLEESYRVAELLFPHLDVQRPAQPEGRGYVSPFGEMVANDILPRQAAQS
References
External Links:
Resource Link
Genome ID: PA3444
Entrez Gene ID: 879163
NCBI Protein ID: 15598640
General Reference: PaperBLAST - Find papers about PA3444 and its homologs