Identification
Name: Adenylate kinase
Synonyms:
  • AK
  • ATP-AMP transphosphorylase
Gene Name: adk
Enzyme Class:
Biological Properties
General Function: Involved in ATP binding
Specific Function: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. This small ubiquitous enzyme involved in the energy metabolism and nucleotide synthesis, is essential for maintenance and cell growth
Cellular Location: Cytoplasm
KEGG Pathways:
KEGG Reactions:
Thumb+ThumbThumb+Thumb
Thumb+ThumbThumb+Thumb
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Thumb+ThumbThumb+Thumb
Thumb+ThumbThumb+Thumb
Thumb+ThumbThumb+Thumb
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Thumb+ThumbThumb+Thumb
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Thumb+Thumb2 Thumb
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SMPDB Reactions:
ThumbThumb+Adenosine diphosphate+Thumb
PseudoCyc/BioCyc Reactions:
Thumb+ThumbThumb+Thumb
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Thumb+ThumbThumb+Thumb
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Thumb+Thumb2 Thumb
Complex Reactions:
Thumb+ThumbThumb+Thumb
Thumb+ThumbThumb+Thumb
Thumb+ThumbThumb+Thumb+Thumb
Thumb+Thumb2 Thumb
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000016AdenosineMetaboCard
PAMDB000014Adenosine monophosphateMetaboCard
PAMDB000148Adenosine triphosphateMetaboCard
PAMDB000345ADPMetaboCard
PAMDB000415CDPMetaboCard
PAMDB000030Cytidine triphosphateMetaboCard
PAMDB001728dADPMetaboCard
PAMDB000412dATPMetaboCard
PAMDB000307dCDPMetaboCard
PAMDB000219dCTPMetaboCard
PAMDB000199Deoxyadenosine monophosphateMetaboCard
PAMDB000290Deoxyuridine triphosphateMetaboCard
PAMDB000209dGDPMetaboCard
PAMDB000389dGTPMetaboCard
PAMDB000320dTDPMetaboCard
PAMDB000221dUDPMetaboCard
PAMDB000296Guanosine diphosphateMetaboCard
PAMDB000319Guanosine triphosphateMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000490IDPMetaboCard
PAMDB000078Inosine triphosphateMetaboCard
PAMDB000346Thymidine 5'-triphosphateMetaboCard
PAMDB000123Uridine 5'-diphosphateMetaboCard
PAMDB000117Uridine triphosphateMetaboCard
GO Classification:
Function
adenyl nucleotide binding
adenyl ribonucleotide binding
adenylate kinase activity
ATP binding
binding
catalytic activity
kinase activity
nucleobase, nucleoside, nucleotide kinase activity
nucleoside binding
nucleotide kinase activity
phosphotransferase activity, phosphate group as acceptor
purine nucleoside binding
transferase activity
transferase activity, transferring phosphorus-containing groups
Process
cellular nitrogen compound metabolic process
metabolic process
nitrogen compound metabolic process
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
Gene Properties
Locus tag: PA3686
Strand: -
Entrez Gene ID: 879082
Accession: NP_252376.1
GI: 15598882
Sequence start: 4126948
Sequence End: 4127595
Sequence Length: 647
Gene Sequence:
>PA3686
ATGCGTGTGATTCTGCTCGGGGCACCCGGTGCCGGCAAAGGCACCCAGGCACGGTTCATCACCGAGAAGTTCGGCATTCCGCAGATCTCCACCGGCGACATGCTGCGCGCCGCAGTCAAGGCCGGCAGCCCGCTCGGCCAGCAGGTGAAAGGCGTGATGGACAGCGGCGGCCTGGTATCCGACGACATCATCATCGCCCTGATCAAGGAACGCATCACCGAGGCCGATTGCGCCAAGGGCTTCCTGTTCGACGGCTTCCCGCGGACCATCCCGCAGGCCGAAGCGCTGAAGGACGCCGGCGTGACCATCGACCATGTGGTCGAGATCGCCGTCGACGACGAGGAGATCGTGTCGCGTATCGCCGGTCGTCGCGTGCATCCGGCCTCCGGCCGCGTGTACCACACCGAGCACAACCCGCCGAAGGTCGCCGGCAAGGACGACGTTACCGGCGAAGAGCTGATCCAGCGCGAGGACGACAAGGAAGAGACCGTGCGTCACCGCCTGTCGGTCTACCATTCGCAGACCAAGCCGCTGGTCGACTTCTACCAGAAGCTGTCGGCCGCCGAAGGCACCCCGAAATACCACAGCATCGCCGGCGTCGGCTCGGTCGAGCAGATCACCGCGAAAGTGCTTTCGGCCCTGAGCTGA
Protein Properties
Protein Residues: 215
Protein Molecular Weight: 23.1 kDa
Protein Theoretical pI: 6.4
Hydropathicity (GRAVY score): -0.2
Charge at pH 7 (predicted): -2.35
Protein Sequence:
>PA3686
MRVILLGAPGAGKGTQARFITEKFGIPQISTGDMLRAAVKAGSPLGQQVKGVMDSGGLVSDDIIIALIKERITEADCAKGFLFDGFPRTIPQAEALKDAGVTIDHVVEIAVDDEEIVSRIAGRRVHPASGRVYHTEHNPPKVAGKDDVTGEELIQREDDKEETVRHRLSVYHSQTKPLVDFYQKLSAAEGTPKYHSIAGVGSVEQITAKVLSALS
References
External Links:
Resource Link
Genome ID: PA3686
Entrez Gene ID: 879082
NCBI Protein ID: 15598882
General Reference: PaperBLAST - Find papers about PA3686 and its homologs