Identification
Name: Sulfate/thiosulfate import ATP-binding protein cysA
Synonyms:
  • Sulfate-transporting ATPase
Gene Name: cysA
Enzyme Class:
Biological Properties
General Function: Involved in nucleotide binding
Specific Function: Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system
Cellular Location: Cell inner membrane; Peripheral membrane protein
KEGG Pathways:
KEGG Reactions: Not Available
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb+Thumb+sulfate(Out)Thumb+Thumb+sulfate(In)
Thumb+Thumb+Sulfate+ThumbAdenosine diphosphate+Thumb+Thumb+Sulfate+Thumb
Adenosine triphosphate + Water + Sulfate + Sulfate → Adenosine diphosphate + Phosphate + Hydrogen ion + Sulfate + ADP
ReactionCard
Complex Reactions: Not Available
Transports:
Metabolites:
PAMDB IDNameView
PAMDB000148Adenosine triphosphateMetaboCard
PAMDB000345ADPMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB001776Inorganic phosphateMetaboCard
PAMDB001654MolybdateMetaboCard
PAMDB000383PhosphateMetaboCard
PAMDB001752SeleniteMetaboCard
PAMDB000666SelenocystathionineMetaboCard
PAMDB000391SulfateMetaboCard
PAMDB000108ThiosulfateMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Component
ATP-binding cassette (ABC) transporter complex
cell part
macromolecular complex
membrane
protein complex
Function
active transmembrane transporter activity
adenyl nucleotide binding
adenyl ribonucleotide binding
anion transmembrane transporter activity
ATP binding
ATPase activity
ATPase activity, coupled to transmembrane movement of substances
binding
catalytic activity
hydrolase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
inorganic anion transmembrane transporter activity
ion transmembrane transporter activity
nucleoside binding
nucleoside-triphosphatase activity
nucleotide binding
P-P-bond-hydrolysis-driven transmembrane transporter activity
primary active transmembrane transporter activity
purine nucleoside binding
pyrophosphatase activity
substrate-specific transmembrane transporter activity
sulfate transmembrane transporter activity
sulfate transmembrane-transporting ATPase activity
transmembrane transporter activity
transporter activity
Process
anion transport
establishment of localization
inorganic anion transport
ion transport
sulfate transport
transport
Gene Properties
Locus tag: PA0280
Strand: -
Entrez Gene ID: 877644
Accession: NP_248971.1
GI: 15595477
Sequence start: 313938
Sequence End: 314927
Sequence Length: 989
Gene Sequence:
>PA0280
ATGAGCATCGAAATCCGTAACGTCAGCAAGAACTTCAACGCCTTCAAGGCCCTGGACGACATCAACCTGGACATCCAGAGCGGCGAGCTGGTGGCCCTGCTCGGCCCCTCCGGGTGCGGCAAGACCACCCTGCTGCGGATCATCGCCGGGCTGGAAACCCCGGACGCCGGCAACATCGTGTTCCATGGCGAGGACGTCTCGCAGCACGACGTGCGCGACCGCAACGTCGGCTTCGTCTTCCAGCACTACGCGCTGTTCCGCCACATGACGGTGTTCGACAACGTCGCCTTCGGCCTGCGCATGAAGCCCAAGGGCGAGCGGCCGGGCGAGTCCGCGATCAAGGCCAAGGTCCACGAGCTGCTCAACATGGTGCAGCTCGACTGGCTCGCCGACCGCTATCCCGAGCAGCTCTCCGGTGGCCAGCGGCAGCGTATCGCCCTGGCCCGCGCGCTGGCGGTGGAGCCGAAGATCCTGCTCCTCGACGAACCCTTCGGCGCCCTCGACGCCAAGGTACGCAAGGAGCTGCGCCGCTGGCTGGCGCGCCTGCACGAGGAGATCAACCTGACCTCGGTGTTCGTCACCCACGACCAGGAAGAAGCGATGGAAGTGGCCGACCGCATCGTGGTGATGAACAAGGGCGTGATCGAGCAGATCGGCTCGCCCGGCGAGGTCTACGAGAACCCGGCCAGCGATTTCGTCTACCACTTCCTCGGCGACTCCAACCGCCTGCAACTGGGCAACGACCAGCACCTGCTGTTCCGCCCCCACGAAGTGTCGCTGTCGCGTTCCGCGGTGGCCGAGCACCGCGCCGCCGAGGTCCGCGACATCCGTCCGCTGGGGGCGATCACCCGGGTAACGCTGAAGGTCGACGGCCAGGACGAACTGATCGAAGCCGAAGTGGTGAAGGACCACGACAGCCTGGCCGGCCTGGCCCGCGGCGAGACCCTCTACTTCAAGCCGAAGGCCTTCCAGCCGGTGGCCAATCTCTGA
Protein Properties
Protein Residues: 329
Protein Molecular Weight: 36.8 kDa
Protein Theoretical pI: 6.1
Hydropathicity (GRAVY score): -0.217
Charge at pH 7 (predicted): -6.13
Protein Sequence:
>PA0280
MSIEIRNVSKNFNAFKALDDINLDIQSGELVALLGPSGCGKTTLLRIIAGLETPDAGNIVFHGEDVSQHDVRDRNVGFVFQHYALFRHMTVFDNVAFGLRMKPKGERPGESAIKAKVHELLNMVQLDWLADRYPEQLSGGQRQRIALARALAVEPKILLLDEPFGALDAKVRKELRRWLARLHEEINLTSVFVTHDQEEAMEVADRIVVMNKGVIEQIGSPGEVYENPASDFVYHFLGDSNRLQLGNDQHLLFRPHEVSLSRSAVAEHRAAEVRDIRPLGAITRVTLKVDGQDELIEAEVVKDHDSLAGLARGETLYFKPKAFQPVANL
References
External Links:
Resource Link
Genome ID: PA0280
Entrez Gene ID: 877644
NCBI Protein ID: 15595477
General Reference: PaperBLAST - Find papers about PA0280 and its homologs