NADP-dependent L-serine/L-allo-threonine dehydrogenase ydfG (PA4907)

Identification
Name: NADP-dependent L-serine/L-allo-threonine dehydrogenase ydfG
Synonyms: Not Available
Gene Name: ydfG
Enzyme Class:
Biological Properties
General Function: Involved in oxidoreductase activity
Specific Function: Catalyzes the NADP-dependent oxidation of L-allo- threonine to L-2-amino-3-keto-butyrate, which is spontaneously decarboxylated into aminoacetone. Also acts on L-serine, D-serine, D-threonine, D-3-hydroxyisobutyrate, L-3-hydroxyisobutyrate, D- glycerate and L-glycerate
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb+Thumb → Thumb+Thumb
Hydrogen ion + Malonic semialdehyde + NADPH → 3-Hydroxypropanoate + NADP
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Thumb+Thumb ↔ Thumb+Thumb+Thumb
3-Hydroxypropanoate + NADP ↔ Malonic semialdehyde + NADPH + Hydrogen ion
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Thumb+Thumb+Thumb ↔ Thumb+Thumb+Thumb+Thumb
L-Allothreonine + NADP + L-2-Amino-3-oxobutanoic acid ↔ Aminoacetone + Carbon dioxide + NADPH + Hydrogen ion
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SMPDB Reactions:
Thumb+Thumb+Thumb ↔ Thumb+Thumb
2-Aminomalonate semialdehyde + NADPH + Hydrogen ion ↔ NADP + L-Serine
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Thumb+Thumb+Thumb → Thumb+Thumb
Malonic semialdehyde + NADPH + Hydrogen ion → 3-Hydroxypropanoate + NADP
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PseudoCyc/BioCyc Reactions:
Thumb+Thumb+Thumb → Thumb+Thumb
Hydrogen ion + Malonic semialdehyde + NADPH → 3-Hydroxypropanoate + NADP
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Thumb+Thumb ↔ Thumb+Thumb+Thumb
NADP + L-Serine ↔ 2-Aminomalonate semialdehyde + Hydrogen ion + NADPH
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Complex Reactions:
Thumb+Thumb ↔ Thumb+Thumb+Thumb
NADP + D-Serine ↔ 2-Aminomalonate semialdehyde + Hydrogen ion + NADPH
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Thumb+Thumb ↔ Thumb+Thumb+Thumb
L-Allothreonine + NADP ↔ L-2-Amino-3-oxobutanoic acid + Hydrogen ion + NADPH
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Thumb+Thumb → Thumb+Thumb
3-Hydroxypropanoate + NADP → Malonic semialdehyde + NADPH
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Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB0015622-Aminomalonate semialdehydeMetaboCard
PAMDB0000053-Hydroxyisobutyric acidMetaboCard
3-HydroxypropanoateMetaboCard
PAMDB000441AminoacetoneMetaboCard
PAMDB000568Carbon dioxideMetaboCard
PAMDB000497D-SerineMetaboCard
PAMDB001914D-ThreonineMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000671L-2-Amino-3-oxobutanoic acidMetaboCard
PAMDB001426L-AllothreonineMetaboCard
PAMDB000077L-SerineMetaboCard
PAMDB000474Malonic semialdehydeMetaboCard
PAMDB000089NADPMetaboCard
PAMDB000615NADPHMetaboCard
GO Classification:
Function
binding
catalytic activity
oxidoreductase activity
Process
metabolic process
oxidation reduction
Gene Properties
Locus tag: PA4907
Strand: -
Entrez Gene ID: 878002
Accession: NP_253594.1
GI: 15600100
Sequence start: 5505848
Sequence End: 5506609
Sequence Length: 761
Gene Sequence: 
>PA4907
ATGTCGTCCACCCTGTTCATCACCGGCGCCACCTCAGGCTTCGGCGAAGCCTGCGCCCGTCGTTTCGCCGAGGCCGGCTGGTCGCTGGTGCTCACCGGCCGTCGCGAGGAGCGTCTGCAAGCCCTGGCCGGTGAGCTTTCGGCGAAGACCCGGGTGTTGCCGCTGACCCTGGACGTGCGCGACCGCGCGGCGATGAGCGCGGCCGTGGACAACCTGCCGGAAGAGTTCGCCACCCTGCGCGGCCTGATCAACAACGCCGGCCTGGCGCTGGGCACCGACCCGGCGCAGTCCTGCGACCTGGACGACTGGGACACCATGGTCGACACCAACATCAAGGGCCTGCTCTACAGCACGCGCCTGCTGCTGCCGCGGCTGATCGCCCACGGCGCCGGGGCGAGCATCGTCAACCTGGGTTCGGTGGCCGGCAAGTGGCCCTATCCGGGTAGCCATGTCTACGGCGGCACCAAGGCCTTCGTCGAGCAATTCTCCCTGAACCTGCGTTGCGACCTGCAGGGCACCGGGGTGCGCGTGACCAACCTCGAGCCGGGGCTGTGCGAGAGCGAGTTCTCCCTGGTCCGCTTCGGCGGCGACCAGGCGCGCTACGACAAGACCTACGCCGGGGCCCATCCGATCCAGCCGGAAGACATCGCCGAGACCATCTTCTGGATCATGAACCAGCCCGCCCACCTGAACATCAACAGCCTCGAGATCATGCCGGTGAGCCAGTCCTGGGCCGGCTTCGCCATCCACCGCGAAAGCTGA
Protein Properties
Protein Residues: 253
Protein Molecular Weight: 27.4 kDa
Protein Theoretical pI: 5.1
Hydropathicity (GRAVY score): -0.047
Charge at pH 7 (predicted): -5.92
Protein Sequence: 
>PA4907
MSSTLFITGATSGFGEACARRFAEAGWSLVLTGRREERLQALAGELSAKTRVLPLTLDVRDRAAMSAAVDNLPEEFATLRGLINNAGLALGTDPAQSCDLDDWDTMVDTNIKGLLYSTRLLLPRLIAHGAGASIVNLGSVAGKWPYPGSHVYGGTKAFVEQFSLNLRCDLQGTGVRVTNLEPGLCESEFSLVRFGGDQARYDKTYAGAHPIQPEDIAETIFWIMNQPAHLNINSLEIMPVSQSWAGFAIHRES
References
External Links:
Resource Link
Genome ID: PA4907
Entrez Gene ID: 878002
NCBI Protein ID: 15600100
General Reference: PaperBLAST - Find papers about PA4907 and its homologs