| Identification |
| Name: |
Formate dehydrogenase, nitrate-inducible, major subunit |
| Synonyms: |
- Anaerobic formate dehydrogenase major subunit
- Formate dehydrogenase-N subunit alpha
- FDH-N subunit alpha
|
| Gene Name: |
fdnG |
| Enzyme Class: |
|
| Biological Properties |
| General Function: |
Involved in formate dehydrogenase (NAD+) activity |
| Specific Function: |
Formate dehydrogenase allows E.coli to use formate as major electron donor during anaerobic respiration, when nitrate is used as electron acceptor. The alpha subunit forms the active site |
| Cellular Location: |
Periplasm |
| KEGG Pathways: |
|
| KEGG Reactions: |
|
| SMPDB Reactions: |
Not Available |
| PseudoCyc/BioCyc Reactions: |
|
| Complex Reactions: |
|
| Transports: |
Not Available |
| Metabolites: |
|
| GO Classification: |
| Component |
|---|
| cell part | | cytoplasm | | intracellular part | | Function |
|---|
| binding | | catalytic activity | | cation binding | | electron carrier activity | | formate dehydrogenase activity | | ion binding | | metal ion binding | | molybdenum ion binding | | oxidoreductase activity | | oxidoreductase activity, acting on the aldehyde or oxo group of donors | | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | | transition metal ion binding | | Process |
|---|
| cellular metabolic process | | cellular respiration | | energy derivation by oxidation of organic compounds | | generation of precursor metabolites and energy | | metabolic process | | oxidation reduction |
|
| Gene Properties |
| Locus tag: |
PA4812 |
| Strand: |
- |
| Entrez Gene ID: |
880124 |
| Accession: |
YP_003933614.1 |
| GI: |
308198350 |
| Sequence start: |
5398628 |
| Sequence End: |
5401708 |
| Sequence Length: |
3080 |
| Gene Sequence: |
>PA4812
ATGGATATGAACCGTCGGCAATTCTTCAAGGTCTGCGGTATAGGCCTTGGAGGATCGAGCCTTGCGGCGCTCGGGATGGCCCCCACGGAGGCCTTCGCCGACCAGGTCCGCCACTTCAAGCTGGCGCACACGGTCGAGACCCGCAACACCTGTACCTACTGTTCGGTCGGTTGCGGCCTGATCATGTACAGCCAGGGCGACGGCGCCAAGAACGTCGCGCAGAACATCATCCATATCGAGGGCGACGCCGACCATCCGGTCAACCGCGGCACCCTCTGCCCGAAAGGCGCCGGCCTGCTGGACTACATCCACAGCCCGAACCGCCTGAAGTATCCGGAAGTGCGCGAGGCCGGCTCCAGCGAGTGGAAGCGCATCGAGTGGGACGAAGCCCTCGAGCGCATCGCCAAGCTGATGAAGGAAGACCGCGACGCCAACTTCGTCGAGAAGAACGAGCAGGGCCAGACCGTCAACCGCTGGTTGACCACCGGCTTCCTCGCCGCGTCCGCCTCGTCCAACGAGGCCGGCTACATCACCCACAAGGTGATGCGCTCCCTCGGCATCCTGGGATTCGACAACCAGGCGCGTGTCTGACACGGCCCGACGGTGGCAAGTCTTGCCCCGACGTTTGGCCGTGGAGCCATGACCAACCACTGGACCGACATCAAGAATGCCGATTTGGTGCTGATCATGGGCGGCAACGCCGCCGAAGCCCACCCGTGCGGATTCAAATGGGTCACCGAAGCCAAGGCGCACAACAAGGCGCGGCTGCTGGTGGTCGATCCGCGTTTCACCCGTTCCGCCTCGGTCGCCGACTACTACGCGCCGATCCGGACCGGCACCGACATCGCCTTCCTCGGCGGCCTGATCAACTACCTGCTGGAAAACGACAAGATCCAGCACGAATACGTGCGCAACTACACCGATGTCTCGTTCATCGTGAAGGAAGGCTTCAGCTTCGAGGACGGCCTGTTCAACGGCTACGATGCCGAGAAGCGGACCTACCCGGACAAGTCCTCCTGGGGCTACGAGATCGGTGAGGACGGCTATGCCAAGGTCGACCCGACCCTGACCCACCCGCGCTGCGTGTTCAACCTGCTCAAGCAGCACTACAGCCGCTACACCCCGGACGTGGTGAGCAACATCTGCGGTACGCCGAAGGACATGATGCTCAAGGTCTGGGCGGAAATCGCCGAGACCTCCAAGCCGGGCAAGGTCATGACCATCATGTACGCCCTGGGCTGGACCCAGCACTCGGTAGGCGCGCAGATGATCCGCACCGGCGCGATGGTCCAGCTGCTGCTGGGCAACATCGGCATGCCCGGCGGCGGCATGAACGCCCTGCGCGGCCACTCCAACATCCAGGGCCTGACCGACCTCGGCCTGCTGTCCAACTCGCTGCCGGGCTACCTGACCCTGGCGATGGACGCCGAGCAGGACTACGACGCCTACATCGCCAAGCGCACGGCCAAGCCGCTGCGCCCGGGACAGCTGTCCTACTGGCAGAACTACGGCAAGTTCCACGTCAGCCTGATGAAGGCCTGGTTCGGCAAGTCGGCGACCAAGGAAAACAACTGGTGCTACGACTGGCTGCCCAAGCTCGACATGCCGGGCGCCGGCTACGACGTGCTGCGCTACTTCGACATGATGTACCAGGGCAAGGTCAACGGTTACTTCTGCCAGGGCTTCAACCCCATCGCCTCGTTCCCCAACAAGGCCAAGGTCGGCGCCGCGCTGGCGCGCCTGAAGTGGATGGTGGTGATGGACCCGCTGGTGACCGAGACCTCGGAGTTCTGGCGCAACGTCGGCGAGTACAACGACGTCGACACCGCCAGCATCAAGACCACGGTGTTCCGCCTGCCCACCTCCTGCTTCGCCGAGGAAGACGGCTCGATCGTCAACAGCGGCCGCTGGTTGCAGTGGCACTGGAAGGGCGCCGAGCCGCCGGGCCAGGCGCGTCCGGACATCGCCATCATGGCCGGGCTGTTCCACCGCCTGCGCGAGATGTACCGCAAGGACGGCGGGGCCTTCCCCGACCCGATCCTCGGCCTCGACTGGTCCTACCTCAAGCCCGACGAACCGGGCCCGGACGAACTGGCCCGGGAGTTCAACGGCAAGGCCCTGAGCGACCTGGTCGACCCGGCCAACGGCATGATCCTGGCCAAGGCCGGCGAGCAGTTGCCGGGCTTTGCCCTGCTGCGCGACGACGGCAGCACGGCGAGCGGCTGCTGGATCTTCGCCGGCTCCTGGACCCAGCAGGGCAACCAGATGGGCCGCCGCGACAACAGCGACCCCTACGGCATGGGCCAGACCCTCGGCTGGGCCTGGGCCTGGCCGGCGAACCGGCGGATTCTCTACAACCGCGCCTCGGCCGACGTCAGCGGCAAGCCGTGGGACCCGGAGAAGAAGCGCCTGGTGTGGTGGAACGGCAAGTCCTGGGGCGGCACCGACGTGCCCGACTACAAGGCCGACGTACCGCCGGAAGCCGGGATGAACCCGTTCATCATGAACCCCGAAGGGGTGGCCCGCCTGTTCGCCGTCGACAAGATGGCCGAAGGCCCGTTCCCCGAGCACTACGAGCCGTTCGAGACGCCGATCGGGGTGAACCCCTTGCACCGCGACAACCGCAAGGCGATCAGCAACCCGGCGGCACGGGTGTTCAAGAACGACATGGAACTGTTCGGCACGGCCGACGAGTTCCCCTACGCGGCGACCACCTACCGGCTCACCGAGCACTTCCACTACTGGACCAAGCACTGCCGGCTGAATGCGATCACCCAGCCCGAGCAGTTCGTCGAGATCGGCGAGGCGCTGGCCAAGGAGCTGGGCATCAATGCCGGCGACAAGGTCAAGGTCTCCTCCAACCGCGGCTACATCAAGGCGGTGGCGGTGGTGACCAAGCGCATCCGCCCGCTGCAGGTGGACGGTAAGACCGTGCACCACGTCGGCATCCCGATCCACTGGGGCTTCGCCGGCATGGCGCGCAACGGCTTCCTGGCCAACACCCTGACCCCCTTCGTGGGCGACGGGAATACCCAGACGCCGGAGTTCAAGTCGTTCCTGGTCAACGTGGAAAAGGCGTGA |
| Protein Properties |
| Protein Residues: |
1026 |
| Protein Molecular Weight: |
104.7 kDa |
| Protein Theoretical pI: |
12.81 |
| Hydropathicity (GRAVY score): |
-0.909 |
| Charge at pH 7 (predicted): |
170.87 |
| Protein Sequence: |
>PA4812
MDMNRRQFFKVCGIGLGGSSLAALGMAPTEAFADQVRHFKLAHTVETRNTCTYCSVGCGLIMYSQGDGAKNVAQNIIHIEGDADHPVNRGTLCPKGAGLLDYIHSPNRLKYPEVREAGSSEWKRIEWDEALERIAKLMKEDRDANFVEKNEQGQTVNRWLTTGFLAASASSNEAGYITHKVMRSLGILGFDNQARV*HGPTVASLAPTFGRGAMTNHWTDIKNADLVLIMGGNAAEAHPCGFKWVTEAKAHNKARLLVVDPRFTRSASVADYYAPIRTGTDIAFLGGLINYLLENDKIQHEYVRNYTDVSFIVKEGFSFEDGLFNGYDAEKRTYPDKSSWGYEIGEDGYAKVDPTLTHPRCVFNLLKQHYSRYTPDVVSNICGTPKDMMLKVWAEIAETSKPGKVMTIMYALGWTQHSVGAQMIRTGAMVQLLLGNIGMPGGGMNALRGHSNIQGLTDLGLLSNSLPGYLTLAMDAEQDYDAYIAKRTAKPLRPGQLSYWQNYGKFHVSLMKAWFGKSATKENNWCYDWLPKLDMPGAGYDVLRYFDMMYQGKVNGYFCQGFNPIASFPNKAKVGAALARLKWMVVMDPLVTETSEFWRNVGEYNDVDTASIKTTVFRLPTSCFAEEDGSIVNSGRWLQWHWKGAEPPGQARPDIAIMAGLFHRLREMYRKDGGAFPDPILGLDWSYLKPDEPGPDELAREFNGKALSDLVDPANGMILAKAGEQLPGFALLRDDGSTASGCWIFAGSWTQQGNQMGRRDNSDPYGMGQTLGWAWAWPANRRILYNRASADVSGKPWDPEKKRLVWWNGKSWGGTDVPDYKADVPPEAGMNPFIMNPEGVARLFAVDKMAEGPFPEHYEPFETPIGVNPLHRDNRKAISNPAARVFKNDMELFGTADEFPYAATTYRLTEHFHYWTKHCRLNAITQPEQFVEIGEALAKELGINAGDKVKVSSNRGYIKAVAVVTKRIRPLQVDGKTVHHVGIPIHWGFAGMARNGFLANTLTPFVGDGNTQTPEFKSFLVNVEKA |
| References |
| External Links: |
|
| General Reference: |
PaperBLAST - Find papers about PA4812 and its homologs
|
