Glyceraldehyde-3-phosphate dehydrogenase A (PA3195)

Identification
Name: Glyceraldehyde-3-phosphate dehydrogenase A
Synonyms:
  • GAPDH-A
Gene Name: gapA
Enzyme Class:
Biological Properties
General Function: Involved in oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
Specific Function: D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = 3-phospho-D-glyceroyl phosphate + NADH
Cellular Location: Cytoplasm
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb+Thumb ↔ Thumb+2 Thumb+Thumb
D-Erythrose 4-phosphate + Water + NAD ↔ 4-Phospho-D-erythronate + 2 Hydrogen ion + NADH
ReactionCard
Thumb+Thumb+Thumb ↔ Thumb+Thumb+Thumb+Thumb
D-Glyceraldehyde 3-phosphate + NAD + Phosphate ↔ Glyceric acid 1,3-biphosphate + Hydrogen ion + NADH + 3-phospho-D-glyceroyl phosphate
ReactionCard
Thumb+Thumb+Thumb ↔ Thumb+Thumb+Thumb
D-Glyceraldehyde 3-phosphate + Phosphate + NAD ↔ Glyceric acid 1,3-biphosphate + NADH + Hydrogen ion
ReactionCard
Thumb+Thumb+Thumb ↔ Thumb+Thumb+Thumb
D-Glyceraldehyde 3-phosphate + Phosphate + NAD ↔ Hydrogen ion + Glyceric acid 1,3-biphosphate + NADH
ReactionCard
SMPDB Reactions:
D-Glyceraldehyde 3-phosphate+Thumb+Thumb+Thumb → Glyceric acid 1,3-biphosphate+Thumb+Thumb+Thumb
D-Glyceraldehyde 3-phosphate + NAD + Phosphate + D-Glyceraldehyde 3-phosphate → Glyceric acid 1,3-biphosphate + NADH + Hydrogen ion + Glyceric acid 1,3-biphosphate
ReactionCard
Glyceric acid 1,3-biphosphate+Thumb+Thumb+Thumb → Thumb+Thumb+D-Glyceraldehyde 3-phosphate+Thumb
Glyceric acid 1,3-biphosphate + NADH + Hydrogen ion + Glyceric acid 1,3-biphosphate → NAD + Phosphate + D-Glyceraldehyde 3-phosphate + D-Glyceraldehyde 3-phosphate
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb+Thumb+Thumb ↔ Thumb+2 Thumb+Thumb
D-Erythrose 4-phosphate + Water + NAD ↔ 4-Phospho-D-erythronate + 2 Hydrogen ion + NADH
ReactionCard
Thumb+Thumb+Thumb ↔ Thumb+Thumb+Thumb+Thumb
D-Glyceraldehyde 3-phosphate + NAD + Phosphate ↔ Glyceric acid 1,3-biphosphate + Hydrogen ion + NADH + 3-phospho-D-glyceroyl phosphate
ReactionCard
Thumb+Thumb+Thumb ↔ Thumb+Thumb+Thumb
D-Glyceraldehyde 3-phosphate + Phosphate + NAD ↔ Hydrogen ion + Glyceric acid 1,3-biphosphate + NADH
ReactionCard
Complex Reactions:
Thumb+Thumb+Thumb → Thumb+Thumb
D-Glyceraldehyde 3-phosphate + Inorganic phosphate + NAD → 3-phospho-D-glyceroyl phosphate + NADH
ReactionCard
Thumb+Thumb+Thumb → Thumb+Thumb
D-Glyceraldehyde 3-phosphate + Inorganic phosphate + NAD → 3-phospho-D-glyceroyl phosphate + NADH
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB0035313-phospho-D-glyceroyl phosphateMetaboCard
PAMDB0009434-Phospho-D-erythronateMetaboCard
PAMDB000460D-Erythrose 4-phosphateMetaboCard
PAMDB000257D-Glyceraldehyde 3-phosphateMetaboCard
PAMDB000317Glyceric acid 1,3-biphosphateMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB001776Inorganic phosphateMetaboCard
PAMDB000197NADMetaboCard
PAMDB000398NADHMetaboCard
PAMDB000383PhosphateMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Function
binding
catalytic activity
glyceraldehyde-3-phosphate dehydrogenase activity
NAD or NADH binding
nucleotide binding
oxidoreductase activity
oxidoreductase activity, acting on the aldehyde or oxo group of donors
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
Process
alcohol metabolic process
glucose metabolic process
hexose metabolic process
metabolic process
monosaccharide metabolic process
oxidation reduction
small molecule metabolic process
Gene Properties
Locus tag: PA3195
Strand: +
Entrez Gene ID: 882829
Accession: NP_251885.1
GI: 15598391
Sequence start: 3587433
Sequence End: 3588437
Sequence Length: 1004
Gene Sequence: 
>PA3195
ATGACTATCCGCCTGGCCATCAACGGCTTCGGTCGCATCGGCCGAAACGTTCTTCGCGCCCTGTATACCGGCCACTACCGCGAACAGTTGCAGGTAGTGGCGATCAATGACCTCGGCGACGCCGCGGTCAACGCCCACCTGTTCCAGTACGACAGCGTCCATGGACACTTTCCCGGCGAGGTCGAGCACGATGCCGAAAGCCTGCGGGTGATGGGCGACCGCATCGCCGTCAGCGCCATCCGCAACCCGGCGGAACTGCCCTGGAAGAGCCTCGGCGTGGACATCGTGCTCGAGTGCACGGGGCTCTTCACCAGCCGCGACAAAGCCGCTGCCCACCTGCAGGCCGGCGCCGGCAAGGTGCTGATCTCGGCGCCCGGCAAGGATGTCGAAGCCACCGTGGTCTACGGCGTCAACCACGAGGTGCTGCGCGCCTCCCATCGGATCGTCTCGAACGCCTCCTGCACCACCAACTGCCTGGCACCGGTGGCCCAGGTGCTGCATCGCGAGCTGGGCATCGAGCACGGCCTGATGACCACCATCCATGCCTACACCAACGACCAGAACCTCTCCGACGTGTACCACCCGGACCTGTACCGCGCACGTTCGGCGACCCAGTCGATGATCCCCACCAAGACCGGCGCCGCCGAGGCGGTCGGCCTGGTCCTGCCGGAACTCGCCGGCAAGCTTACCGGGCTGGCGGTGCGGGTGCCGGTGATCAACGTGTCGCTGGTCGATCTCACCGTGCAGGTGGCCCGGGATACCAGCGTAGACGAGGTCAACCGCCTGCTGCGCGAAGCCAGCGAGGGCTCTCCGGTGCTCGGCTACAACACCCAGCCGCTGGTGTCGGTGGATTTCAATCACGACCCGCGCTCGTCGATCTTCGACGCCAACCACACCAAGGTCAGCGGCCGGCTGGTCAAGGCGATGGCCTGGTACGACAACGAGTGGGGCTTCTCCAACCGCATGCTGGACAGCGCCCTGGCGCTGGCCGCCGCCCGCGACTGA
Protein Properties
Protein Residues: 334
Protein Molecular Weight: 36.2 kDa
Protein Theoretical pI: 6.63
Hydropathicity (GRAVY score): -0.028
Charge at pH 7 (predicted): -2.73
Protein Sequence: 
>PA3195
MTIRLAINGFGRIGRNVLRALYTGHYREQLQVVAINDLGDAAVNAHLFQYDSVHGHFPGEVEHDAESLRVMGDRIAVSAIRNPAELPWKSLGVDIVLECTGLFTSRDKAAAHLQAGAGKVLISAPGKDVEATVVYGVNHEVLRASHRIVSNASCTTNCLAPVAQVLHRELGIEHGLMTTIHAYTNDQNLSDVYHPDLYRARSATQSMIPTKTGAAEAVGLVLPELAGKLTGLAVRVPVINVSLVDLTVQVARDTSVDEVNRLLREASEGSPVLGYNTQPLVSVDFNHDPRSSIFDANHTKVSGRLVKAMAWYDNEWGFSNRMLDSALALAAARD
References
External Links:
Resource Link
Genome ID: PA3195
Entrez Gene ID: 882829
NCBI Protein ID: 15598391
General Reference: PaperBLAST - Find papers about PA3195 and its homologs