Mannitol-1-phosphate 5-dehydrogenase (PA2342)

Identification
Name: Mannitol-1-phosphate 5-dehydrogenase
Synonyms: Not Available
Gene Name: mtlD
Enzyme Class:
Biological Properties
General Function: Involved in oxidation-reduction process
Specific Function: D-mannitol 1-phosphate + NAD(+) = D-fructose 6-phosphate + NADH
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb ↔ Thumb+Thumb+Thumb
Sorbitol-6-phosphate + NAD ↔ beta-D-Fructose 6-phosphate + NADH + Hydrogen ion
ReactionCard
Thumb+Thumb ↔ Thumb+Thumb+Thumb
Mannitol 1-phosphate + NAD ↔ Fructose 6-phosphate + NADH + Hydrogen ion
ReactionCard
SMPDB Reactions:
Fructose 6-phosphate+Thumb+Thumb+Thumb ↔ Thumb+Thumb
Fructose 6-phosphate + NADH + Hydrogen ion + Fructose 6-phosphate ↔ NAD + Mannitol 1-phosphate
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb+Thumb ↔ Thumb+Thumb+Thumb
NAD + Sorbitol-6-phosphate ↔ Fructose 6-phosphate + Hydrogen ion + NADH
ReactionCard
Thumb+Thumb ↔ Thumb+Thumb+Thumb
Sorbitol-6-phosphate + NAD ↔ Fructose 6-phosphate + Hydrogen ion + NADH
ReactionCard
Thumb+Thumb ↔ Thumb+Thumb+Thumb
Sorbitol-6-phosphate + NAD ↔ Hydrogen ion + Fructose 6-phosphate + NADH
ReactionCard
Complex Reactions:
Thumb+Thumb → Thumb+Thumb
Mannitol 1-phosphate + NAD → Fructose 6-phosphate + NADH
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000547beta-D-Fructose 6-phosphateMetaboCard
PAMDB000047Fructose 6-phosphateMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB001829Mannitol 1-phosphateMetaboCard
PAMDB000197NADMetaboCard
PAMDB000398NADHMetaboCard
PAMDB000371Sorbitol-6-phosphateMetaboCard
GO Classification:
Function
binding
catalytic activity
coenzyme binding
cofactor binding
oxidoreductase activity
Process
metabolic process
oxidation reduction
Gene Properties
Locus tag: PA2342
Strand: +
Entrez Gene ID: 879998
Accession: NP_251032.1
GI: 15597538
Sequence start: 2586434
Sequence End: 2587909
Sequence Length: 1475
Gene Sequence: 
>PA2342
ATGAAACTCAACCGGCAGCACCTCCCCCTGCTGGCGACCGCTGTCGCCCGCCCGTCCTACGACCCCGCGCAACTGCGCCAGGGCATCGTCCACATCGGCGTCGGCGGCTTCCACCGCGCGCACCAGGCGGCCTACACCGACGCCCTGATGAACCGCGGCGAAGCCCTCGACTGGGCTATCTGCGGCGCCGGCCTGCGCAGCGACGACCGCGCCATGCACGACGCCCTGGCCGCCCAGGACTACCTCTACACCCTCTACGAGCTGGGCGACCAACCGGACACCGAGGTCCGCGTGATCGGCGCCATCAGCGGCATGCTGCTCGCCGAGGACGGCGCCGAGGCGCTGCTGGAAAAACTTGCCGAGCCGGCCATCCGCATCGTCTCGCTGACCATCACCGAAGGCGGCTACTGCATCGACGATGGCAGCGGCGAGTTCCTCGCCGAGTTGCCGCTGGTGCGCCACGACCTGGCCAACCCGCGGACCCCGCGCGGGGTCTTCGGCTTTCTCTGCGAGGCTCTGCGGCGGCGCCGCGACACAGGCGTGCCGGCGTTCACCGTGATGTCCTGCGACAACCTCCCGCATAACGGCGAGGTGGCGCGCAAGGCGCTGCTGGCCTTCGCCGAACGGCTCGACCCGGGGCTGGCGCGCTGGATCGCGACGCACGTCAGCTTTCCCAACGCCATGGTCGACCGCATCACCCCGATGACCAGCCCCGCCCACCGCCGCCAACTGGCCCAACGGCACGACGTGGAAGACGCCTGGCCGGTGGTCTGCGAACCCTTCGTGCAATGGGTGCTGGAAGATCGTTTCAGCGCTGGGCGCCCGGCCTGGGAAAAGGTCGGCGTGCAGTTCACCGACGACGTCACGCCCTACGAGGAGATGAAGATCGGCCTGCTCAACGGCAGCCACCTGGCGCTCACCTACCTGGGCTTCCTGCGCGGCTACCGCTTCGTCCACGAGACCCTCGGCGACCCGCTGCTGCGCCGCTACGTGCGGGCCTTCATGGACCGCGACGTGGCCCCGCTGCTGGCACCGGTACCGGGGATCGACCTGGAACGCTACAAGGACAGCCTGGTCGAGCGCTTCGCCAACCGCGCCATCGCCGACCAACTGGAACGGGTCTGCTCGGACGGCTCGTCGAAGTTTCCCAAGTTCATCGTCCCCACCGCCAATCGGCTGATCGCCGCCGGCCGGCCGCTGGAACGGGTGGCCCTGGTGGTGGCGGCCTGGGCGCTGTACCTGGGCGGGGTCGACGAGCATGGCGAACGCTACCCGATTCCCGATCCGCGCGCCGCCGAATGCCAGGCGCTGGTTGCCGAACGCCACGGCCTGGGCCGGCGCCTGCTCGGCGTGGAGACCGTGTTCGGCCCGGCGATCCCGGCCTCGGCGGCCTTCGTCGAGGCCTTCGAGCGGCTCTACGACAGCCTGCGCCGACACGGCGTCAGCGAAACCCTGCGCCAGGTACTCGGCGAATGA
Protein Properties
Protein Residues: 491
Protein Molecular Weight: 54.3 kDa
Protein Theoretical pI: 6.24
Hydropathicity (GRAVY score): -0.107
Charge at pH 7 (predicted): -6.58
Protein Sequence: 
>PA2342
MKLNRQHLPLLATAVARPSYDPAQLRQGIVHIGVGGFHRAHQAAYTDALMNRGEALDWAICGAGLRSDDRAMHDALAAQDYLYTLYELGDQPDTEVRVIGAISGMLLAEDGAEALLEKLAEPAIRIVSLTITEGGYCIDDGSGEFLAELPLVRHDLANPRTPRGVFGFLCEALRRRRDTGVPAFTVMSCDNLPHNGEVARKALLAFAERLDPGLARWIATHVSFPNAMVDRITPMTSPAHRRQLAQRHDVEDAWPVVCEPFVQWVLEDRFSAGRPAWEKVGVQFTDDVTPYEEMKIGLLNGSHLALTYLGFLRGYRFVHETLGDPLLRRYVRAFMDRDVAPLLAPVPGIDLERYKDSLVERFANRAIADQLERVCSDGSSKFPKFIVPTANRLIAAGRPLERVALVVAAWALYLGGVDEHGERYPIPDPRAAECQALVAERHGLGRRLLGVETVFGPAIPASAAFVEAFERLYDSLRRHGVSETLRQVLGE
References
External Links:
Resource Link
Genome ID: PA2342
Entrez Gene ID: 879998
NCBI Protein ID: 15597538
General Reference: PaperBLAST - Find papers about PA2342 and its homologs