Glycerol-3-phosphate dehydrogenase [NAD(P)+] (PA1614)

Identification
Name: Glycerol-3-phosphate dehydrogenase [NAD(P)+]
Synonyms:
  • NAD(P)H-dependent glycerol-3-phosphate dehydrogenase
Gene Name: gpsA
Enzyme Class:
Biological Properties
General Function: Involved in oxidation-reduction process
Specific Function: sn-glycerol 3-phosphate + NAD(P)(+) = glycerone phosphate + NAD(P)H
Cellular Location: Cytoplasm (Probable)
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb ↔ Thumb+Thumb+Thumb
Glycerol 3-phosphate + NADP ↔ Dihydroxyacetone phosphate + Hydrogen ion + NADPH
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Thumb+Thumb ↔ Thumb+Thumb+Thumb
Glycerol 3-phosphate + NAD ↔ Dihydroxyacetone phosphate + NADH + Hydrogen ion
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Thumb+Thumb ↔ Thumb+Thumb+Thumb
Glycerol 3-phosphate + NADP ↔ Dihydroxyacetone phosphate + NADPH + Hydrogen ion
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Thumb+Thumb+Thumb ↔ Thumb+Thumb+Thumb+Thumb
Glycerol 3-phosphate + NAD + NADP ↔ Dihydroxyacetone phosphate + NADH + NADPH + Hydrogen ion
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SMPDB Reactions:
Thumb+Thumb+NADPH+Thumb → Thumb+Thumb
Dihydroxyacetone phosphate + Hydrogen ion + NADPH + NADPH → NADP + Glycerol 3-phosphate
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Thumb+Thumb → Thumb+Thumb
Glycerol 3-phosphate + Ubiquinone-1 → Dihydroxyacetone phosphate + Ubiquinol-1
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PseudoCyc/BioCyc Reactions:
Thumb+Thumb ↔ Thumb+Thumb+Thumb
Glycerol 3-phosphate + NADP ↔ Dihydroxyacetone phosphate + Hydrogen ion + NADPH
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Thumb+Thumb ↔ Thumb+Thumb+Thumb
Glycerol 3-phosphate + NAD ↔ Dihydroxyacetone phosphate + NADH + Hydrogen ion
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Thumb+Thumb ↔ Thumb+Thumb+Thumb
Glycerol 3-phosphate + NADP ↔ Dihydroxyacetone phosphate + NADPH + Hydrogen ion
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Thumb+NAD(P)(+) → Thumb+NAD(P)H
Glycerol 3-phosphate + NAD(P)(+) → Dihydroxyacetone phosphate + NAD(P)H
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Thumb+Thumb+Thumb ↔ Thumb+Thumb+Thumb+Thumb
Glycerol 3-phosphate + NAD + NADP ↔ Dihydroxyacetone phosphate + NADH + NADPH + Hydrogen ion
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Thumb+Thumb+NADPH+Thumb → Thumb+Thumb
Dihydroxyacetone phosphate + Hydrogen ion + NADPH + NADPH → NADP + Glycerol 3-phosphate
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Thumb+Thumb → Thumb+Thumb
Glycerol 3-phosphate + Ubiquinone-1 → Dihydroxyacetone phosphate + Ubiquinol-1
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Thumb
sn-glycerol 3-phosphate + NAD(P)+ ↔ glycerone phosphate + NAD(P)H + H+
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PAMDB110409+PAMDB110542 → PAMDB110137+PAMDB110540+PAMDB001633
sn-glycerol 3-phosphate + NAD+ → glycerone phosphate + NADH + Hydrogen ion
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Complex Reactions:
Thumb+NAD(P)(+) → Thumb+NAD(P)H
Glycerol 3-phosphate + NAD(P)(+) → Dihydroxyacetone phosphate + NAD(P)H
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Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000395Dihydroxyacetone phosphateMetaboCard
PAMDB000049Glycerol 3-phosphateMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000197NADMetaboCard
PAMDB000398NADHMetaboCard
PAMDB000089NADPMetaboCard
PAMDB000615NADPHMetaboCard
PAMDB001968Ubiquinol-1MetaboCard
PAMDB001833Ubiquinone-1MetaboCard
GO Classification:
Component
cell part
cytoplasm
glycerol-3-phosphate dehydrogenase complex
intracellular part
macromolecular complex
protein complex
Function
binding
catalytic activity
coenzyme binding
cofactor binding
glycerol-3-phosphate dehydrogenase [NAD+] activity
NAD or NADH binding
nucleotide binding
oxidoreductase activity
oxidoreductase activity, acting on CH-OH group of donors
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Process
alcohol metabolic process
alditol metabolic process
carbohydrate metabolic process
glycerol metabolic process
glycerol-3-phosphate catabolic process
glycerol-3-phosphate metabolic process
metabolic process
oxidation reduction
polyol metabolic process
primary metabolic process
small molecule metabolic process
Gene Properties
Locus tag: PA1614
Strand: +
Entrez Gene ID: 881904
Accession: NP_250305.1
GI: 15596811
Sequence start: 1758748
Sequence End: 1759770
Sequence Length: 1022
Gene Sequence: 
>PA1614
ATGACAGAGCAGCAACCGATTGCCGTGCTCGGCGGCGGCAGTTTCGGCACCGCCATCGCCAACCTGCTGGCCGAGAACGGCCAGGCGGTCCGCCAGTGGATGCGCGACCCGGAACAGGCCGAGGCGATCCGCACACGACGCGAGAACCCGCGCTACCTGAAAGGGGTCAAGGTGCATCCCGGAGTCGACCCGGTCACCGACCTGGAGCGCACCCTGGCCGATTGCCAACTGATCTTCGTCGCCTTGCCCTCCAGCGCCCTGCGCAAGGTGCTGCAACCACACCAGGCGGCATTGACGGACAAGCTGCTGGTGAGCCTGACCAAGGGCATCGAGGCGCACACCTTCAAGCTGATGAGTGAGATCCTCGAGGAAATCGCCCCGCAAGCCCGCATCGGGGTGATTTCCGGCCCGAACCTGGCGCGCGAGATCGCAGAGCACGAGCTGACCGCCACGGTGGTCGCCAGCGAGGACGACGAGCTGTGCGCCCGCGTCCAGGCGGCCCTGCACGGCCGCACCTTCCGCGTCTACGCCAGCCGCGACCGCTTCGGCGTGGAACTCGGCGGTGCGCTGAAGAACGTCTACGCGATCATGGCCGGCCTGGCCGCGGCGATGGACATGGGCGAGAACACCCGCAGCATGCTGATCACCCGCGCGCTGGCGGAAATGACCCGGTTCGCCGTCAAGCTCGGTGCCAACCCGATGACCTTTCTCGGCCTCGCCGGCGTCGGCGACCTGATCGTCACCTGTTCCTCGCCGAAGAGCCGCAACTACCAGGTCGGCCACGCCCTCGGCGAGGGGCTCAGCCTGGAGGAGGCGGTATCGCGCATGGGCGAGACCGCGGAGGGTGTGAACACTCTCAAGGTACTCAAGGAAAAGTCCGACGAGATGCAGGTGTACATGCCGCTGGTCGCCGGTCTCCATGCGATCCTCTTCGAAGGCCGCACCCTGGCGCAGGTCATCCAGTTGCTGATGCGCGGCGAGCCGAAGACCGACGTCGATTTCATTCCCACCACCGGCTTCTGA
Protein Properties
Protein Residues: 340
Protein Molecular Weight: 36.8 kDa
Protein Theoretical pI: 6.18
Hydropathicity (GRAVY score): 0.024
Charge at pH 7 (predicted): -3.4
Protein Sequence: 
>PA1614
MTEQQPIAVLGGGSFGTAIANLLAENGQAVRQWMRDPEQAEAIRTRRENPRYLKGVKVHPGVDPVTDLERTLADCQLIFVALPSSALRKVLQPHQAALTDKLLVSLTKGIEAHTFKLMSEILEEIAPQARIGVISGPNLAREIAEHELTATVVASEDDELCARVQAALHGRTFRVYASRDRFGVELGGALKNVYAIMAGLAAAMDMGENTRSMLITRALAEMTRFAVKLGANPMTFLGLAGVGDLIVTCSSPKSRNYQVGHALGEGLSLEEAVSRMGETAEGVNTLKVLKEKSDEMQVYMPLVAGLHAILFEGRTLAQVIQLLMRGEPKTDVDFIPTTGF
References
External Links:
Resource Link
Genome ID: PA1614
Entrez Gene ID: 881904
NCBI Protein ID: 15596811
General Reference: PaperBLAST - Find papers about PA1614 and its homologs