Cytochrome o ubiquinol oxidase subunit 3 (PA1319)

Identification
Name: Cytochrome o ubiquinol oxidase subunit 3
Synonyms:
  • Cytochrome o ubiquinol oxidase subunit III
  • Ubiquinol oxidase chain C
Gene Name: cyoC
Enzyme Class: Not Available
Biological Properties
General Function: Involved in heme-copper terminal oxidase activity
Specific Function: Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration
Cellular Location: Cell inner membrane; Multi-pass membrane protein
KEGG Pathways:
  • Oxidative phosphorylation PW000919
  • succinate to cytochrome bo oxidase electron transfer PWY0-1329
  • proline to cytochrome bo oxidase electron transfer PWY0-1544
  • NADH to cytochrome bo oxidase electron transfer PWY0-1335
    KEGG Reactions: Not Available
    SMPDB Reactions:
    Thumb+8 Thumb+2 Thumb → 2 Thumb+8 Thumb+2 Thumb
    Oxygen + 8 Hydrogen ion + 2 Ubiquinol-1 → 2 Water + 8 Hydrogen ion + 2 Ubiquinone-1
    ReactionCard
    PseudoCyc/BioCyc Reactions:
    Thumb+Thumb → Thumb+Thumb
    Ubiquinol-8 + Oxygen → Ubiquinone-8 + Water
    ReactionCard
    Thumb+8 Thumb+2 Thumb → 2 Thumb+8 Thumb+2 Thumb
    Oxygen + 8 Hydrogen ion + 2 Ubiquinol-1 → 2 Water + 8 Hydrogen ion + 2 Ubiquinone-1
    ReactionCard
    Thumb
    ubiquinol-8 + oxygen = ubiquinone-8 + H2O
    ReactionCard
    PAMDB001633+PAMDB000624+Ubiquinols → PAMDB000142+Ubiquinones+PAMDB001633
    Hydrogen ion + Oxygen + Ubiquinols → Water + Ubiquinones + Hydrogen ion
    ReactionCard
    Complex Reactions:
    2 Thumb+0.5 Thumb+Thumb → Thumb+Thumb+2 Thumb
    2 Hydrogen ion + 0.5 Oxygen + Ubiquinol-8 → Water + Ubiquinone-8 + 2 Hydrogen ion
    ReactionCard
    4 Thumb+0.5 Thumb+Thumb → Thumb+Thumb+4 Thumb
    4 Hydrogen ion + 0.5 Oxygen + Ubiquinol-8 → Water + Ubiquinone-8 + 4 Hydrogen ion
    ReactionCard
    Thumb+Thumb → Thumb+Thumb
    Ubiquinol-8 + Oxygen → Ubiquinone-8 + Water
    ReactionCard
    Transports: Not Available
    Metabolites:
    PAMDB IDNameView
    PAMDB001633Hydrogen ionMetaboCard
    PAMDB000624OxygenMetaboCard
    PAMDB001968Ubiquinol-1MetaboCard
    PAMDB000237Ubiquinol-8MetaboCard
    PAMDB001833Ubiquinone-1MetaboCard
    PAMDB001700Ubiquinone-8MetaboCard
    PAMDB000142WaterMetaboCard
    GO Classification:
    Component
    cell part
    membrane
    plasma membrane
    Function
    catalytic activity
    cytochrome-c oxidase activity
    heme-copper terminal oxidase activity
    oxidoreductase activity
    oxidoreductase activity, acting on diphenols and related substances as donors
    oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
    Process
    cellular metabolic process
    electron transport chain
    generation of precursor metabolites and energy
    metabolic process
    mitochondrial electron transport, cytochrome c to oxygen
    oxidation reduction
    respiratory electron transport chain
    Gene Properties
    Locus tag: PA1319
    Strand: +
    Entrez Gene ID: 881595
    Accession: NP_250010.1
    GI: 15596516
    Sequence start: 1431062
    Sequence End: 1431691
    Sequence Length: 629
    Gene Sequence: 
    >PA1319
ATGTCGACGGCAGTATTGAACAAGCATCTGGCCGACGCCCACGAAGTGGGCCACGACCACGATCATGCACACGATAGCGGCGGCAACACCGTATTCGGTTTCTGGCTCTACCTGATGACCGACTGCGTGCTGTTCGCCAGCGTCTTCGCCACCTACGCGGTGCTGGTTCACCACACCGCCGGCGGCCCCAGCGGCAAGGACATCTTCGAGCTGCCCTACGTGCTGGTGGAAACCGCCATCCTGCTGGTTTCCAGCTGCACCTACGGCCTGGCCATGCTCTCTGCGCACAAGGGCGCCAAGGGCCAGGCGATCGCCTGGCTCGGGGTCACCTTCCTGCTCGGCGCCGCGTTCATCGGGATGGAGATCAACGAGTTCCACCACCTGATCGCCGAAGGTTTCGGCCCGAGCCGCAGCGCCTTCCTGTCGTCCTTCTTCACCCTGGTCGGCATGCACGGCCTGCACGTCAGCGCCGGTCTGCTGTGGATGCTGGTGCTGATGGCGCAGATCTGGACCCGCGGCCTCACCGCGCAGAACAACACCCGGATGATGTGCCTGAGCCTGTTCTGGCACTTCCTCGACATCGTCTGGATCTGCGTCTTCACCGTCGTCTACCTGATGGGGGCCCTGTAA
    Protein Properties
    Protein Residues: 209
    Protein Molecular Weight: 22.8 kDa
    Protein Theoretical pI: 6.62
    Hydropathicity (GRAVY score): 0.695
    Charge at pH 7 (predicted): -2.77
    Protein Sequence: 
    >PA1319
MSTAVLNKHLADAHEVGHDHDHAHDSGGNTVFGFWLYLMTDCVLFASVFATYAVLVHHTAGGPSGKDIFELPYVLVETAILLVSSCTYGLAMLSAHKGAKGQAIAWLGVTFLLGAAFIGMEINEFHHLIAEGFGPSRSAFLSSFFTLVGMHGLHVSAGLLWMLVLMAQIWTRGLTAQNNTRMMCLSLFWHFLDIVWICVFTVVYLMGAL
    References
    External Links:
    Resource Link
    Genome ID: PA1319
    Entrez Gene ID: 881595
    NCBI Protein ID: 15596516
    General Reference: PaperBLAST - Find papers about PA1319 and its homologs