P. aeruginosa Metabolome Database Protein PA0999

Identification

Name:

PqsD

Synonyms:

Not Available

Gene Name:

pqsD

Enzyme Class:

EC 2.3.1.230

Biological Properties

General Function:

secondary metabolite biosynthetic process, fatty acid biosynthetic process, metabolic process, lipid biosynthetic process

Specific Function:

3-oxoacyl-[acyl-carrier-protein] synthase activity, transferase activity, transferring acyl groups other than amino-acyl groups, catalytic activity, transferase activity, transferring acyl groups

Cellular Location:

Cytoplasmic

KEGG Pathways:

4-hydroxy-2(1H)-quinolone biosynthesis PWY-6661
2-heptyl-3-hydroxy-4(1H)-quinolone biosynthesis PWY-6660
fatty acid biosynthesis initiation I PWY-4381
superpathway of fatty acids biosynthesis (E. coli) PWY-6285

KEGG Reactions:

→

Anthraniloyl-CoA + Malonyl-CoA → 2-aminobenzoylacetyl-CoA + Coenzyme A + CO2
ReactionCard

SMPDB Reactions:

Not Available

PseudoCyc/BioCyc Reactions:

anthraniloyl-CoA + malonyl-CoA + H⁺ → 4-hydroxy-2(1H)-quinolone + CO₂ + 2 coenzyme A
ReactionCard

anthraniloyl-CoA + 3-oxodecanoate + H⁺ → 2-heptyl-4(1H)-quinolone + CO₂ + coenzyme A + H₂O
ReactionCard

→

acetyl-CoA + Hydrogen ion → coenzyme A + Carbon dioxide
ReactionCard

Complex Reactions:

Not Available

Transports:

Not Available

Metabolites:

PAMDB ID	Name	View
PAMDB000284	Malonyl-CoA	MetaboCard
PAMDB001633	Hydrogen	MetaboCard
PAMDB100027	2-aminobenzoylacetyl-CoA	MetaboCard
PAMDB000381	Coenzyme A	MetaboCard
PAMDB000568	Carbon dioxide	MetaboCard

GO Classification:

Function
3-oxoacyl-[acyl-carrier-protein] synthase activity
transferase activity, transferring acyl groups other than amino-acyl groups
catalytic activity
transferase activity, transferring acyl groups
Process
secondary metabolite biosynthetic process
fatty acid biosynthetic process
metabolic process
lipid biosynthetic process

Gene Properties

Locus tag:

PA0999

Strand:

Entrez Gene ID:

880625

Accession:

NP_249690.1

GI:

15596196

Sequence start:

1081942

Sequence End:

1082955

Sequence Length:

1014

Gene Sequence:

>PA0999
ATGGGTAATCCGATCCTGGCCGGGCTGGGTTTCAGCCTGCCGAAACGCCAGGTCAGCAATCATGACCTGGTAGGGCGCATCAATACGTCGGACGAGTTCA TCGTCGAACGTACCGGCGTGCGCACCCGCTATCACGTCGAGCCGGAACAGGCGGTCAGCGCGCTGATGGTGCCGGCGGCGCGCCAGGCCATCGAGGCTGC CGGGCTGCTGCCGGAGGACATCGACCTGTTGCTGGTGAACACCCTGTCGCCGGACCACCACGACCCGTCCCAGGCCTGCCTGATCCAGCCGCTGCTGGGC CTGCGGCACATCCCGGTACTGGATATCCGGGCACAGTGCAGCGGGTTGCTGTACGGCTTGCAGATGGCTCGCGGGCAGATCCTCGCCGGGCTGGCACGGC ATGTCCTGGTGGTCTGCGGCGAGGTGCTGTCCAAGCGCATGGACTGTTCGGACCGCGGCCGCAACCTGTCGATCCTGCTCGGCGACGGTGCCGGCGCAGT GGTGGTCAGCGCCGGCGAGAGTCTCGAAGACGGACTGCTGGACCTGCGCCTGGGCGCCGACGGCAACTACTTCGACCTGCTGATGACCGCGGCGCCGGGT AGTGCCTCGCCGACCTTCCTCGACGAGAATGTCCTGCGCGAGGGCGGGGGCGAGTTCCTCATGCGCGGCCGGCCGATGTTCGAGCATGCCAGCCAGACCC TGGTACGGATCGCCGGCGAAATGCTCGCGGCCCATGAGCTGACCCTGGACGACATCGACCATGTGATCTGCCATCAACCGAACCTGCGCATCCTCGATGC GGTGCAGGAGCAACTGGGCATTCCCCAGCACAAGTTCGCGGTGACCGTGGATCGTCTGGGCAACATGGCTTCGGCCTCGACCCCGGTCACGCTGGCGATG TTCTGGCCGGACATCCAGCCGGGACAGCGGGTGCTGGTCCTGACCTACGGCTCCGGCGCGACCTGGGGCGCGGCGCTGTACCGCAAACCTGAGGAGGTGA ACCGGCCATGTTGA

Protein Properties

Protein Residues:

337

Protein Molecular Weight:

36.4 kDa

Protein Theoretical pI:

5.34

Hydropathicity (GRAVY score):

0.072

Charge at pH 7 (predicted):

-9.53

Protein Sequence:

>PA0999
MGNPILAGLGFSLPKRQVSNHDLVGRINTSDEFIVERTGVRTRYHVEPEQAVSALMVPAARQAIEAAGLLPEDIDLLLVNTLSPDHHDPSQACLIQPLLG LRHIPVLDIRAQCSGLLYGLQMARGQILAGLARHVLVVCGEVLSKRMDCSDRGRNLSILLGDGAGAVVVSAGESLEDGLLDLRLGADGNYFDLLMTAAPG SASPTFLDENVLREGGGEFLMRGRPMFEHASQTLVRIAGEMLAAHELTLDDIDHVICHQPNLRILDAVQEQLGIPQHKFAVTVDRLGNMASASTPVTLAM FWPDIQPGQRVLVLTYGSGATWGAALYRKPEEVNRPC

References

External Links:

Resource	Link
Genome ID:	PA0999
Entrez Gene ID:	880625
NCBI Protein ID:	15596196

General Reference:

PaperBLAST - Find papers about PA0999 and its homologs

PqsD (PA0999)