phenylalanine-4-hydroxylase phenylalanine 4-monooxygenase (PA0872)

Identification
Name: phenylalanine-4-hydroxylase phenylalanine 4-monooxygenase
Synonyms: Not Available
Gene Name: phhA
Enzyme Class: Not Available
Biological Properties
General Function: cellular amino acid metabolic process, tyrosine biosynthetic process, L-phenylalanine catabolic process, aromatic amino acid family metabolic process, oxidation-reduction process
Specific Function: phenylalanine 4-monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen, iron ion binding, monooxygenase activity
Cellular Location: Cytoplasmic
KEGG Pathways:
KEGG Reactions: Not Available
SMPDB Reactions: Not Available
PseudoCyc/BioCyc Reactions:
Thumb
tetrahydrobiopterin + L-phenylalanine + oxygen → L-tyrosine + 4α-hydroxy-tetrahydrobiopterin
ReactionCard
PAMDB000061+PAMDB120503+PAMDB000624 → CPD-14931+PAMDB000060
L-Phenylalanine + 10-formyl-tetrahydrofolate + Oxygen → CPD-14931 + L-Tyrosine
ReactionCard
TETRA-H-BIOPTERIN+PAMDB000061+PAMDB000624 → PAMDB120052+PAMDB000060+PAMDB000142
TETRA-H-BIOPTERIN + L-Phenylalanine + Oxygen → 6,7-dihydrobiopterin + L-Tyrosine + Water
ReactionCard
Complex Reactions: Not Available
Transports: Not Available
Metabolites: Not Available
GO Classification:
Function
phenylalanine 4-monooxygenase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
iron ion binding
monooxygenase activity
Process
cellular amino acid metabolic process
tyrosine biosynthetic process
L-phenylalanine catabolic process
aromatic amino acid family metabolic process
oxidation-reduction process
Gene Properties
Locus tag: PA0872
Strand: -
Entrez Gene ID: 879709
Accession: NP_249563.1
GI: 15596069
Sequence start: 952619
Sequence End: 953407
Sequence Length: 788
Gene Sequence: 
>PA0872
ATGAAAACGACGCAGTACGTGGCCCGCCAGCCCGACGACAACGGTTTCATCCACTATCCGGAAACCGAGCACCAGGTCTGGAATACCCTGATCACCCGGCAACTGAAGGTGATCGAAGGCCGCGCCTGTCAGGAATACCTCGACGGCATCGAACAGCTCGGCCTGCCCCACGAGCGGATCCCCCAGCTCGACGAGATCAACAGGGTTCTCCAGGCCACCACCGGCTGGCGCGTGGCGCGGGTTCCGGCGCTGATTCCGTTCCAGACCTTCTTCGAACTGCTGGCCAGCCAGCAATTCCCCGTCGCCACCTTCATCCGCACCCCGGAAGAACTGGACTACCTGCAGGAGCCGGACATCTTCCACGAGATCTTCGGCCACTGCCCACTGCTGACCAACCCCTGGTTCGCCGAGTTCACCCATACCTACGGCAAGCTCGGCCTCAAGGCGAGCAAGGAGGAACGCGTGTTCCTCGCCCGCCTGTACTGGATGACCATCGAGTTCGGCCTGGTCGAGACCGACCAGGGCAAGCGCATCTACGGCGGCGGCATCCTCTCCTCGCCGAAGGAGACCGTCTACAGCCTCTCCGACGAGCCGCTGCACCAGGCCTTCAATCCGCTGGAGGCGATGCGCACGCCCTACCGCATCGACATCCTGCAACCGCTCTATTTCGTCCTGCCCGACCTCAAGCGCCTGTTCCAACTGGCCCAGGAAGACATCATGGCGCTGGTCCACGAGGCCATGCGCCTGGGCCTGCACGCGCCGCTGTTCCCGCCCAAGCAGGCGGCCTGA
Protein Properties
Protein Residues: 262
Protein Molecular Weight: 30.3 kDa
Protein Theoretical pI: 5.57
Hydropathicity (GRAVY score): -0.224
Charge at pH 7 (predicted): -6.9
Protein Sequence: 
>PA0872
MKTTQYVARQPDDNGFIHYPETEHQVWNTLITRQLKVIEGRACQEYLDGIEQLGLPHERIPQLDEINRVLQATTGWRVARVPALIPFQTFFELLASQQFPVATFIRTPEELDYLQEPDIFHEIFGHCPLLTNPWFAEFTHTYGKLGLKASKEERVFLARLYWMTIEFGLVETDQGKRIYGGGILSSPKETVYSLSDEPLHQAFNPLEAMRTPYRIDILQPLYFVLPDLKRLFQLAQEDIMALVHEAMRLGLHAPLFPPKQAA
References
External Links:
Resource Link
Genome ID: PA0872
Entrez Gene ID: 879709
NCBI Protein ID: 15596069
General Reference: PaperBLAST - Find papers about PA0872 and its homologs