ATP synthase subunit beta (PA5554)

Identification
Name: ATP synthase subunit beta
Synonyms:
  • ATP synthase F1 sector subunit beta
  • F-ATPase subunit beta
Gene Name: atpD
Enzyme Class:
Biological Properties
General Function: Involved in nucleotide binding
Specific Function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Cellular Location: Cell inner membrane; Peripheral membrane protein
KEGG Pathways:
  • Oxidative phosphorylation PW000919
  • Photosynthesis pae00195
  • Methane metabolism pae00680
  • adenosine ribonucleotides de novo biosynthesis PWY-7219
  • superpathway of adenosine nucleotides de novo biosynthesis I PWY-7229
  • superpathway of purine nucleotides de novo biosynthesis I PWY-841
  • superpathway of adenosine nucleotides de novo biosynthesis II PWY-6126
    KEGG Reactions: Not Available
    SMPDB Reactions:
    Adenosine diphosphate+Thumb+4 Thumb+Thumb ↔ Thumb+3 Thumb+Thumb
    Adenosine diphosphate + Phosphate + 4 Hydrogen ion + ADP ↔ Water + 3 Hydrogen ion + Adenosine triphosphate
    ReactionCard
    PseudoCyc/BioCyc Reactions:
    Thumb+Thumb+H(+)(In) → Thumb+Thumb+H(+)(Out)
    Adenosine triphosphate + Water + H(+)(In) → ADP + Inorganic phosphate + H(+)(Out)
    ReactionCard
    Thumb+Thumb+H(+)(In) → Thumb+Thumb+H(+)(Out)
    Adenosine triphosphate + Water + H(+)(In) → ADP + Inorganic phosphate + H(+)(Out)
    ReactionCard
    Adenosine diphosphate+Thumb+4 Thumb+Thumb ↔ Thumb+3 Thumb+Thumb
    Adenosine diphosphate + Phosphate + 4 Hydrogen ion + ADP ↔ Water + 3 Hydrogen ion + Adenosine triphosphate
    ReactionCard
    Thumb
    ATP + H+[cytosol] + H2O ↔ ADP + phosphate + H+[periplasm]
    ReactionCard
    PAMDB001633+PAMDB110477+PAMDB000142 → PAMDB001633+PAMDB110479+PAMDB110244
    Hydrogen ion + ATP + Water → Hydrogen ion + ADP + phosphate
    ReactionCard
    Complex Reactions:
    Thumb+Thumb+H(+)(In) → Thumb+Thumb+H(+)(Out)
    Adenosine triphosphate + Water + H(+)(In) → ADP + Inorganic phosphate + H(+)(Out)
    ReactionCard
    Thumb+Thumb+H(+)(In) → Thumb+Thumb+H(+)(Out)
    Adenosine triphosphate + Water + H(+)(In) → ADP + Inorganic phosphate + H(+)(Out)
    ReactionCard
    Transports: Not Available
    Metabolites:
    PAMDB IDNameView
    PAMDB000148Adenosine triphosphateMetaboCard
    PAMDB000345ADPMetaboCard
    PAMDB001633Hydrogen ionMetaboCard
    PAMDB001776Inorganic phosphateMetaboCard
    PAMDB000383PhosphateMetaboCard
    PAMDB000142WaterMetaboCard
    GO Classification:
    Component
    macromolecular complex
    protein complex
    proton-transporting ATP synthase complex, catalytic core F(1)
    proton-transporting two-sector ATPase complex
    proton-transporting two-sector ATPase complex, catalytic domain
    Function
    adenyl nucleotide binding
    adenyl ribonucleotide binding
    ATP binding
    binding
    catalytic activity
    cation transmembrane transporter activity
    hydrogen ion transmembrane transporter activity
    hydrogen ion transporting ATP synthase activity, rotational mechanism
    hydrogen-exporting ATPase activity, phosphorylative mechanism
    hydrolase activity
    hydrolase activity, acting on acid anhydrides
    hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    inorganic cation transmembrane transporter activity
    ion transmembrane transporter activity
    monovalent inorganic cation transmembrane transporter activity
    nucleoside binding
    nucleoside-triphosphatase activity
    nucleotide binding
    proton-transporting ATPase activity, rotational mechanism
    purine nucleoside binding
    pyrophosphatase activity
    substrate-specific transmembrane transporter activity
    transmembrane transporter activity
    transporter activity
    Process
    ATP biosynthetic process
    ATP metabolic process
    ATP synthesis coupled proton transport
    cellular nitrogen compound metabolic process
    establishment of localization
    hydrogen transport
    metabolic process
    nitrogen compound metabolic process
    nucleobase, nucleoside and nucleotide metabolic process
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
    nucleoside phosphate metabolic process
    nucleotide metabolic process
    proton transport
    purine nucleoside triphosphate biosynthetic process
    purine nucleoside triphosphate metabolic process
    purine nucleotide biosynthetic process
    purine nucleotide metabolic process
    purine ribonucleoside triphosphate biosynthetic process
    purine ribonucleoside triphosphate metabolic process
    transport
    Gene Properties
    Locus tag: PA5554
    Strand: -
    Entrez Gene ID: 878083
    Accession: NP_254241.1
    GI: 15600747
    Sequence start: 6248278
    Sequence End: 6249654
    Sequence Length: 1376
    Gene Sequence: 
    >PA5554
ATGAGTAGCGGACGTATCGTTCAAATCATCGGCGCCGTGATCGACGTGGAATTCCCGCGCGATGCCGTGCCGAGCATCTATGAAGCCCTGAAGGTTCAGGGCGTTGAAACCACCCTGGAAGTCCAGCAGCAGCTGGGCGACGGCGTGGTTCGTTCCATTGCGATGGGTTCCACCGAAGGCCTCAAGCGTGGCCTGAACGTGGACAGCACTGGTGCTGCCATCTCCGTGCCGGTCGGTAAAGCGACCCTGGGCCGGATCATGGACGTACTGGGTAACCCGATCGACGAAGCCGGTCCCATCGGCGAAGAAGAGCGCTGGGGCATCCACCGCGAAGCTCCGTCCTATGCCGACCAGGCTGGCGGCAACGAGCTGCTGGAAACCGGCATCAAGGTGATCGACCTGGTCTGCCCGTTCGCCAAGGGCGGCAAGGTAGGCCTGTTCGGCGGCGCCGGCGTGGGCAAGACCGTCAACATGATGGAACTGATCCGTAACATCGCCATCGAGCACAGCGGTTATTCCGTGTTCGCGGGTGTGGGCGAGCGTACTCGTGAGGGTAACGACTTCTACCACGAGATGAAGGACTCCAACGTACTGGACAAGGTAGCCCTGGTATACGGCCAGATGAACGAGCCGCCGGGCAACCGTCTGCGCGTCGCACTGACCGGCCTGACCATGGCCGAGAAGTTCCGTGACGAAGGCCGTGACGTTCTGTTGTTCATCGACAACATCTACCGTTACACCCTCGCCGGTACCGAAGTATCCGCACTGCTGGGCCGTATGCCGTCCGCGGTGGGCTATCAGCCGACCCTGGCCGAAGAGATGGGCGTTCTGCAGGAGCGCATCACCTCCACCAAGAAAGGCTCGATCACCTCGATCCAGGCCGTATACGTTCCCGCGGACGACCTCACCGACCCGTCCCCGGCGACCACCTTCGCCCACCTGGACGCGACCGTCGTACTGTCCCGTGACATCGCCTCGCTGGGTATCTACCCCGCGGTCGACCCGCTGGACTCCACCTCTCGCCAGCTCGATCCGCTGGTGATCGGCCAGGATCACTACGACACCGCTCGCGGCGTCCAGTATGTTCTGCAGCGCTACAAGGAGCTGAAGGACATCATCGCGATCCTGGGCATGGACGAACTGTCCGAAGCCGACAAGCTGCTGGTGGCGCGCGCTCGTAAGATCCAGCGCTTCCTGTCCCAGCCGTTCTTCGTAGCGGAAGTCTTCACCGGCTCGCCGGGCAAGTACGTTTCCCTGAAGGACACCATCGCTGGCTTCAAGGGCATTCTCAACGGCGACTACGATCACCTGCCGGAGCAGGCGTTCTACATGGTCGGCGGTATCGAAGAAGCAGTCGAGAAAGCCAAAAAACTGTAA
    Protein Properties
    Protein Residues: 458
    Protein Molecular Weight: 49.5 kDa
    Protein Theoretical pI: 4.73
    Hydropathicity (GRAVY score): -0.061
    Charge at pH 7 (predicted): -14.57
    Protein Sequence: 
    >PA5554
MSSGRIVQIIGAVIDVEFPRDAVPSIYEALKVQGVETTLEVQQQLGDGVVRSIAMGSTEGLKRGLNVDSTGAAISVPVGKATLGRIMDVLGNPIDEAGPIGEEERWGIHREAPSYADQAGGNELLETGIKVIDLVCPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMKDSNVLDKVALVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKKGSITSIQAVYVPADDLTDPSPATTFAHLDATVVLSRDIASLGIYPAVDPLDSTSRQLDPLVIGQDHYDTARGVQYVLQRYKELKDIIAILGMDELSEADKLLVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIAGFKGILNGDYDHLPEQAFYMVGGIEEAVEKAKKL
    References
    External Links:
    Resource Link
    Genome ID: PA5554
    Entrez Gene ID: 878083
    NCBI Protein ID: 15600747
    General Reference: PaperBLAST - Find papers about PA5554 and its homologs