Amino-acid acetyltransferase (PA5204)

Identification
Name: Amino-acid acetyltransferase
Synonyms:
  • N-acetylglutamate synthase
  • AGS
  • NAGS
Gene Name: argA
Enzyme Class:
Biological Properties
General Function: Involved in cellular amino acid biosynthetic process
Specific Function: Acetyl-CoA + L-glutamate = CoA + N-acetyl-L- glutamate
Cellular Location: Cytoplasm (Probable)
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb ↔ Thumb+Thumb+Thumb+Thumb
Acetyl-CoA + L-Glutamate ↔ N-Acetyl-L-alanine + Coenzyme A + Hydrogen ion + N-Acetylglutamic acid
ReactionCard
Thumb+Thumb ↔ Thumb+Thumb
Acetyl-CoA + L-Glutamate ↔ Coenzyme A + N-Acetyl-L-alanine
ReactionCard
SMPDB Reactions:
Thumb+L-Glutamic acid+Thumb ↔ N-Acetyl-L-alanine+Thumb+Thumb+N-Acetylglutamic acid+Thumb+Thumb
Acetyl-CoA + L-Glutamic acid + L-Glutamate ↔ N-Acetyl-L-alanine + Coenzyme A + Hydrogen ion + N-Acetylglutamic acid + N-Acetyl-L-alanine + N-Acetylglutamic acid
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb+Thumb ↔ Thumb+Thumb+Thumb+Thumb
Acetyl-CoA + L-Glutamate ↔ N-Acetyl-L-alanine + Coenzyme A + Hydrogen ion + N-Acetylglutamic acid
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Thumb+Thumb ↔ Thumb+Thumb
Acetyl-CoA + L-Glutamate ↔ Coenzyme A + N-Acetyl-L-alanine
ReactionCard
Thumb+L-Glutamic acid+Thumb ↔ N-Acetyl-L-alanine+Thumb+Thumb+N-Acetylglutamic acid+Thumb+Thumb
Acetyl-CoA + L-Glutamic acid + L-Glutamate ↔ N-Acetyl-L-alanine + Coenzyme A + Hydrogen ion + N-Acetylglutamic acid + N-Acetyl-L-alanine + N-Acetylglutamic acid
ReactionCard
Thumb
L-glutamate + acetyl-CoA → N-acetyl-L-glutamate + coenzyme A + H+
ReactionCard
PAMDB000175+PAMDB110382 → PAMDB120267+PAMDB110248+PAMDB001633
L-Methionine + acetyl-CoA → N-α-acetyl-L-methionine + coenzyme A + Hydrogen ion
ReactionCard
Complex Reactions: Not Available
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000298Acetyl-CoAMetaboCard
PAMDB000381Coenzyme AMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000055L-GlutamateMetaboCard
PAMDB000272N-Acetyl-L-alanineMetaboCard
PAMDB001824N-Acetylglutamic acidMetaboCard
GO Classification:
Component
cell part
cytoplasm
intracellular part
Function
acetyl-CoA:L-glutamate N-acetyltransferase activity
acetyltransferase activity
acyltransferase activity
catalytic activity
N-acetyltransferase activity
transferase activity
transferase activity, transferring acyl groups
transferase activity, transferring acyl groups other than amino-acyl groups
Process
arginine biosynthetic process
arginine metabolic process
cellular amino acid and derivative metabolic process
cellular amino acid biosynthetic process
cellular amino acid metabolic process
cellular metabolic process
glutamine family amino acid metabolic process
metabolic process
Gene Properties
Locus tag: PA5204
Strand: -
Entrez Gene ID: 879475
Accession: NP_253891.1
GI: 15600397
Sequence start: 5858158
Sequence End: 5859456
Sequence Length: 1298
Gene Sequence: 
>PA5204
ATGCCCGACTACGTCAACTGGTTACGTCACGCTTCGCCCTACATCAACTCGCACCGGGACCGCACCTTCGTGGTCATGCTCCCCGGCGAAGGGGTGGAGCATCCCAATTTCGGCAATATCGTCCACGACCTAGTCCTTCTCCACAGCCTCGGTGCGCGCCTGGTGCTGGTGCACGGTTCGCGTCCGCAGATCGAGGCGCGCCTGGCCGCGCGCGGCCTGGCTCCGCGCTATCACCGCGACCTGCGAGTGACCGATGCACCGACCCTGGAGTGCGTCATCGACGCCGTGGGTAGCCTGCGCATCGCCATCGAGGCGCGGCTGTCGATGGACATGGCCGCCTCGCCGATGCAGGGCGCGCGCCTGCGGGTCGCTGGCGGCAACCTGGTCACCGCGCGGCCGATCGGCGTGGTCGAGGGTGTCGACTATCACCATACCGGTGAGGTCCGTCGCATCGACCGCAAGGGTATTGGCCGCCTTCTCGACGAGCGCAGCATCGTTCTGCTCTCGCCGCTGGGCTACTCGCCGACCGGGGAAATCTTCAACCTGGCCTGTGAAGACGTGGCCATGCGCGCCGCCATCGACCTGGAAGCGGAAAAGCTGATTCTCTACGGCGCCGAACAGGGCTTGCTGGACGCATCCGGCAAACTGGTCCGCGAACTGCGCCCGCAGCAGGTGCCCGCGCACCTGCAACGGCTGGGCAACAGCTACCAGGCCGAGCTGCTGGACGCCGCGGCGCAGGCCTGCCGGGCCGGGGTCAAGCGCAGCCATATCGTCAGCTACACCGAGGACGGCGCGCTGCTCAGCGAGCTATTCACCCGCACCGGCAACGGCACCCTGGTCGCCCAGGAGCAGTTCGAGCAGTTGCGCGAGGCGGGCATCGAGGACGTTGGCGGGCTGATCGAGCTGATCCGCCCGCTGGAAGAGCAGGGCATCCTGGTACGCCGTTCCCGCGAGGTGCTGGAACGCGAGATCGAACAGTTCAGCATCGTCGAGCGCGAAGGGCTGATCATCGCCTGCGCCGCGCTCTACCCGATCGCCGATTCCGAGGCGGGCGAGCTGGCCTGTCTGGCGGTCAACCCGGAGTACCGCCACGGCGGGCGTGGCGACGAACTGCTGGAGCGGATCGAGGAGCGCGCGCGCGGACTCGGCCTGAAGACCCTGTTCGTGCTCACCACGCGGACCGCGCACTGGTTCCGCGAGCGCGGCTTCCAGCCTAGCAGCGTCGAACGGCTACCGGCGGCGCGGGCCTCGCTGTACAACTTCCAGCGCAATTCGCAGGTATTCGAGAAGAGCCTGTGA
Protein Properties
Protein Residues: 432
Protein Molecular Weight: 47.9 kDa
Protein Theoretical pI: 6.46
Hydropathicity (GRAVY score): -0.148
Charge at pH 7 (predicted): -4
Protein Sequence: 
>PA5204
MPDYVNWLRHASPYINSHRDRTFVVMLPGEGVEHPNFGNIVHDLVLLHSLGARLVLVHGSRPQIEARLAARGLAPRYHRDLRVTDAPTLECVIDAVGSLRIAIEARLSMDMAASPMQGARLRVAGGNLVTARPIGVVEGVDYHHTGEVRRIDRKGIGRLLDERSIVLLSPLGYSPTGEIFNLACEDVAMRAAIDLEAEKLILYGAEQGLLDASGKLVRELRPQQVPAHLQRLGNSYQAELLDAAAQACRAGVKRSHIVSYTEDGALLSELFTRTGNGTLVAQEQFEQLREAGIEDVGGLIELIRPLEEQGILVRRSREVLEREIEQFSIVEREGLIIACAALYPIADSEAGELACLAVNPEYRHGGRGDELLERIEERARGLGLKTLFVLTTRTAHWFRERGFQPSSVERLPAARASLYNFQRNSQVFEKSL
References
External Links:
Resource Link
Genome ID: PA5204
Entrez Gene ID: 879475
NCBI Protein ID: 15600397
General Reference: PaperBLAST - Find papers about PA5204 and its homologs