Lipopolysaccharide heptosyltransferase 1 (PA5011)

Identification
Name: Lipopolysaccharide heptosyltransferase 1
Synonyms: Not Available
Gene Name: rfaC
Enzyme Class: Not Available
Biological Properties
General Function: Involved in transferase activity, transferring glycosyl groups
Specific Function: Heptose transfer to the lipopolysaccharide core. It transfers the innnermost heptose to [4'-P](3-deoxy-D-manno- octulosonic acid)2-IVA
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions: Not Available
SMPDB Reactions:
Thumb+Thumb → Thumb+Adenosine diphosphate+heptosyl-Kdo2-lipid A+Thumb+Thumb
(KDO)2-lipid A + ADP-L-glycero-beta-D-manno-heptose → Hydrogen ion + Adenosine diphosphate + heptosyl-Kdo2-lipid A + ADP + Heptosyl-KDO2-lipid A
ReactionCard
PseudoCyc/BioCyc Reactions:
α-Kdo-(2->4)-α-Kdo-(2->6)-lipid IVA+Thumb ? Thumb+heptosyl-Kdo2-lipid IVA+Thumb
α-Kdo-(2->4)-α-Kdo-(2->6)-lipid IVA + ADP-L-Glycero-D-manno-heptose ? Hydrogen ion + heptosyl-Kdo2-lipid IVA + ADP
ReactionCard
Thumb+Thumb+Thumb → Thumb+Thumb
Hydrogen ion + KDO2-Lipid A + ADP-L-Glycero-D-manno-heptose → Heptosyl-KDO2-lipid A + ADP
ReactionCard
Complex Reactions:
Thumb+Thumb → Thumb+Thumb+heptosyl-kdo2-lipidA
ADP-L-Glycero-D-manno-heptose + KDO2-Lipid A → ADP + Hydrogen ion + heptosyl-kdo2-lipidA
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB006296(KDO)2-lipid AMetaboCard
PAMDB000345ADPMetaboCard
PAMDB006297ADP-L-glycero-beta-D-manno-heptoseMetaboCard
PAMDB000961ADP-L-Glycero-D-manno-heptoseMetaboCard
PAMDB001334Heptosyl-KDO2-lipid AMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB001447KDO2-Lipid AMetaboCard
GO Classification:
Function
catalytic activity
transferase activity
transferase activity, transferring glycosyl groups
Process
lipid biosynthetic process
lipid metabolic process
lipopolysaccharide biosynthetic process
metabolic process
primary metabolic process
Gene Properties
Locus tag: PA5011
Strand: -
Entrez Gene ID: 881533
Accession: NP_253698.1
GI: 15600204
Sequence start: 5629786
Sequence End: 5630853
Sequence Length: 1067
Gene Sequence: 
>PA5011
ATGAGGGTGCTGCTGGTCAAGACCTCGTCCCTCGGCGACGTGATCCACACCCTGCCGGCGCTTACCGACGCCGCCCGGGCGATTCCCGGCATCCAGTTCGACTGGGTGGTGGAGGAAGGTTTCGCCGAGATTCCCGCCTGGCATCCGGCGGTGGCGCGGGTGATCCCGGTGGCGATCCGGCGCTGGCGCAAGAACCTCTGGCAGACCCTGCGCAACGGCGAATGGCGGCGCTTCAAGCAGCGCCTGAAGGAAGTCGACTATGACCTGGTGATCGACGCCCAGGGGCTGCTGAAGAGTGCCTGGCTGACCCGCTACGTGGGCAAGACGCCGGTCGCCGGTCTCGATCGCGACTCGGCGCGCGAGCCGCTCGCCAGCCGCTTCTATCGCCGTGCCTATCCGGTCGCCTGGGGACAGCATGCGGTGGAGCGCACGCGCCAGTTGTTCGCCCAGGCGCTGGACTACCCGTTGCCCGAGTCGGTCGGTGACTATGGCCTGGACCGCGAGCAGTTGGCCGACGCCGACCCTGGCGCGCCGTACCTGGTGTTCCTGCACGGTACTACCTGGGTCACCAAGCATTGGCCGGAAGCCTACTGGCGCGAACTGGCCGAGCGCATGTGCGAGCGCGGCTGGTCGGTGCGCCTGCCCTGGGGCAGCGCCGCCGAGCGGGAGCGGGCCGGGCGCCTGGCGGCGGGGTTGGAAAATGCCGCGGTACTCCCCAGATTATCCCTGGCCGGCATGGCCAAGGTGCTTGCCGGCGCGCGCGCCTGCGTGGCGGTGGATACCGGCCTCGGTCACCTGGCGGCGGCGCTGGACGTGCCGACGCTGTCGCTGTTCGGCCCGACCAATCCTGGCTTCACCGGCGCCTACGGGCGTTCCCAGGTCCACCTGGGCAGCGACTTCCCCTGTGCGCCGTGCCTGAAGAAGACTTGTACCTACCAGCCGACCGAAGAGGATCGCAAACTGTTCGATCTCAAGCGTGAGCAGCCGCTGTGCTTCACCCGGCTGAATCCCCAGCGCGTGGCCACCCAGCTGGAGGCCATGCTGCTGGCCCCGGAGACCCTCCGATGA
Protein Properties
Protein Residues: 355
Protein Molecular Weight: 39.7 kDa
Protein Theoretical pI: 9.16
Hydropathicity (GRAVY score): -0.224
Charge at pH 7 (predicted): 8.5
Protein Sequence: 
>PA5011
MRVLLVKTSSLGDVIHTLPALTDAARAIPGIQFDWVVEEGFAEIPAWHPAVARVIPVAIRRWRKNLWQTLRNGEWRRFKQRLKEVDYDLVIDAQGLLKSAWLTRYVGKTPVAGLDRDSAREPLASRFYRRAYPVAWGQHAVERTRQLFAQALDYPLPESVGDYGLDREQLADADPGAPYLVFLHGTTWVTKHWPEAYWRELAERMCERGWSVRLPWGSAAERERAGRLAAGLENAAVLPRLSLAGMAKVLAGARACVAVDTGLGHLAAALDVPTLSLFGPTNPGFTGAYGRSQVHLGSDFPCAPCLKKTCTYQPTEEDRKLFDLKREQPLCFTRLNPQRVATQLEAMLLAPETLR
References
External Links:
Resource Link
Genome ID: PA5011
Entrez Gene ID: 881533
NCBI Protein ID: 15600204
General Reference: PaperBLAST - Find papers about PA5011 and its homologs