Identification
Name: L-lactate permease
Synonyms: Not Available
Gene Name: lldP
Enzyme Class: Not Available
Biological Properties
General Function: Involved in lactate transmembrane transporter activity
Specific Function: Transports L-lactate across the membrane. Can also transport D-lactate and glycolate. Seems to be driven by a proton motive force
Cellular Location: Cell inner membrane; Multi-pass membrane protein
KEGG Pathways:
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Thumb
    (S)-lactate[periplasm] + H+[periplasm] → (S)-lactate[cytosol] + H+[cytosol]
    ReactionCard
    Complex Reactions: Not Available
    Transports:
    Metabolites:
    PAMDB IDNameView
    PAMDB000334D-Lactic acidMetaboCard
    PAMDB000475Glycolic acidMetaboCard
    PAMDB001633Hydrogen ionMetaboCard
    PAMDB000079L-Lactic acidMetaboCard
    GO Classification:
    Function
    carboxylic acid transmembrane transporter activity
    lactate transmembrane transporter activity
    monocarboxylic acid transmembrane transporter activity
    organic acid transmembrane transporter activity
    substrate-specific transmembrane transporter activity
    transmembrane transporter activity
    transporter activity
    Process
    anion transport
    establishment of localization
    ion transport
    lactate transport
    organic anion transport
    transport
    Gene Properties
    Locus tag: PA4770
    Strand: +
    Entrez Gene ID: 881808
    Accession: NP_253458.1
    GI: 15599964
    Sequence start: 5355387
    Sequence End: 5357075
    Sequence Length: 1688
    Gene Sequence:
    >PA4770
    ATGCAAGCCTGGCAACAACTCTATACCCCCCTGGGCAGTCTCGGCCTGTCGGCCGCCGCGGCCGTCATCCCGATCGTGTTCTTCTTCCTCGCCCTGGCGGTATTCCGCCTCAAGGGCCACATCGCCGGCAGCATCACCCTGGCGCTGGCCATCGCGGTGGCCATCTTCGCCTTCCACATGCCCGCCGACATGGCCTTCGCCGCCGCCGGCTACGGCTTCCTCTACGGTCTCTGGCCGATCGCCTGGATCATCGTCGCCGCGGTCTTCCTCTACAAACTGACGGTGAAGAGCGGCCAGTTCGAGGTGATCCGCAGCTCGGTGCTGTCGATTACCGGCGACCAGCGCCTGCAGGTACTGCTGATCGGCTTCTCCTTCGGGGCCTTCCTCGAAGGCGCCGCCGGTTTCGGCGCGCCGGTGGCGATCACCGCCGCCCTGCTCGTCGGCCTCGGCTTCAATCCGCTCTACGCCGCCGGCCTGTGCCTGATCGCCAACACTGCGCCGGTGGCCTTTGGCGCACTGGGCATCCCGATCATCGTCGCCGGCCAGGTGACCGGCATCGACGCCTTCAAGATCGGCGCCATGACCGGCCGCCAACTGCCGTTCCTGTCGATCCTGGTACCGTTCTGGCTGGTGTTCATGATGGACGGCTGGCGCGGCATCCGCGAAACCTGGCCGGCCGCCATCGTCGCCGGCGGCAGCTTCGCCATCACCCAGTACCTGACGTCCAACTTCATCGGCCCGGAGTTGCCGGACATCACCTCGGCACTGGTCAGCCTGGTCTCCCTGACCCTGTTCCTCAAGGTCTGGCAGCCGCAGGGCGCCAGCGAAGCGCTCGCCGCAGGCGGAGGCGCGGCCGTGGCCGTGGCTGGTGGCGGCTTCGGCGGGCAACGCAGCGTCGAACCGTCCGCCTACAGCTTCGGCGAGATCCTCAAGGCCTGGTCGCCGTTCCTGGTGCTCACCGTACTGGTGACCATCTGGACCCTGAAACCTTTCAAGGCCCTGTTCGCCCCGGGCGGCGAGCTCTACTGGCTGGTGTTCAACTTCGCCATCCCGCACCTCGACCAACTGGTGGTCAAGGGCGCGCCGATCGCCACCAGCGCCACGCCGATCGCGGCGGTATTCAAGTTCGACCCGATCTCCGCCACCGGCACGGCGATCTTCCTCTCGGCGTTGGTATCGATGTTCATTCTGCGCATCGGAGCGAAGATTGGTATTACCACTTTCAAGGAAGTCCTGGTAGAGCTGAAGTGGCCGATCCTGTCCATCGGCATGGTCCTGGCCTTCGCCTTCGTCACCAACTACTCGGGCATGTCCACCACCCTGGCCCTGGTCCTGGCCGGTACCGGCGCGGCGTTCCCGTTCTTCTCGCCGTTCCTCGGCTGGCTGGGGGTATTCCTGACCGGTTCGGATACGTCCTCCAACGCCCTGTTCAGCTCCCTGCAGTCGACCACCGCGCACCAGATCGGGGTCAGCGACACCCTGCTGGTGGCCGCCAATACCAGCGGCGGCGTGACCGGCAAGATGATCTCCCCGCAATCTATCGCCGTGGCCTGCGCCGCGACCGGGATGGTCGGCAAGGAATCCGACCTGTTCCGCTTCACCCTGAAGCACAGCCTGATCTTCGCCGCGCTGGTCGGACTGATCACCCTGGCCCAGGCATACCTATTCACCGGCATGCTGGTGCACTGA
    Protein Properties
    Protein Residues: 562
    Protein Molecular Weight: 58.7 kDa
    Protein Theoretical pI: 9.21
    Hydropathicity (GRAVY score): 0.956
    Charge at pH 7 (predicted): 5.37
    Protein Sequence:
    >PA4770
    MQAWQQLYTPLGSLGLSAAAAVIPIVFFFLALAVFRLKGHIAGSITLALAIAVAIFAFHMPADMAFAAAGYGFLYGLWPIAWIIVAAVFLYKLTVKSGQFEVIRSSVLSITGDQRLQVLLIGFSFGAFLEGAAGFGAPVAITAALLVGLGFNPLYAAGLCLIANTAPVAFGALGIPIIVAGQVTGIDAFKIGAMTGRQLPFLSILVPFWLVFMMDGWRGIRETWPAAIVAGGSFAITQYLTSNFIGPELPDITSALVSLVSLTLFLKVWQPQGASEALAAGGGAAVAVAGGGFGGQRSVEPSAYSFGEILKAWSPFLVLTVLVTIWTLKPFKALFAPGGELYWLVFNFAIPHLDQLVVKGAPIATSATPIAAVFKFDPISATGTAIFLSALVSMFILRIGAKIGITTFKEVLVELKWPILSIGMVLAFAFVTNYSGMSTTLALVLAGTGAAFPFFSPFLGWLGVFLTGSDTSSNALFSSLQSTTAHQIGVSDTLLVAANTSGGVTGKMISPQSIAVACAATGMVGKESDLFRFTLKHSLIFAALVGLITLAQAYLFTGMLVH
    References
    External Links:
    Resource Link
    Genome ID: PA4770
    Entrez Gene ID: 881808
    NCBI Protein ID: 15599964
    General Reference: PaperBLAST - Find papers about PA4770 and its homologs