Mannose-1-phosphate guanylyltransferase (PA3551)

Identification
Name: Mannose-1-phosphate guanylyltransferase
Synonyms:
  • GDP-mannose pyrophosphorylase
  • GMP
  • GMPP
Gene Name: manC
Enzyme Class:
Biological Properties
General Function: Involved in nucleotidyltransferase activity
Specific Function: Involved in the biosynthesis of the capsular polysaccharide colanic acid
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb ↔ Thumb+Thumb
Guanosine triphosphate + D-Mannose 1-phosphate ↔ Pyrophosphate + Guanosine diphosphate mannose
ReactionCard
SMPDB Reactions:
Thumb+Thumb+Thumb → Pyrophosphate+Thumb
D-Mannose 1-phosphate + Guanosine triphosphate + Hydrogen ion → Pyrophosphate + Guanosine diphosphate mannose
ReactionCard
α-D-mannose 1-phosphate+Thumb+Thumb → Thumb+Pyrophosphate
α-D-mannose 1-phosphate + Guanosine triphosphate + Hydrogen ion → Guanosine diphosphate mannose + Pyrophosphate
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb+Thumb ↔ Thumb+Thumb
Guanosine triphosphate + D-Mannose 1-phosphate ↔ Pyrophosphate + Guanosine diphosphate mannose
ReactionCard
Thumb+Thumb+Thumb → Thumb+Thumb
Hydrogen ion + D-Mannose 1-phosphate + Guanosine triphosphate → Guanosine diphosphate mannose + Pyrophosphate
ReactionCard
Complex Reactions:
Thumb+Thumb+Thumb → Thumb+Thumb
Guanosine diphosphate + Hydrogen ion + D-Mannose 1-phosphate → Guanosine diphosphate mannose + Phosphate
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000386D-Mannose 1-phosphateMetaboCard
PAMDB000296Guanosine diphosphateMetaboCard
PAMDB000279Guanosine diphosphate mannoseMetaboCard
PAMDB000319Guanosine triphosphateMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000383PhosphateMetaboCard
PAMDB000633PyrophosphateMetaboCard
GO Classification:
Function
catalytic activity
nucleotidyltransferase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
Process
biosynthetic process
carbohydrate metabolic process
lipid biosynthetic process
lipid metabolic process
lipopolysaccharide biosynthetic process
metabolic process
polysaccharide metabolic process
primary metabolic process
Gene Properties
Locus tag: PA3551
Strand: +
Entrez Gene ID: 879142
Accession: NP_252241.1
GI: 15598747
Sequence start: 3978031
Sequence End: 3979476
Sequence Length: 1445
Gene Sequence: 
>PA3551
ATGATCCCAGTAATCCTTTCCGGTGGCAGCGGCTCGCGACTCTGGCCTCTTTCCCGCAAGCAGTACCCCAAGCAGTTCCTCGCCCTCACCGGCGACGACACCCTGTTCCAGCAGACCATCAAGCGCCTGGCCTTCGACGGCATGCAGGCACCGCTGCTGGTGTGCAACAAGGAGCACCGCTTCATCGTCCAGGAACAGCTGGAGGCACAGAACCTGGCGAGCCAGGCGATCCTCCTCGAACCCTTCGGCCGCAACACGGCGCCGGCGGTGGCCATCGCCGCGATGAAACTGGTCGCCGAAGGCCGCGACGAACTGCTGCTGATCCTTCCCGCCGACCACGTGATCGAGGACCAGCGCGCCTTCCAGCAGGCCCTGGCGCTGGCCACCAACGCCGCCGAAAAGGGCGAGATGGTGCTCTTCGGCATTCCCGCCAGCCGCCCCGAGACCGGCTACGGCTACATCCGCGCGAGCGCCGATGCGCAACTGCCGGAAGGCGTCAGCCGGGTGCAGAGCTTCGTCGAGAAGCCCGACGAAGCCCGCGCCCGCGAGTTCGTCGCCGCCGGCGGCTACTACTGGAACAGCGGCATGTTCCTGTTCCGCGCCAGCCGCTACCTGGAAGAACTGAAGAAGCACGACGCCGACATCTACGACACCTGCCTGCTGGCCCTGGAGCGCAGCCAGCACGACGGCGACCTGGTGAACATCGACGCCGCCACCTTCGAATGCTGCCCGGACAACTCCATCGACTACGCGGTGATGGAGAAGACCTCACGCGCCTGCGTGGTGCCGCTGTCCGCCGGCTGGAACGATGTCGGCAGCTGGTCGTCGATCTGGGACGTGCACGCCAAGGACGCCAACGGCAACGTCACCAAGGGCGACGTGCTGGTCCACGACAGCCACAACTGCCTGGTGCACGGCAACGGCAAGCTGGTCTCGGTGATCGGCCTGGAGGACATCGTGGTGGTGGAAACCAAGGACGCCATGATGATCGCCCACAAGGACCGGGTGCAGGACGTCAAGCACGTGGTCAAGGACCTCGACGCCCAGGGCCGCAGCGAGACCCAGAACCACTGCGAGGTCTACCGCCCGTGGGGCTCCTACGACTCGGTGGACATGGGCGGCCGCTTCCAGGTCAAGCACATCACCGTGAAGCCCGGCGCGCGCCTCTCGCTGCAGATGCACCACCACCGCGCCGAGCACTGGATCGTGGTTTCCGGGACCGCCCAGGTGACCTGCGACGACAAGACCTTCCTGCTCACCGAGAACCAGTCGACCTACATCCCGATCGCCTCCGTGCACCGCCTGGCCAACCCCGGCAAGATCCCGCTGGAGATCATCGAGGTGCAGTCCGGCAGCTACCTCGGCGAGGACGACATCGAGCGCCTGGAAGACGTCTACGGGCGCACCGCAGAACCGGCCCTGCAAGTGGTCGCCGGCAGCCGCTGA
Protein Properties
Protein Residues: 481
Protein Molecular Weight: 53.1 kDa
Protein Theoretical pI: 5.43
Hydropathicity (GRAVY score): -0.21
Charge at pH 7 (predicted): -14.13
Protein Sequence: 
>PA3551
MIPVILSGGSGSRLWPLSRKQYPKQFLALTGDDTLFQQTIKRLAFDGMQAPLLVCNKEHRFIVQEQLEAQNLASQAILLEPFGRNTAPAVAIAAMKLVAEGRDELLLILPADHVIEDQRAFQQALALATNAAEKGEMVLFGIPASRPETGYGYIRASADAQLPEGVSRVQSFVEKPDEARAREFVAAGGYYWNSGMFLFRASRYLEELKKHDADIYDTCLLALERSQHDGDLVNIDAATFECCPDNSIDYAVMEKTSRACVVPLSAGWNDVGSWSSIWDVHAKDANGNVTKGDVLVHDSHNCLVHGNGKLVSVIGLEDIVVVETKDAMMIAHKDRVQDVKHVVKDLDAQGRSETQNHCEVYRPWGSYDSVDMGGRFQVKHITVKPGARLSLQMHHHRAEHWIVVSGTAQVTCDDKTFLLTENQSTYIPIASVHRLANPGKIPLEIIEVQSGSYLGEDDIERLEDVYGRTAEPALQVVAGSR
References
External Links:
Resource Link
Genome ID: PA3551
Entrez Gene ID: 879142
NCBI Protein ID: 15598747
General Reference: PaperBLAST - Find papers about PA3551 and its homologs