Aspartate-semialdehyde dehydrogenase (PA3117)

Identification
Name: Aspartate-semialdehyde dehydrogenase
Synonyms:
  • ASA dehydrogenase
  • ASADH
Gene Name: asd
Enzyme Class:
Biological Properties
General Function: Involved in aspartate-semialdehyde dehydrogenase activity
Specific Function: L-aspartate 4-semialdehyde + phosphate + NADP(+) = L-4-aspartyl phosphate + NADPH
Cellular Location: Not Available
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb+Thumb ↔ Thumb+Thumb+Thumb
L-Aspartate-semialdehyde + NADP + Phosphate ↔ L-Aspartyl-4-phosphate + Hydrogen ion + NADPH
ReactionCard
Thumb+Thumb+Thumb ↔ Thumb+Thumb+Thumb
L-Aspartate-semialdehyde + Phosphate + NADP ↔ L-Aspartyl-4-phosphate + NADPH + Hydrogen ion
ReactionCard
SMPDB Reactions:
Thumb+NADPH+Thumb+Thumb → Thumb+Thumb+Thumb
L-Aspartyl-4-phosphate + NADPH + Hydrogen ion + NADPH → Phosphate + NADP + L-Aspartate-semialdehyde
ReactionCard
Thumb+NADPH+Thumb+Thumb → Thumb+Thumb+Thumb
L-Aspartyl-4-phosphate + NADPH + Hydrogen ion + NADPH → Phosphate + NADP + L-Aspartate-semialdehyde
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb+Thumb+Thumb ↔ Thumb+Thumb+Thumb
L-Aspartate-semialdehyde + NADP + Phosphate ↔ L-Aspartyl-4-phosphate + Hydrogen ion + NADPH
ReactionCard
Complex Reactions: Not Available
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB001633Hydrogen ionMetaboCard
PAMDB001776Inorganic phosphateMetaboCard
PAMDB000833L-Aspartate-semialdehydeMetaboCard
PAMDB000834L-Aspartyl-4-phosphateMetaboCard
PAMDB000089NADPMetaboCard
PAMDB000615NADPHMetaboCard
PAMDB000383PhosphateMetaboCard
GO Classification:
Component
cell part
cytoplasm
intracellular part
Function
aspartate-semialdehyde dehydrogenase activity
binding
catalytic activity
NAD or NADH binding
NADP or NADPH binding
nucleotide binding
oxidoreductase activity
oxidoreductase activity, acting on the aldehyde or oxo group of donors
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
protein binding
protein dimerization activity
Process
aspartate family amino acid metabolic process
cellular amino acid and derivative metabolic process
cellular amino acid biosynthetic process
cellular amino acid metabolic process
cellular metabolic process
lysine biosynthetic process
lysine biosynthetic process via diaminopimelate
lysine metabolic process
metabolic process
oxidation reduction
Gene Properties
Locus tag: PA3117
Strand: -
Entrez Gene ID: 882803
Accession: NP_251807.1
GI: 15598313
Sequence start: 3499486
Sequence End: 3500598
Sequence Length: 1112
Gene Sequence: 
>PA3117
ATGAAGCGTGTAGGTCTGATCGGTTGGCGCGGGATGGTGGGTTCCGTACTCATGCAGCGAATGCTGGAAGAGCGGGACTTCGACCTGATCGAGCCGGTGTTCTTCACCACGTCGAACGTCGGTGGCCAGGGCCCGGAAGTGGGCAAGGACATCGCTCCGCTGAAGGACGCCTACAGCATCGACGAGCTGAAGACCCTCGACGTGATCCTGACCTGCCAGGGCGGCGACTACACCAGCGAAGTATTCCCCAAGCTGCGCGAGGCCGGCTGGCAGGGCTACTGGATCGATGCCGCCTCCAGTCTGCGCATGGAAGACGACGCGGTGATCGTCCTCGACCCGGTCAACCGCAAGGTCATCGACCAGGCTCTGGACGCCGGCACCCGCAACTACATCGGCGGCAACTGCACCGTCAGCCTGATGCTGATGGCCCTGGGCGGGCTGTTCGACGCCGGTCTGGTCGAGTGGATGAGTGCCATGACCTACCAGGCCGCCTCCGGCGCCGGCGCGCAGAACATGCGTGAACTGCTCAAGCAGATGGGCGCCGCCCATGCATCGGTGGCGGATGACCTGGCCAACCCGGCCAGCGCGATCCTCGACATCGACCGCAAGGTGGCGGAGACCCTGCGCAGCGAAGCCTTCCCCACCGAGCATTTCGGCGCGCCGCTGGGCGGCAGCCTGATCCCCTGGATCGACAAGGAACTGCCCAACGGGCAGAGCCGCGAAGAGTGGAAGGCCCAGGCGGAGACCAACAAGATCCTTGCCCGCTTCAAGAACCCGATCCCGGTCGACGGTATCTGCGTGCGCGTCGGCGCCATGCGTTGCCACAGCCAGGCGCTGACCATCAAGTTGAACAAGGATGTGCCGCTGACCGACATCGAGGGCCTGATCAGCCAGCACAATCCCTGGGTCAAGCTGGTGCCGAACCACCGCGAGGTAAGCGTGCGCGAGCTGACCCCGGCCGCCGTCACCGGCACCCTGAGCGTTCCGGTCGGGCGCCTGCGCAAGTTGAACATGGGCTCCCAGTATCTCGGCGCCTTCACCGTCGGCGACCAGTTGCTGTGGGGCGCTGCCGAGCCGCTGCGGCGCATGTTGCGCATCCTGCTGGAGCGCTGA
Protein Properties
Protein Residues: 370
Protein Molecular Weight: 40.5 kDa
Protein Theoretical pI: 5.49
Hydropathicity (GRAVY score): -0.071
Charge at pH 7 (predicted): -4.91
Protein Sequence: 
>PA3117
MKRVGLIGWRGMVGSVLMQRMLEERDFDLIEPVFFTTSNVGGQGPEVGKDIAPLKDAYSIDELKTLDVILTCQGGDYTSEVFPKLREAGWQGYWIDAASSLRMEDDAVIVLDPVNRKVIDQALDAGTRNYIGGNCTVSLMLMALGGLFDAGLVEWMSAMTYQAASGAGAQNMRELLKQMGAAHASVADDLANPASAILDIDRKVAETLRSEAFPTEHFGAPLGGSLIPWIDKELPNGQSREEWKAQAETNKILARFKNPIPVDGICVRVGAMRCHSQALTIKLNKDVPLTDIEGLISQHNPWVKLVPNHREVSVRELTPAAVTGTLSVPVGRLRKLNMGSQYLGAFTVGDQLLWGAAEPLRRMLRILLER
References
External Links:
Resource Link
Genome ID: PA3117
Entrez Gene ID: 882803
NCBI Protein ID: 15598313
General Reference: PaperBLAST - Find papers about PA3117 and its homologs