P. aeruginosa Metabolome Database Protein PA3068

Identification

Name:

NAD-dependent glutamate dehydrogenase

Synonyms:

Not Available

Gene Name:

gdhB

Enzyme Class:

Not Available

Biological Properties

General Function:

cellular amino acid metabolic process, oxidation-reduction process, glutamate catabolic process to 2-oxoglutarate

Specific Function:

glutamate dehydrogenase (NAD+) activity

Cellular Location:

Cytoplasmic

KEGG Pathways:

glutamate degradation I GLUTAMATE-DEG1-PWY
alanine degradation II (to D-lactate) ALACAT2-PWY

KEGG Reactions:

Not Available

SMPDB Reactions:

Not Available

PseudoCyc/BioCyc Reactions:

→

L-glutamate + Water + NAD⁺ → alpha-Ketoglutarate + Ammonium + NADH + Hydrogen ion
ReactionCard

Complex Reactions:

Not Available

Transports:

Not Available

Metabolites:

Not Available

GO Classification:

Function
glutamate dehydrogenase (NAD+) activity
Process
cellular amino acid metabolic process
oxidation-reduction process
glutamate catabolic process to 2-oxoglutarate

Gene Properties

Locus tag:

PA3068

Strand:

Entrez Gene ID:

878664

Accession:

NP_251758.1

GI:

15598264

Sequence start:

3436578

Sequence End:

3441440

Sequence Length:

4862

Gene Sequence:

>PA3068
ATGGCGTTCTTCACCGCGGCCAGCAAAGCCGATTTCCAGCATCAACTGCAGACGGCACTGGCGCAGCACCTCGGCGACAAGGCGTTACCACAAGTCACGCTGTTCGCCGAACAGTTCTTCAGCCTGATCTCCCTCGATGAACTGACCCAGCGTCGGCTTTCCGACCTGGTCGGTTGCACCCTTTCCGCCTGGCGCCTGCTGGAGCGCTTCGACCGCGACCAGCCCGAAGTCCGCGTATACAACCCCGACTACGAGAAGCACGGCTGGCAATCCACCCACACCGCGGTAGAAGTGCTGCACCCGGACCTGCCGTTCCTGGTCGACTCGGTGCGCATGGAACTGAACCGTCGCGGCTACAGCATCCATACCCTGCAGACCAACGTCCTCAGCGTGCGCCGCTCGGCCAAGGGCGAGCTGAAGGAAATCCTGCCCAAGGGTAGCCAGGGCAAGGACGTCAGCCAGGAATCGCTGATGTACCTGGAGATCGACCGTTGCGCCCACGCCGGCGAACTGCGGGCGCTGGAGAAGGCCATCCTGGAAGTGCTCGGTGAAGTACGCGTGACCGTCGCCGACTTCGAACCGATGAAGGCCAAGGCCCGCGAACTGCTGACCTGGCTTGGCAAGGCCAAGCTGAAGGTGCCGGCGGAGGAACTGAAGGAAGTACGCAGCTATCTCGAATGGCTGCTGGACAACCACTTCACCTTCCTCGGCTACGAGGAATTCAGCGTCGCCGACGAGGCCGACGGCGGGCGCATGGTCTACGACGAGAAATCCTTCCTCGGCCTGACCCGTCTGCTGCGTGCCGGCCTGAGCAAGGATGACCTGCACATCGAGGACTATGCCGTCGCCTACCTGCGCGAACCGGTCCTGCTGTCCTTCGCCAAGGCTGCCCATCCGAGCCGTGTGCACCGCCCGGCCTACCCGGACTACGTGTCGATCCGCGAGCTGGACGGCAAGGGCCGGGTGATCCGCGAGTGCCGCTTCATGGGCCTGTTCACCTCCTCGGTGTACAACGAGAGCGTCAACGACATCCCCTTCATCCGCGGCAAGGTCGCCGAAGTGATGCGGCGCTCCGGTTTCGACACCAAGGCCCACCTCGGCAAGGAACTGGCCCAGGTGCTGGAAGTACTGCCGCGCGACGACCTGTTCCAGACCCCGGTGGACGAGCTGTTCAGCACCGCCCTGGCGATCGTCCGCATCCAGGAGCGCAACAAGATCCGCGTGTTCCTGCGCAAGGACCCCTACGGTCGCTTCTGCTACTGCCTGGCCTACGTGCCGCGCGACGTGTATTCCACCGAGACGCGCCTGAAGATCCAGCAGGTCCTGATGGAGCGCCTGCAGGCGAGCGACTGCGAGTTCTGGACCTTCTTCTCCGAGTCGGTGCTGGCCCGCGTGCAGTTCATCCTCCGCGTCGACCCGAAGTCGCGCATCGACATCGACCCGGCGCGCCTGGAGGAAGAAGTGATCCAGGCCTGCCGTTCCTGGCAGGACGACTACAGCAGCCTGGTGGTGGAAAACCTCGGCGAGGCCAAGGGCACCAACGTCCTGGCCGACTTCCCGAAAGGCTTCCCGGCCGGCTACCGCGAGCGCTTCGCCCCGCACTTCGCGGTGGTCGACCTGCAGCACCTGCTCAGCCTCTCCGAGCAGCGCCCGCTGGTGATGAGCTTCTACCAGCCGCTGGCGCAGGGCGAGCAGCAACTGCACTGCAAGCTGTACCACGCCGACACCCCGCTGGCCCTGTCCGACGTCCTGCCGATCCTGGAGAACCTCGGCCTGCGCGTGCTCGGCGAATTCCCCTACCGCCTGCGCCACCAGAACGGCCGCGAATACTGGATCCACGACTTCGCCTTCACCTACGCCGAAGGGCTGGACGTGGACATCCAGCAGCTCAACGAGATCCTCCAGGACGCCTTCGTCCACATCGTCAGCGGCGACGCCGAGAACGACGCCTTCAACCGCCTGGTGCTGACCGCCAACCTGCCGTGGCGCGACGTCGCCCTGCTGCGTGCCTACGCGCGTTACCTGAAGCAGATCCGCCTGGGCTTCGACCTCGGCTACATCGCCAGTGCGCTGAATGCCCACACCGACATCGCCCGCGAGCTGGTGCGGCTGTTCAAGACCCGCTTCTACCTGGCGCGCAAACTCACCGCGGAAGACCTGGAAGACAAGCAACAGAAGCTGGAGCAGGCGATCCTCGGTGCCCTCGACGAAGTCCAGGTGCTCAACGAGGACCGCATCCTGCGGCGCTACCTCGACCTGATCAAGGCGACCCTGCGGACCAACTTCTACCAGCCCGACGGCAACGGCCAGAACAAGAGCTACTTCAGCTTCAAGTTCAACCCGAAGGCCATTCCGGAGCTGCCCAGGCCGGTGCCCAAGTACGAGATCTTCGTCTACTCGCCGCGCGTCGAGGGCGTGCACCTGCGCGGCGGCAAGGTGGCTCGCGGCGGCTTGCGCTGGTCGGACCGCGAGGAAGACTTCCGCACCGAGGTGCTCGGCCTGGTCAAGGCCCAGCAGGTGAAGAACGCGGTGATCGTGCCGGTCGGCGCCAAGGGCGGCTTCGTCCCGCGCCGCCTGCCGCTTGGCGGTAGCCGCGACGAGATCCAGGCCGAGGCGATCGCCTGCTACCGGATCTTCATTTCCGGCCTGCTCGATATCACCGACAACCTCAAGGAAGGCGAAGTGGTGCCGCCGGCCAACGTGGTCCGCCACGACGAGGACGATCCCTACCTGGTGGTCGCCGCGGACAAGGGCACGGCGACCTTCTCCGACATCGCCAACGGCATCGCCGCCGAGTACGGCTTCTGGCTCGGCGACGCCTTCGCCTCGGGCGGCTCCGCCGGCTACGACCACAAGGGCATGGGGATTACCGCCAAGGGCGCCTGGGTCAGCGTGCAACGGCACTTCCGCGAACGCGGCATCGACGTGCAGAAGGACAACATCAGCGTCATCGGCATCGGCGACATGGCCGGCGACGTGTTCGGCAACGGCCTGCTGATGTCGGACAAGCTGCAACTGGTGGCCGCCTTCAACCACATGCATATCTTCATCGACCCGAACCCGGACGCCGCCAGCAGCTTCGTCGAGCGCCAGCGCCTGTTCAACCTGCCGCGTTCGAGCTGGGCCGACTACGACGCCAAGCTGATCTCCGCCGGCGGCGGGATCTTCCTGCGCAGCGCCAAGAGCATCGCCATCACCCCGGAAATGAAGGCGCGCTTCGACATCCAGGCCGACAGGCTGGCGCCCACCGAGCTGATCCATGCGCTGCTCAAGGCGCCGGTCGACCTGCTCTGGAACGGCGGGATCGGTACCTACGTGAAGTCGAGCAAGGAAACCCACGCCGATGTCGGCGACAAGGCCAACGATGGTCTGCGCGTCGACGGCCGCGAGTTGCGCGCGAAGGTGGTGGGCGAGGGCGGCAACCTGGGCATGACCCAACTGGCGCGGGTCGAGTTCGGCCTGCACGGCGGTGCCAACAACACCGACTTCATCGACAACGCCGGTGGCGTGGACTGCTCCGACCATGAGGTCAACATCAAGATCCTGCTCAACGAAGTGGTGCAGGCCGGCGACATGACCGAGAAGCAGCGCAACGCGCTGCTGGTGAAGATGACCGACGCGGTCGGCGCCCTGGTGCTGGGCAACAACTACAAGCAGACCCAGGCGCTGTCCCTGGCGCAACGTCGCGCCCGCGAGCGGATCGCCGAGTACAAGCGGCTGATGGGCGACCTCGAGGCGCGTGGCAAGCTCGATCGCGCCCTGGAGTTCCTGCCTTCCGACGAGGAGCTGGCGGAACGCATCAGTGCCGGCCAGGGGCTGACCCGCGCCGAGCTGTCGGTGCTGATCTCCTACAGCAAGATCGACCTCAAGGAATCGCTGCTGAAATCGCTGGTGCCCGACGATGACTACCTGACCCGCGACATGGAGACCGCCTTCCCGGCATTGCTGGCGGAGAAGTTCGGCGACGCCATGCGCCGCCATCGCCTGAAGCGCGAGATCGTCAGCACGCAGATCGCCAACGACCTGGTCAACCACATGGGCATCACCTTCGTGCAGCGCCTGAAGGAGTCCACCGGCATGAGCGCGGCCAACGTCGCCGGGGCCTACGTGATCGTCCGCGACGTATTCCACCTGCCGCATTGGTTCCGCCAGATCGAGAATCTCGACTACCAGGTGCCCGCTGATATCCAGCTGACCCTGATGGACGAACTGATGCGCCTCGGCCGCCGCGCCACCCGCTGGTTCCTCCGCAGCCGCCGCAACGAGCTGGACGCGGCGCGCGACGTGGCCCACTTCGGCCCGCGCATCGCCGCCCTCGGCCTGAAGCTCAACGAGCTGCTCGAAGGGCCGACCCGCGAGCTGTGGCAGGCGCGCTACCAGACCTACGTCGACGCCGGCGTGCCGGAACTGCTGGCACGCATGGTGGCCGGTACCAGCCACTTGTACACGCTGCTGCCGATCATCGAGGCGTCCGACGTGACCGGCCAGGACACCGCGGAAGTGGCCAAGGCCTATTTCGCCGTGGGCAGCGCGCTGGACCTGACCTGGTACCTGCAACAGATCACCAACCTGCCGGTGGAGAACAACTGGCAGGCGCTGGCCCGCGAGGCGTTCCGCGACGACCTCGACTGGCAGCAGCGGGCGATCACCGTCTCGGTGTTGCAGATGCAGGACGGACCGAAGGAGGTCGAGGCTCGCGTCGGCCTGTGGCTGGAACAGCACCTGCCGCTGGTCGAGCGCTGGCGGGCGATGCTGGTCGAACTGCGTGCCGCGTCGGGTACCGACTACGCCATGTACGCCGTGGCCAACCGCGAGCTGATGGACCTGGCGCAGAGCAGCCAGCACGGTGTCTGCATCCCCTGA

Protein Properties

Protein Residues:

1620

Protein Molecular Weight:

182.6 kDa

Protein Theoretical pI:

6.14

Hydropathicity (GRAVY score):

-0.225

Charge at pH 7 (predicted):

-19.05

Protein Sequence:

>PA3068
MAFFTAASKADFQHQLQTALAQHLGDKALPQVTLFAEQFFSLISLDELTQRRLSDLVGCTLSAWRLLERFDRDQPEVRVYNPDYEKHGWQSTHTAVEVLHPDLPFLVDSVRMELNRRGYSIHTLQTNVLSVRRSAKGELKEILPKGSQGKDVSQESLMYLEIDRCAHAGELRALEKAILEVLGEVRVTVADFEPMKAKARELLTWLGKAKLKVPAEELKEVRSYLEWLLDNHFTFLGYEEFSVADEADGGRMVYDEKSFLGLTRLLRAGLSKDDLHIEDYAVAYLREPVLLSFAKAAHPSRVHRPAYPDYVSIRELDGKGRVIRECRFMGLFTSSVYNESVNDIPFIRGKVAEVMRRSGFDTKAHLGKELAQVLEVLPRDDLFQTPVDELFSTALAIVRIQERNKIRVFLRKDPYGRFCYCLAYVPRDVYSTETRLKIQQVLMERLQASDCEFWTFFSESVLARVQFILRVDPKSRIDIDPARLEEEVIQACRSWQDDYSSLVVENLGEAKGTNVLADFPKGFPAGYRERFAPHFAVVDLQHLLSLSEQRPLVMSFYQPLAQGEQQLHCKLYHADTPLALSDVLPILENLGLRVLGEFPYRLRHQNGREYWIHDFAFTYAEGLDVDIQQLNEILQDAFVHIVSGDAENDAFNRLVLTANLPWRDVALLRAYARYLKQIRLGFDLGYIASALNAHTDIARELVRLFKTRFYLARKLTAEDLEDKQQKLEQAILGALDEVQVLNEDRILRRYLDLIKATLRTNFYQPDGNGQNKSYFSFKFNPKAIPELPRPVPKYEIFVYSPRVEGVHLRGGKVARGGLRWSDREEDFRTEVLGLVKAQQVKNAVIVPVGAKGGFVPRRLPLGGSRDEIQAEAIACYRIFISGLLDITDNLKEGEVVPPANVVRHDEDDPYLVVAADKGTATFSDIANGIAAEYGFWLGDAFASGGSAGYDHKGMGITAKGAWVSVQRHFRERGIDVQKDNISVIGIGDMAGDVFGNGLLMSDKLQLVAAFNHMHIFIDPNPDAASSFVERQRLFNLPRSSWADYDAKLISAGGGIFLRSAKSIAITPEMKARFDIQADRLAPTELIHALLKAPVDLLWNGGIGTYVKSSKETHADVGDKANDGLRVDGRELRAKVVGEGGNLGMTQLARVEFGLHGGANNTDFIDNAGGVDCSDHEVNIKILLNEVVQAGDMTEKQRNALLVKMTDAVGALVLGNNYKQTQALSLAQRRARERIAEYKRLMGDLEARGKLDRALEFLPSDEELAERISAGQGLTRAELSVLISYSKIDLKESLLKSLVPDDDYLTRDMETAFPALLAEKFGDAMRRHRLKREIVSTQIANDLVNHMGITFVQRLKESTGMSAANVAGAYVIVRDVFHLPHWFRQIENLDYQVPADIQLTLMDELMRLGRRATRWFLRSRRNELDAARDVAHFGPRIAALGLKLNELLEGPTRELWQARYQTYVDAGVPELLARMVAGTSHLYTLLPIIEASDVTGQDTAEVAKAYFAVGSALDLTWYLQQITNLPVENNWQALAREAFRDDLDWQQRAITVSVLQMQDGPKEVEARVGLWLEQHLPLVERWRAMLVELRAASGTDYAMYAVANRELMDLAQSSQHGVCIP

References

External Links:

Resource	Link
Genome ID:	PA3068
Entrez Gene ID:	878664
NCBI Protein ID:	15598264

General Reference:

PaperBLAST - Find papers about PA3068 and its homologs

NAD-dependent glutamate dehydrogenase (PA3068)