| Identification |
| Name: |
Phenylalanyl-tRNA synthetase alpha chain |
| Synonyms: |
- Phenylalanine--tRNA ligase alpha chain
- PheRS
|
| Gene Name: |
pheS |
| Enzyme Class: |
|
| Biological Properties |
| General Function: |
Involved in nucleotide binding |
| Specific Function: |
ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe) |
| Cellular Location: |
Cytoplasm |
| KEGG Pathways: |
|
| KEGG Reactions: |
|
 | + |  | + | tRNA(Phe) | + | tRNA(Phe) | ↔ |  | + | L-Phenylalanyl-tRNA(Phe) | + |  | + | L-Phenylalanyl-tRNA(Phe) |
| | |
| + | | + | tRNA(Phe) | ↔ | | + | | + | L-Phenylalanyl-tRNA(Phe) |
| |
|
| SMPDB Reactions: |
|
L-Phenylalanine | + | | + |  | + | tRNA(Phe) | + | | → | | + | Pyrophosphate | + | L-phenylalanyl-tRNA(Phe) |
| |
|
| PseudoCyc/BioCyc Reactions: |
|
| Complex Reactions: |
|
| + | | + | tRNA(Phe) | → | | + | | + | L-phenylalanyl-tRNA(Phe) |
| | |
| + | | + | tRNA(Phe) | → | | + | | + | L-phenylalanyl-tRNA(Phe) |
| |
|
| Transports: |
Not Available |
| Metabolites: |
|
| GO Classification: |
| Component |
|---|
| cell part | | cytoplasm | | intracellular part | | Function |
|---|
| adenyl nucleotide binding | | adenyl ribonucleotide binding | | aminoacyl-tRNA ligase activity | | ATP binding | | binding | | catalytic activity | | ligase activity | | ligase activity, forming aminoacyl-tRNA and related compounds | | ligase activity, forming carbon-oxygen bonds | | nucleic acid binding | | nucleoside binding | | nucleotide binding | | phenylalanine-tRNA ligase activity | | purine nucleoside binding | | RNA binding | | tRNA binding | | Process |
|---|
| biosynthetic process | | cellular macromolecule biosynthetic process | | cellular macromolecule metabolic process | | macromolecule biosynthetic process | | macromolecule metabolic process | | metabolic process | | ncRNA metabolic process | | phenylalanyl-tRNA aminoacylation | | RNA metabolic process | | translation | | tRNA aminoacylation | | tRNA aminoacylation for protein translation | | tRNA metabolic process |
|
| Gene Properties |
| Locus tag: |
PA2740 |
| Strand: |
- |
| Entrez Gene ID: |
882970 |
| Accession: |
NP_251430.1 |
| GI: |
15597936 |
| Sequence start: |
3102529 |
| Sequence End: |
3103545 |
| Sequence Length: |
1016 |
| Gene Sequence: |
>PA2740
ATGGAAAACCTGGATGCGCTGGTCTCTCAAGCATTGGAGGCTGTGCGACACACCGAAGACGTCAATGCCCTGGAGCAGATCCGGGTTCACTACCTCGGCAAGAAAGGCGAACTGACCCAGGTGATGAAGACCCTGGGCGACCTGCCGGCCGAAGAGCGGCCGAAGGTTGGCGCGCTGATCAACGTGGCCAAGGAAAAGGTCCAGGATGTGCTGAACGCGCGTAAGACCGAGCTGGAAGGGGCCGCGCTGGCCGCCCGGCTGGCCGCGGAGCGCATCGATGTCACCCTGCCCGGTCGTGGCCAGCTGAGCGGCGGCCTGCATCCGGTCACCCGCACGCTGGAGCGCATCGAGCAGTGCTTCAGCCGCATCGGCTATGAAGTCGCCGAAGGCCCGGAAGTCGAAGACGACTACCACAACTTCGAAGCGCTCAACATTCCGGGCCACCACCCGGCGCGTGCCATGCACGACACTTTCTATTTCAATGCGAACATGCTGCTGCGTACCCACACCTCACCGGTGCAGGTGCGGACCATGGAGTCCCAGCAGCCGCCGATCCGCATTGTCTGCCCGGGGCGCGTCTACCGCTGCGACTCCGACCTGACCCACTCGCCGATGTTCCACCAGGTGGAAGGCCTGTTGGTGGACGAGGGTGTCAGCTTCGCCGACCTCAAGGGCACCATCGAGGAATTCCTCCGCGCCTTCTTCGAGAAGCAGCTTGAAGTGCGCTTCCGTCCGTCCTTCTTCCCCTTCACCGAGCCCTCGGCCGAAGTGGACATTCAGTGCGTGATCTGCAGCGGCAACGGCTGCCGCGTGTGCAAGCAGACCGGCTGGCTGGAAGTCATGGGTTGCGGCATGGTGCACCCGAACGTGCTGCGCATGTCCAACATCGATCCCGAGAAATTCCAGGGCTTCGCCTTCGGCATGGGCGCCGAGCGCCTGGCCATGCTGCGCTACGGGGTGAACGACCTGCGTCTGTTCTTCGATAACGATCTGCGCTTCCTCGGACAATTCCGCTAG |
| Protein Properties |
| Protein Residues: |
338 |
| Protein Molecular Weight: |
38.1 kDa |
| Protein Theoretical pI: |
5.79 |
| Hydropathicity (GRAVY score): |
-0.241 |
| Charge at pH 7 (predicted): |
-7.58 |
| Protein Sequence: |
>PA2740
MENLDALVSQALEAVRHTEDVNALEQIRVHYLGKKGELTQVMKTLGDLPAEERPKVGALINVAKEKVQDVLNARKTELEGAALAARLAAERIDVTLPGRGQLSGGLHPVTRTLERIEQCFSRIGYEVAEGPEVEDDYHNFEALNIPGHHPARAMHDTFYFNANMLLRTHTSPVQVRTMESQQPPIRIVCPGRVYRCDSDLTHSPMFHQVEGLLVDEGVSFADLKGTIEEFLRAFFEKQLEVRFRPSFFPFTEPSAEVDIQCVICSGNGCRVCKQTGWLEVMGCGMVHPNVLRMSNIDPEKFQGFAFGMGAERLAMLRYGVNDLRLFFDNDLRFLGQFR |
| References |
| External Links: |
|
| General Reference: |
PaperBLAST - Find papers about PA2740 and its homologs
|
