Phenylalanyl-tRNA synthetase beta chain (PA2739)

Identification
Name: Phenylalanyl-tRNA synthetase beta chain
Synonyms:
  • Phenylalanine--tRNA ligase beta chain
  • PheRS
Gene Name: pheT
Enzyme Class:
Biological Properties
General Function: Involved in RNA binding
Specific Function: ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe)
Cellular Location: Cytoplasm
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb+tRNA(Phe)+tRNA(Phe) ↔ Thumb+L-Phenylalanyl-tRNA(Phe)+Thumb+L-Phenylalanyl-tRNA(Phe)
Adenosine triphosphate + L-Phenylalanine + tRNA(Phe) + tRNA(Phe) ↔ Adenosine monophosphate + L-Phenylalanyl-tRNA(Phe) + Pyrophosphate + L-Phenylalanyl-tRNA(Phe)
ReactionCard
Thumb+Thumb+tRNA(Phe) ↔ Thumb+Thumb+L-Phenylalanyl-tRNA(Phe)
Adenosine triphosphate + L-Phenylalanine + tRNA(Phe) ↔ Adenosine monophosphate + Pyrophosphate + L-Phenylalanyl-tRNA(Phe)
ReactionCard
SMPDB Reactions:
L-Phenylalanine+Thumb+Thumb+tRNA(Phe)+Thumb → Thumb+Pyrophosphate+L-phenylalanyl-tRNA(Phe)
L-Phenylalanine + Adenosine triphosphate + Hydrogen ion + tRNA(Phe) + L-Phenylalanine → Adenosine monophosphate + Pyrophosphate + L-phenylalanyl-tRNA(Phe)
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb+Thumb+tRNA(Phe)+tRNA(Phe) ↔ Thumb+L-Phenylalanyl-tRNA(Phe)+Thumb+L-Phenylalanyl-tRNA(Phe)
Adenosine triphosphate + L-Phenylalanine + tRNA(Phe) + tRNA(Phe) ↔ Adenosine monophosphate + L-Phenylalanyl-tRNA(Phe) + Pyrophosphate + L-Phenylalanyl-tRNA(Phe)
ReactionCard
Thumb+Thumb+tRNA(Phe) ↔ Thumb+Thumb+L-Phenylalanyl-tRNA(Phe)
Adenosine triphosphate + L-Phenylalanine + tRNA(Phe) ↔ Adenosine monophosphate + Pyrophosphate + L-Phenylalanyl-tRNA(Phe)
ReactionCard
Thumb+Thumb+tRNA(Phe) → Thumb+Thumb+L-phenylalanyl-tRNA(Phe)
Adenosine triphosphate + L-Phenylalanine + tRNA(Phe) → Adenosine monophosphate + Pyrophosphate + L-phenylalanyl-tRNA(Phe)
ReactionCard
L-Phenylalanine+Thumb+Thumb+tRNA(Phe)+Thumb → Thumb+Pyrophosphate+L-phenylalanyl-tRNA(Phe)
L-Phenylalanine + Adenosine triphosphate + Hydrogen ion + tRNA(Phe) + L-Phenylalanine → Adenosine monophosphate + Pyrophosphate + L-phenylalanyl-tRNA(Phe)
ReactionCard
Complex Reactions:
Thumb+Thumb+tRNA(Phe) → Thumb+Thumb+L-phenylalanyl-tRNA(Phe)
Adenosine triphosphate + L-Phenylalanine + tRNA(Phe) → Adenosine monophosphate + Pyrophosphate + L-phenylalanyl-tRNA(Phe)
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000014Adenosine monophosphateMetaboCard
PAMDB000148Adenosine triphosphateMetaboCard
PAMDB001633Hydrogen ionMetaboCard
PAMDB000061L-PhenylalanineMetaboCard
PAMDB000633PyrophosphateMetaboCard
GO Classification:
Component
cell part
cytoplasm
intracellular part
Function
adenyl nucleotide binding
adenyl ribonucleotide binding
aminoacyl-tRNA ligase activity
ATP binding
binding
catalytic activity
cation binding
ion binding
ligase activity
ligase activity, forming aminoacyl-tRNA and related compounds
ligase activity, forming carbon-oxygen bonds
magnesium ion binding
metal ion binding
nucleic acid binding
nucleoside binding
nucleotide binding
phenylalanine-tRNA ligase activity
purine nucleoside binding
RNA binding
tRNA binding
Process
biosynthetic process
cellular macromolecule biosynthetic process
cellular macromolecule metabolic process
macromolecule biosynthetic process
macromolecule metabolic process
metabolic process
ncRNA metabolic process
phenylalanyl-tRNA aminoacylation
RNA metabolic process
translation
tRNA aminoacylation
tRNA aminoacylation for protein translation
tRNA metabolic process
tRNA processing
Gene Properties
Locus tag: PA2739
Strand: -
Entrez Gene ID: 882969
Accession: NP_251429.1
GI: 15597935
Sequence start: 3100116
Sequence End: 3102494
Sequence Length: 2378
Gene Sequence: 
>PA2739
ATGAAATTCAGTGAAAAGTGGCTGCGGAGCTGGGCAAATCCGCAGGTTTCCCATGACGAGCTGGTCGCTCGCCTGTCCATGGTCGGCCTCGAGGTTGACGCCGACCTGCCGGTCGCCGGCGCCTTCAGCGGCGTGGTGGTCGGCGAGGTGCTCTCGACCGAACAGCATCCGGACGCCGACAAGCTGCGCGTCTGCCAGGTCAGCAACGGCAGCGAGACCTTCCAGGTCGTCTGCGGTGCGCCCAACGTGCGCGCGGGCCTGAAGATTCCGTTCGCCATGATCGGCGCCGAACTGCCGGACGACTTCAAGATCAAGAAAGCCAAGCTGCGCGGCGTCGAGTCCTTCGGCATGCTCTGCTCGGCCAAGGAATTGCAGATCAGCGAAGAGAACGCCGGTCTGCTCGAGCTGCCGGCTGACGCGCCGGTCGGCCAGGACGTCCGCACCTACCTGGAGCTGGCCGACTACACCATCGAGGTCGGCCTGACCCCGAACCGCGGTGACTGCCTGTCGCTCGCCGGCCTGGCCCGCGAAGTCAGCGCCATCTACGACGTTCCGCTGGCGCCGGTGGCGGTGGACGCGGTCGCCGCGCAGCACGACGAGACCCGTCCGGTCGAACTCGCCGCGCCGGCTGCCTGCCCGCGCTACCTCGGCCGGGTGATCCGCAACGTCGACCTGAGCCGGCCGACCCCGTTGTGGATGGTCGAGCGCCTGCGCCGTTCCGACATCCGCAGCATCGACCCGGTGGTCGACGTCACCAACTACGTGATGATCGAACTGGGCCAGCCGATGCATGCCTTCGACCTTGCCGAGATCAACGGCGGCGTGCGCGTGCGCATGGCCGAGGACGGCGAGAAACTGGTCCTGCTCGACGGTCAGGAAATCACCCTGCGCGCCGACACCCTGGTGATCGCCGACCACCAGCGCGCCCTGGCCATCGCCGGGGTGATGGGCGGCGAGCACAGCGGCGTCAGCGACAGCACCCGCGACCTGTTCCTCGAAGCCGCGTTCTTCGACACCATCGCCCTGGCCGGCAAGGCCCGCTCCTATGGCCTGCACACCGACTCCTCGCATCGCTTCGAGCGCGGCGTCGACAGCCAGTTGGCGCGCAAGGCCATGGAGCGCGCGACGCGCCTGATCCTCGACATCGTCGGCGGTGAACCAGGGCCGATCGTCGAGCAGGTCAGCGAAGCGCACCTACCGAAGGTCGCGCCGATCACCCTGCGCGCCGAGCGCGTGACCCAGATGCTCGGCATGCCGCTGGACGCCGCCGAGATCGTGCGCCTGCTGCAAGCCCTGGAACTAACGGTGGTAGCCGACGGGGAAGGGCAGTGGTCGGTCGGCGTACCGAGCCATCGCTTCGACATTTCCCTGGAAGTCGACCTGATCGAGGAACTGGCCCGTCTCTACGGATACAATCGCCTGCCGGTGCGCTACCCGCAGGCGCGCCTGGCGCCGAACAACAAGCCGGAAGCGCGCGCCGCGCTGCCGCTGCTGCGGCGCCTGCTGGTCGCCCGCGGCTACCAGGAAGCGATCACCTTCAGCTTCATCGATCCGGCCCTGTTCGAACTGTTCGATCCGGGCACCCAGCCGCTGACCCTGGCCAACCCGATCTCCGCCGACATGGCGGCGATGCGTTCCAGCCTCTGGCCGGGCCTGGTCAAGGCGCTGCAGCACAACCTCAACCGCCAGCAGTCGCGGGTCCGCCTGTTTGAAAGTGGCCTGCGCTTCGTCGGTCAACTGGAAGGCCTGAAGCAGGAAGCCATGCTCGCCGGCGCCATCTGCGGCAAGCGCCTGCCGGAAGGCTGGGCCAATGGTCGTGACGGCGTGGACTTCTTCGACGCCAAGGCCGATGTCGAGGCAGTGCTGGCCAGTGCTGGTGCCCTCGGCGACTTCAGCTTCGTGCCCGGCGAGCACCCGGCGCTGCACCCGGGGCAGACCGCACGCATCGAGCGGGAAGGGCGGCTGGTCGGCTACCTGGGTGCGCTACATCCGGAATTGGCGAAGAAACTCGACCTCGAGCAGCCGGTGTTCCTCTTCGAGCTGCTGCTGGCCGAAGTGGTCGACGGCCACCTGCCGAAGTTCCGCGAGCTGTCGCGCTTCCCCGAAGTGCGCCGCGACCTGGCGCTGCTGGTGGATCAGGACGTGCCGGCACAAGACATCCTGACACAAATCCGTGCGGCGGCCGGCGAATGGCTGACGGACCTCAGGCTGTTTGATGTGTATCACGGTAAAGGCATTGATCCGCATAGAAAAAGCCTTGCCGTCGGCTTGACCTGGCAGCATCCATCGCGCACTCTTAATGACGATGAAGTCAATAGCACGACGCAGAACATCGTCACGTCGTTGGAAGAAAGGTTCAATGCCACGTTAAGGAAATAG
Protein Properties
Protein Residues: 792
Protein Molecular Weight: 86.8 kDa
Protein Theoretical pI: 5.08
Hydropathicity (GRAVY score): -0.067
Charge at pH 7 (predicted): -21.78
Protein Sequence: 
>PA2739
MKFSEKWLRSWANPQVSHDELVARLSMVGLEVDADLPVAGAFSGVVVGEVLSTEQHPDADKLRVCQVSNGSETFQVVCGAPNVRAGLKIPFAMIGAELPDDFKIKKAKLRGVESFGMLCSAKELQISEENAGLLELPADAPVGQDVRTYLELADYTIEVGLTPNRGDCLSLAGLAREVSAIYDVPLAPVAVDAVAAQHDETRPVELAAPAACPRYLGRVIRNVDLSRPTPLWMVERLRRSDIRSIDPVVDVTNYVMIELGQPMHAFDLAEINGGVRVRMAEDGEKLVLLDGQEITLRADTLVIADHQRALAIAGVMGGEHSGVSDSTRDLFLEAAFFDTIALAGKARSYGLHTDSSHRFERGVDSQLARKAMERATRLILDIVGGEPGPIVEQVSEAHLPKVAPITLRAERVTQMLGMPLDAAEIVRLLQALELTVVADGEGQWSVGVPSHRFDISLEVDLIEELARLYGYNRLPVRYPQARLAPNNKPEARAALPLLRRLLVARGYQEAITFSFIDPALFELFDPGTQPLTLANPISADMAAMRSSLWPGLVKALQHNLNRQQSRVRLFESGLRFVGQLEGLKQEAMLAGAICGKRLPEGWANGRDGVDFFDAKADVEAVLASAGALGDFSFVPGEHPALHPGQTARIEREGRLVGYLGALHPELAKKLDLEQPVFLFELLLAEVVDGHLPKFRELSRFPEVRRDLALLVDQDVPAQDILTQIRAAAGEWLTDLRLFDVYHGKGIDPHRKSLAVGLTWQHPSRTLNDDEVNSTTQNIVTSLEERFNATLRK
References
External Links:
Resource Link
Genome ID: PA2739
Entrez Gene ID: 882969
NCBI Protein ID: 15597935
General Reference: PaperBLAST - Find papers about PA2739 and its homologs