Ferrienterobactin receptor (PA2688)

Identification
Name: Ferrienterobactin receptor
Synonyms:
  • Enterobactin outer-membrane receptor
Gene Name: fepA
Enzyme Class: Not Available
Biological Properties
General Function: Involved in receptor activity
Specific Function: This protein is involved in the initial step of iron uptake by binding ferrienterobactin (Fe-ENT), an iron chelatin siderophore that allows E.coli to extract iron from the environment. FepA also acts as a receptor for colicins B and D
Cellular Location: Cell outer membrane; Multi-pass membrane protein
KEGG Pathways:
  • Biosynthesis of siderophore group nonribosomal peptides PW000760
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Complex Reactions: Not Available
    Transports:
    Metabolites:
    PAMDB IDNameView
    PAMDB001768Ferric enterobactinMetaboCard
    PAMDB001633Hydrogen ionMetaboCard
    GO Classification:
    Component
    cell part
    membrane
    Function
    binding
    cation binding
    cation transmembrane transporter activity
    di-, tri-valent inorganic cation transmembrane transporter activity
    inorganic cation transmembrane transporter activity
    ion binding
    ion transmembrane transporter activity
    iron ion binding
    iron ion transmembrane transporter activity
    metal ion binding
    molecular transducer activity
    receptor activity
    siderophore-iron transmembrane transporter activity
    signal transducer activity
    substrate-specific transmembrane transporter activity
    transition metal ion binding
    transmembrane transporter activity
    transporter activity
    Process
    establishment of localization
    siderophore transport
    transport
    Gene Properties
    Locus tag: PA2688
    Strand: +
    Entrez Gene ID: 882784
    Accession: NP_251378.1
    GI: 15597884
    Sequence start: 3040242
    Sequence End: 3042482
    Sequence Length: 2240
    Gene Sequence: 
    >PA2688
ATGTCCTCACGCGCCCTTCCCGCCGTTCCCTTCCTGCTGCTGTCCAGTTGCCTGCTCGCCAACGCCGTACACGCCGCCGGCCAGGGCGACGGCTCCGTCATCGAGCTGGGCGAGCAGACCGTGGTCGCCACCGCCCAGGAGGAAACCAAGCAGGCGCCGGGGGTTTCCATCATCACCGCCGAGGACATCGCCAAGCGACCGCCGAGCAACGACCTGTCGCAGATCATCCGGACCATGCCGGGGGTCAACCTGACCGGCAACAGCTCCAGCGGCCAGCGTGGAAACAACCGGCAGATCGACATCCGCGGCATGGGCCCGGAGAACACCCTGATCCTGGTCGACGGCAAGCCGGTCAGCTCGCGCAACTCGGTGCGCTACGGCTGGCGCGGCGAGCGCGACAGCCGCGGCGACACCAACTGGGTGCCGGCCGACCAGGTCGAGCGCATCGAAGTGATCCGCGGCCCGGCGGCGGCGCGCTACGGCAACGGCGCGGCGGGCGGCGTGGTGAACATCATCACCAAGCAGGCCGGCGCGGAAACCCACGGTAATCTCAGCGTCTACAGCAATTTCCCGCAACACAAGGCCGAAGGCGCCAGCGAACGGATGAGCTTCGGTCTCAACGGGCCGCTCACGGAAAACCTCAGCTACCGCGTCTACGGCAACATCGCCAAGACCGACTCGGACGACTGGGACATCAACGCCGGCCACGAATCCAACCGTACCGGCAAGCAGGCCGGCACCCTCCCCGCCGGTCGCGAAGGCGTGCGCAACAAGGACATCGACGGGCTGCTCAGCTGGCGCCTGACGCCCGAGCAGACCCTCGAGTTCGAGGCCGGCTTCAGCCGCCAGGGCAACATCTACACCGGCGACACGCAGAACACCAACAGCAACAACTACGTGAAGCAGATGCTCGGCCACGAGACCAACCGCATGTACCGCGAGACCTACTCGGTCACCCATCGCGGCGAATGGGACTTCGGCAGCTCGCTGGCCTACCTGCAGTACGAGAAGACCCGCAACAGCCGGATCAACGAAGGCCTGGCCGGCGGCACCGAAGGTATCTTCGACCCCAACAACGCCGGCTTCTACACCGCCACCCTGCGCGACCTGACCGCCCACGGCGAGGTCAACCTGCCGCTGCACCTGGGCTACGAGCAGACCCTGACCCTCGGCAGCGAGTGGACCGAGCAGAAGCTCGACGACCCCAGCTCCAACACCCAGAACACCGAGGAAGGCGGCTCGATCCCCGGTCTCGCCGGAAAGAACCGCAGCAGCAGTTCCTCGGCGCGGATCTTCTCGCTGTTCGCCGAGGACAACATCGAGCTGATGCCCGGCACCATGCTCACCCCAGGCCTGCGCTGGGACCACCACGACATCGTCGGCGACAACTGGAGCCCATCGCTGAACCTGTCCCACGCGCTCACCGAGCGGGTCACCCTGAAGGCCGGTATCGCCCGCGCCTACAAGGCCCCCAACCTGTACCAGCTGAACCCCGACTACCTGCTCTACAGCCGTGGCCAGGGTTGCTACGGGCAAAGCACCAGTTGCTACCTGCGCGGCAACGACGGCCTCAAGGCCGAGACCAGCGTGAACAAGGAACTGGGCATCGAGTACAGCCACGACGGCCTGGTAGCGGGGCTGACCTACTTCCGCAACGACTACAAGAACAAGATCGAATCCGGCCTGTCACCGGTCGACCACGCCAGCGGCGGCAAGGGCGACTACGCCAACGCGGCGATCTACCAGTGGGAGAACGTGCCCAAGGCGGTGGTCGAGGGCCTCGAAGGCACCCTGACCCTGCCCCTGGCCGACGGCCTGAAGTGGAGCAACAACCTCACCTACATGCTGCAATCGAAGAACAAGGAAACCGGCGACGTGCTCTCGGTGACGCCGCGCTACACCCTCAACTCGATGCTCGACTGGCAGGCCACCGACGACCTCTCGCTGCAAGCCACGGTCACCTGGTACGGCAAGCAGAAGCCGAAGAAATACGACTATCACGGCGACCGTGTCACCGGCAGCGCCAACGACCAGCTCTCGCCCTACGCCATCGCCGGCCTCGGCGGCACCTATCGGTTGAGCAAGAACCTGAGCCTCGGCGCCGGCGTCGACAACCTGTTCGACAAGCGCCTGTTCCGCGCCGGCAATGCCCAGGGCGTGGTCGGCATCGACGGGGCCGGCGCGGCGACCTACAACGAGCCCGGACGGACCTTCTATACCAGCCTGACCGCGTCGTTCTGA
    Protein Properties
    Protein Residues: 746
    Protein Molecular Weight: 81 kDa
    Protein Theoretical pI: 5.8
    Hydropathicity (GRAVY score): -0.557
    Charge at pH 7 (predicted): -9.7
    Protein Sequence: 
    >PA2688
MSSRALPAVPFLLLSSCLLANAVHAAGQGDGSVIELGEQTVVATAQEETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLTGNSSSGQRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQVERIEVIRGPAAARYGNGAAGGVVNIITKQAGAETHGNLSVYSNFPQHKAEGASERMSFGLNGPLTENLSYRVYGNIAKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDIDGLLSWRLTPEQTLEFEAGFSRQGNIYTGDTQNTNSNNYVKQMLGHETNRMYRETYSVTHRGEWDFGSSLAYLQYEKTRNSRINEGLAGGTEGIFDPNNAGFYTATLRDLTAHGEVNLPLHLGYEQTLTLGSEWTEQKLDDPSSNTQNTEEGGSIPGLAGKNRSSSSSARIFSLFAEDNIELMPGTMLTPGLRWDHHDIVGDNWSPSLNLSHALTERVTLKAGIARAYKAPNLYQLNPDYLLYSRGQGCYGQSTSCYLRGNDGLKAETSVNKELGIEYSHDGLVAGLTYFRNDYKNKIESGLSPVDHASGGKGDYANAAIYQWENVPKAVVEGLEGTLTLPLADGLKWSNNLTYMLQSKNKETGDVLSVTPRYTLNSMLDWQATDDLSLQATVTWYGKQKPKKYDYHGDRVTGSANDQLSPYAIAGLGGTYRLSKNLSLGAGVDNLFDKRLFRAGNAQGVVGIDGAGAATYNEPGRTFYTSLTASF
    References
    External Links:
    Resource Link
    Genome ID: PA2688
    Entrez Gene ID: 882784
    NCBI Protein ID: 15597884
    General Reference: PaperBLAST - Find papers about PA2688 and its homologs