| Identification |
| Name: |
Deoxyguanosinetriphosphate triphosphohydrolase |
| Synonyms: |
- dGTP triphosphohydrolase
- dGTPase
|
| Gene Name: |
dgt |
| Enzyme Class: |
|
| Biological Properties |
| General Function: |
Involved in magnesium ion binding |
| Specific Function: |
dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs |
| Cellular Location: |
Cytoplasmic |
| KEGG Pathways: |
|
| KEGG Reactions: |
|
| SMPDB Reactions: |
Not Available |
| PseudoCyc/BioCyc Reactions: |
|
| Complex Reactions: |
|
| Transports: |
Not Available |
| Metabolites: |
|
| GO Classification: |
| Function |
|---|
| binding | | catalytic activity | | cation binding | | dGTPase activity | | hydrolase activity | | hydrolase activity, acting on ester bonds | | ion binding | | magnesium ion binding | | metal ion binding | | phosphoric ester hydrolase activity | | triphosphoric monoester hydrolase activity | | Process |
|---|
| cellular nitrogen compound metabolic process | | GTP metabolic process | | metabolic process | | nitrogen compound metabolic process | | nucleobase, nucleoside and nucleotide metabolic process | | nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | | nucleoside phosphate metabolic process | | nucleotide metabolic process | | purine nucleoside triphosphate metabolic process | | purine nucleotide metabolic process | | purine ribonucleoside triphosphate metabolic process |
|
| Gene Properties |
| Locus tag: |
PA1124 |
| Strand: |
+ |
| Entrez Gene ID: |
880761 |
| Accession: |
NP_249815.1 |
| GI: |
15596321 |
| Sequence start: |
1216671 |
| Sequence End: |
1218167 |
| Sequence Length: |
1496 |
| Gene Sequence: |
>PA1124
ATGCCAGGGGCCGTGGATTTCAAGGAGCGGATATCCCGCCAGCGTCCGCATGACAGGGAAACCTACGGACATGCCGGGAATACCGATCTGCAAGACATCGTCTACCAGTTGGAAAGCGACCGCGGGCGCATCGTCAATTCCGCCGCCGTGCGTCGCTTGCAGCAGAAGACCCAGGTCTTCCCGCTGGAGCGCAACGCGGCGGTGCGCAGCCGCCTGACCCATTCCCTGGAAGTGCAGCAGACCGGGCGTTTCATCGTCCGCACGCTGTTCCGCCAACTGGGCCCGCGTGCCGCGGAGGTCGGCCTGGACGGGCTGGAAGGCGCGCTGGAAAGCCTGGTGGAAATGGCCTGCCTGATGCACGACGTCGGCAATCCGCCGTTCGGTCATTTCGGCGAGTACGCCATCAACGACTGGTTCGAACGCAACCTCGACGCCCTGTTCGAGCGCCGCATACCGCCGGGCCAGGGCGACGGCCTGTTGCAGCAGCGCATGCTCACCGACCTCAAGCACTTCGAAGGCAACGCCCAGGCCATCCGCCTGGTGGTGAAGCTGCTGCGCCTGAACCTCACCTACACGCAGACCGCCGGCCTGCTCAAGTACGTGCGCCCGGCCTACGAGCCGAAGCCGGACAAGGCGGCGGCGAACCACTACCTGAACAAGAAGCCGGGCTTCTATCTTTCCGAGGAAGCCTTCGTCGACGAACTGCGCCGAGTCCTCGGCATGCGCCCGGGCACTCGCCACCCTGTGGCCTACATCATGGAAGCGGCCGACGATATCTCCTATTGCCTGGCCGATATCGAAGACTCGGTGGAAAAAGGCATCCTCGACATCCGTCAATTGGCGGATCTGCTGGTGAAGAAGTTTGCCGTCCACCATTCGCCGGACGCGCCGATTCCCGGCGACGCGGACAACATGAGCTTCCAGCGGATGGTCGACTACTCGCTGGAAAAGGCCGAGCGGGAGCCGATCAACAAGGTCAGCGAATTCTTCATCCGCCTGCGGGTGAAAATGATCCACCCGCTGGTCCAGCACGCCGCCCAGCAGTTCATCGACAACTTCGAAGCGGTTCATGCCGGCACCCTCGGCCGCGCGCTGATGGAGGACGGCAGCCTGCCGCACGCCATCGTCCAGACGTTCAAGGACGTGGCCATGGAATGGGTGTTCTGCCATCCGGAGGTGGAAACCCTGGAATTGCAGGGCTACCGCATCATTCAGGGGTTGCTGGATTTCTACGCGCCGCTGCTGCGCCTGCCGGCCGAGGAGTTCCAGGCCCTCGCCGAAGGTCGCCAGGCCGCCGCGCCGCATCCGCAACTGCTGGTTCGGCGCCTGCCGAGCCAGCAGATCAAGGCTTACCTGGAGGCCATGAAAGGTGTGGCGGAGGACCCGTTGCAGCGGCAGTGGGAGTTCTACCACCGCTGCCGCATGCTCCAGGATTTCGTCAGCGGCATGACCGACCAGCATGCCCAGGACGAATACCGCGCGTTGTCCGCGCTGTAA |
| Protein Properties |
| Protein Residues: |
498 |
| Protein Molecular Weight: |
56.7 kDa |
| Protein Theoretical pI: |
6.52 |
| Hydropathicity (GRAVY score): |
-0.353 |
| Charge at pH 7 (predicted): |
-4.77 |
| Protein Sequence: |
>PA1124
MPGAVDFKERISRQRPHDRETYGHAGNTDLQDIVYQLESDRGRIVNSAAVRRLQQKTQVFPLERNAAVRSRLTHSLEVQQTGRFIVRTLFRQLGPRAAEVGLDGLEGALESLVEMACLMHDVGNPPFGHFGEYAINDWFERNLDALFERRIPPGQGDGLLQQRMLTDLKHFEGNAQAIRLVVKLLRLNLTYTQTAGLLKYVRPAYEPKPDKAAANHYLNKKPGFYLSEEAFVDELRRVLGMRPGTRHPVAYIMEAADDISYCLADIEDSVEKGILDIRQLADLLVKKFAVHHSPDAPIPGDADNMSFQRMVDYSLEKAEREPINKVSEFFIRLRVKMIHPLVQHAAQQFIDNFEAVHAGTLGRALMEDGSLPHAIVQTFKDVAMEWVFCHPEVETLELQGYRIIQGLLDFYAPLLRLPAEEFQALAEGRQAAAPHPQLLVRRLPSQQIKAYLEAMKGVAEDPLQRQWEFYHRCRMLQDFVSGMTDQHAQDEYRALSAL |
| References |
| External Links: |
|
| General Reference: |
PaperBLAST - Find papers about PA1124 and its homologs
|
