Fumarate hydratase class II (PA0854)

Identification
Name: Fumarate hydratase class II
Synonyms:
  • Fumarase C
Gene Name: fumC
Enzyme Class:
Biological Properties
General Function: Involved in fumarate hydratase activity
Specific Function: (S)-malate = fumarate + H(2)O
Cellular Location: Cytoplasm
KEGG Pathways:
KEGG Reactions:
Thumb+Thumb ↔ Thumb
Fumaric acid + Water ↔ L-Malic acid
ReactionCard
SMPDB Reactions:
Thumb+Thumb → L-Malic acid+Thumb
Fumaric acid + Water → L-Malic acid + L-Malic acid
ReactionCard
PseudoCyc/BioCyc Reactions:
Thumb+Thumb ↔ Thumb
Fumaric acid + Water ↔ L-Malic acid
ReactionCard
Complex Reactions:
Thumb → Thumb+Thumb
L-Malic acid → Fumaric acid + Water
ReactionCard
Transports: Not Available
Metabolites:
PAMDB IDNameView
PAMDB000073Fumaric acidMetaboCard
PAMDB000058L-Malic acidMetaboCard
PAMDB000142WaterMetaboCard
GO Classification:
Component
macromolecular complex
protein complex
tricarboxylic acid cycle enzyme complex
Function
carbon-oxygen lyase activity
catalytic activity
fumarate hydratase activity
hydro-lyase activity
lyase activity
Process
acetyl-CoA catabolic process
acetyl-CoA metabolic process
carboxylic acid metabolic process
cellular metabolic process
coenzyme metabolic process
cofactor metabolic process
dicarboxylic acid metabolic process
fumarate metabolic process
metabolic process
organic acid metabolic process
oxoacid metabolic process
tricarboxylic acid cycle
Gene Properties
Locus tag: PA0854
Strand: -
Entrez Gene ID: 878044
Accession: NP_249545.1
GI: 15596051
Sequence start: 932718
Sequence End: 934112
Sequence Length: 1394
Gene Sequence: 
>PA0854
ATGAGCCGGACCGAAACCGATAGCCTGGGCACCATCGAGGTGCCCGACGACGCCTACTGGGGCGCCCAGACCCAGCGTTCGCTGGAGAACTTCGCCATCGGCGGCCAGCGCATGCCGCTCGCCGTGATCCACGCCCTGGCGCTGATCAAGAAAGCCGCCGCGCGGGTCAACGACCACCTCGGCGAACTGCCGCCGGAAGTCGCCCGGCTGATCGAACAGGCCGCCGACGAAGTCCTCGCAGGCCGCCACGACGAACACTTCCCGCTGGTGGTCTGGCAGACCGGCAGCGGCACCCAGACCAACATGAACGTCAACGAGGTGATCGCTGGCCGCGCCAACGAACTGGCCGGCAATCCGCGTGGCGGCAAGTCGCCGGTGCATCCCAACGACCACGTCAACCGCGCGCAGAGTTCCAACGACAGCTTCCCCACCGCCATGCACATCGCCGCCGCCAAGGCCGTGCACGAACAATTGCTGCCGGCCATCGCCGAGCTTTCCGGCGGTCTCGCCGAACAGTCGGCGCGGCACGCCAGCCTGGTCAAGACCGGGCGCACCCACCTGATGGACGCCACGCCGATCACCTTCGGCCAGGAACTCTCGGCCTTCGTCGCCCAGCTCGACTACGCCGAGCGCGCCATCCGCGCGGCGCTGCCGGCGGTCTACCAGTTGGCCCAGGGCGGCACCGCGGTGGGCACCGGGCTCAACGCGCCGAAGGGCTTCGCCGACGCCATCGCCGCGGAAATCGCCGCCGAATCGGGCCTGCCCTTCGTCGCCGCGCCGAACAAGTTCGCCGCCCTGGCCGGCCACGAGCCGCTGGTCATCCTCTCCGGCGCCCTGAAGAGCCTGGCGGTGGCCCTGATGAAGATCGCCAACGACCTGCGCCTGCTCGGTTCCGGCCCACGCGCCGGCTTCGCCGAGGTGAAGCTGCCGGCCAACGAGCCGGGCAGCTCGATCATGCCCGGCAAGGTCAACCCGACCCAGTGCGAGGCGCTGTCGATGCTGGCCTGCCAGGTCATGGGCAACGACAGCACGATTTCCTTCGCCGCCAGCCAGGGCCATCTGCAACTCAACGTGTTCAAGCCGGTGATCGTCTACAACCTGCTGGAGTCCATCCGCCTGCTCGCCGACGGCTGCCGCAACTTCAACAAGCATTGCGTCGCCGGCCTGGAGCCGGACGCCCAGCGCATGGCCGACCTGCTGGAGCGCGGCCTGATGCTGGTCACCGCACTGAACCCGCACATCGGCTACGACAAGGCCGCCGAAATCGCCAAGAAGGCCTACGCCGAAGGCACCACCCTGCGCGCCGCGGCGCTGCAGCTGGGCTACCTGGACGAAGCGCAGTTCGACGAATGGGTACGGCCGGAGCAGATGCTGGAGGCCGGCCACCATGGTTGA
Protein Properties
Protein Residues: 464
Protein Molecular Weight: 49.1 kDa
Protein Theoretical pI: 6.08
Hydropathicity (GRAVY score): -0.035
Charge at pH 7 (predicted): -8.26
Protein Sequence: 
>PA0854
MSRTETDSLGTIEVPDDAYWGAQTQRSLENFAIGGQRMPLAVIHALALIKKAAARVNDHLGELPPEVARLIEQAADEVLAGRHDEHFPLVVWQTGSGTQTNMNVNEVIAGRANELAGNPRGGKSPVHPNDHVNRAQSSNDSFPTAMHIAAAKAVHEQLLPAIAELSGGLAEQSARHASLVKTGRTHLMDATPITFGQELSAFVAQLDYAERAIRAALPAVYQLAQGGTAVGTGLNAPKGFADAIAAEIAAESGLPFVAAPNKFAALAGHEPLVILSGALKSLAVALMKIANDLRLLGSGPRAGFAEVKLPANEPGSSIMPGKVNPTQCEALSMLACQVMGNDSTISFAASQGHLQLNVFKPVIVYNLLESIRLLADGCRNFNKHCVAGLEPDAQRMADLLERGLMLVTALNPHIGYDKAAEIAKKAYAEGTTLRAAALQLGYLDEAQFDEWVRPEQMLEAGHHG
References
External Links:
Resource Link
Genome ID: PA0854
Entrez Gene ID: 878044
NCBI Protein ID: 15596051
General Reference: PaperBLAST - Find papers about PA0854 and its homologs