Lipopolysaccharide export system protein lptA (PA0005)

Identification
Name: Lipopolysaccharide export system protein lptA
Synonyms: Not Available
Gene Name: lptA
Enzyme Class: Not Available
Biological Properties
General Function: Involved in lipopolysaccharide binding
Specific Function: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. May act as a chaperone that facilitates LPS transfer across the aquaeous environment of the periplasm. Interacts specifically with the lipid A domain of LPS
Cellular Location: Periplasm
KEGG Pathways:
  • Lipopolysaccharide biosynthesis PW000831
  • superpathway of phospholipid biosynthesis I (bacteria) PHOSLIPSYN-PWY
  • CDP-diacylglycerol biosynthesis II PWY0-1319
  • phosphatidylglycerol biosynthesis I (plastidic) PWY4FS-7
  • phosphatidylglycerol biosynthesis II (non-plastidic) PWY4FS-8
  • superpathway phosphatidate biosynthesis (yeast) PWY-7411
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Thumb
    a 1-acyl-sn-glycerol 3-phosphate + an acyl-[acyl-carrier protein] → a holo-[acyl-carrier protein] + a 1,2-diacyl-sn-glycerol 3-phosphate
    ReactionCard
    PAMDB120416 → PAMDB120398
    1-palmitoylglycerol 3-phosphate → dipalmitoyl phosphatidate
    ReactionCard
    Saturated-2-Lysophosphatidates → 2-3-4-Saturated-L-Phosphatidates
    Saturated-2-Lysophosphatidates → 2-3-4-Saturated-L-Phosphatidates
    ReactionCard
    PAMDB120317+PAMDB110389 → PAMDB120513+PAMDB110248
    1-oleyl-2-lyso-phosphatidate + oleoyl-CoA → 1-18:1-2-18:1-phosphatidate + coenzyme A
    ReactionCard
    Complex Reactions: Not Available
    Transports:
    Metabolites:
    PAMDB IDNameView
    PAMDB0015824-Amino-4-deoxy-L-arabinose modified core oligosaccharide lipid AMetaboCard
    PAMDB000148Adenosine triphosphateMetaboCard
    PAMDB000345ADPMetaboCard
    PAMDB001633Hydrogen ionMetaboCard
    PAMDB001643KDO(2)-lipid IV(A)MetaboCard
    PAMDB001447KDO2-Lipid AMetaboCard
    PAMDB000383PhosphateMetaboCard
    PAMDB001750Phosphoethanolamine KDO(2)-lipid (A)MetaboCard
    PAMDB000142WaterMetaboCard
    GO Classification:
    Component
    cell part
    periplasmic space
    Function
    binding
    lipopolysaccharide binding
    Process
    carbohydrate transport
    establishment of localization
    lipopolysaccharide transport
    polysaccharide transport
    transport
    Gene Properties
    Locus tag: PA0005
    Strand: -
    Entrez Gene ID: 877576
    Accession: NP_064725.1
    GI: 15595203
    Sequence start: 7018
    Sequence End: 7791
    Sequence Length: 773
    Gene Sequence: 
    >PA0005
ATGTCGACAGTGCAGGCCATCAGAACCGTCCTCTTTTACCTGCTGCTGTCCGCCAGCGCGTTCGTCTGGGGCACCCTCAGCTTCTTCATCGCGCCGATCCTGCCGTTCCGCGCCCGCTACCGCTTCGTGGTACAGAACTGGTGCCGCTTCGCGATCTGGCTGACCCGCGTGGTCGCCGGCATCCGCTACGAGGTGCGCGGACTGGAGAACATCCCGGAAAAGCCCTGCGTGATCCTCTCCAAGCACCAGAGCACCTGGGAAACCTTCTTCCTCTCCGGCTTCTTCGAGCCACTCAGCCAGGTACTCAAGCGCGAGCTGCTCTACGTGCCGTTCTTCGGCTGGGCCCTGGCCCTGCTCAAGCCCATCGCCATCGACCGCAGCCAGCCCAAGCTGGCCCTCAAGCAACTGGCCAAGCAGGGCGACGAGTGCCTGAAGAAAGGCGCCTGGGTGCTGATCTTCCCGGAAGGCACGCGTATTCCGGTGGGGCAGATGGGCAAGTTCTCCCGCGGCGGCACCGCCCTGGCGGTCAACGCCGGGCTACCGGTACTGCCGATCGCCCACAACGCCGGGCAGTATTGGCCCAAGGCCGGCTGGGCCAAGTACCCGGGCACCATCCAGGTGGTGATCGGCCCGGCCATGCACGCCGAAGGCGAAGGCCCGCGCGCCATCGCCGAGCTAAACCAGCGCGCCGAAGCCTGGGTCAGCGAGACCATGGCCGAGATCAGCCCCATCCAGCAGCGGGTCAGCCATCCGGAGCCGTCGGTGGTCTCGTGA
    Protein Properties
    Protein Residues: 257
    Protein Molecular Weight: 28.7 kDa
    Protein Theoretical pI: 10.23
    Hydropathicity (GRAVY score): 0.182
    Charge at pH 7 (predicted): 10.86
    Protein Sequence: 
    >PA0005
MSTVQAIRTVLFYLLLSASAFVWGTLSFFIAPILPFRARYRFVVQNWCRFAIWLTRVVAGIRYEVRGLENIPEKPCVILSKHQSTWETFFLSGFFEPLSQVLKRELLYVPFFGWALALLKPIAIDRSQPKLALKQLAKQGDECLKKGAWVLIFPEGTRIPVGQMGKFSRGGTALAVNAGLPVLPIAHNAGQYWPKAGWAKYPGTIQVVIGPAMHAEGEGPRAIAELNQRAEAWVSETMAEISPIQQRVSHPEPSVVS
    References
    External Links:
    Resource Link
    Genome ID: PA0005
    Entrez Gene ID: 877576
    NCBI Protein ID: 15595203
    General Reference: PaperBLAST - Find papers about PA0005 and its homologs