a 2'-deoxyribonucleoside 5'-diphosphate + an oxidized thioredoxin + a 2'-deoxyribonucleoside 5'-diphosphate + H2O = a ribonucleoside diphosphate + a reduced thioredoxin + a ribonucleoside diphosphate
a PchF NRPS protein loaded with L-cysteine + a PchE NRPS protein loaded with hydroxyphenyl-thiazoline → a [PchF protein]-hydroxyphenyl-4,2-bis-thiazoline + a PchE non-ribosomal peptide synthase protein + H2O + H+