P. aeruginosa Metabolome Database: Search Results for proteins

Succinate dehydrogenase iron-sulfur subunit

Gene Name: sdhB

Locus: PA1584

General function: Involved in electron carrier activity

Specific Function:
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth

PA1585

2-oxoglutarate dehydrogenase E1 component

Gene Name: sucA

Locus: PA1585

General function: Involved in oxoglutarate dehydrogenase (succinyl-transferring) activity

Specific Function:
The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components:2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)

PA1586

Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex

Gene Name: sucB

Locus: PA1586

General function: Involved in transferase activity, transferring acyl groups

Specific Function:
The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components:2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)

PA1587

dihydrolipoamide dehydrogenase Lpd LPD-GLC, L-factor for glycine oxidation system; dihydrolipoamide dehydrogenase (E3 subunit)

Gene Name: lpd

Locus: PA1587

General function: oxidation-reduction process, cell redox homeostasis, pathogenesis, evasion or tolerance of host immune response

Specific Function:
oxidoreductase activity, flavin adenine dinucleotide binding, oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor, dihydrolipoyl dehydrogenase activity

PA1588

Succinyl-CoA ligase [ADP-forming] subunit beta

Gene Name: sucC

Locus: PA1588

General function: Involved in ATP binding

Specific Function:
ATP + succinate + CoA = ADP + phosphate + succinyl-CoA

PA1589

Succinyl-CoA ligase [ADP-forming] subunit alpha

Gene Name: sucD

Locus: PA1589

General function: Involved in catalytic activity

Specific Function:
ATP + succinate + CoA = ADP + phosphate + succinyl-CoA