Reaction 21952

Reaction Details
Reaction: Thumb
3-methyl-2-oxobutanoate + an [apo BCAA dehydrogenase E2 protein] N6-lipoyl-L-lysine + H+ = an [apo BCAA dehydrogenase E2 protein] N6-S-[2-methylpropanoyl]dihydrolipoyl-L-lysine + CO2
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:1.2.4.4-RXN
References:
  • Bowden JA, Connelly JL (1968). "Branched chain alpha-keto acid metabolism. II. Evidence for the common identity of alpha-ketoisocaproic acid and alpha-keto-beta-methyl-valeric acid dehydrogenases." J Biol Chem 243(12);3526-31. PMID: 5656388