branched-chain alpha-keto acid dehydrogenase (lipoamide component) dihydrolipoamide branched chain transacylase (PA2249)

Identification
Name: branched-chain alpha-keto acid dehydrogenase (lipoamide component) dihydrolipoamide branched chain transacylase
Synonyms: Not Available
Gene Name: bkdB
Enzyme Class: Not Available
Biological Properties
General Function: cellular amino acid metabolic process, oxoacid metabolic process, metabolic process
Specific Function: transferase activity, transferring acyl groups
Cellular Location: Cytoplasmic
KEGG Pathways:
  • 2-oxoisovalerate decarboxylation to isobutanoyl-CoA PWY-5046
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Thumb
    3-methyl-2-oxobutanoate + an [apo BCAA dehydrogenase E2 protein] N6-lipoyl-L-lysine + H+ = an [apo BCAA dehydrogenase E2 protein] N6-S-[2-methylpropanoyl]dihydrolipoyl-L-lysine + CO2
    ReactionCard
    PAMDB000605+BCAA-dehydrogenase-lipoyl → BCAA-dehydrogenase-2MB-DH-lipoyl+PAMDB000568
    2-Keto-3-methyl-valerate + BCAA-dehydrogenase-lipoyl → BCAA-dehydrogenase-2MB-DH-lipoyl + Carbon dioxide
    ReactionCard
    Complex Reactions: Not Available
    Transports: Not Available
    Metabolites: Not Available
    GO Classification:
    Function
    transferase activity, transferring acyl groups
    Process
    cellular amino acid metabolic process
    oxoacid metabolic process
    metabolic process
    Gene Properties
    Locus tag: PA2249
    Strand: +
    Entrez Gene ID: 880679
    Accession: NP_250939.1
    GI: 15597445
    Sequence start: 2475495
    Sequence End: 2476781
    Sequence Length: 1286
    Gene Sequence: 
    >PA2249
ATGGGTACCCATGTGATCAAGATGCCGGACATCGGGGAAGGCATCGCCGAGGTCGAACTGGTGGAGTGGCATGTCCAGGTCGGCGACTCGGTCAATGAAGACCAGGTCCTCGCCGAGGTGATGACCGACAAGGCCACGGTGGAGATTCCCTCGCCGGTGGCCGGACGCATCCTCGCCCTCGGCGGCCAGCCGGGCCAGGTGATGGCGGTGGGCGGCGAACTGATCCGCCTGGAGGTGGAAGGCGCCGGCAACCTCGCCGAGAGTCCGGCCGCGGCGACGCCGGCCGCGCCCGTCGCCGCCACCCCGGAGAAACCGAAGGAAGCCCCGGTCGCGGCGCCGAAAGCCGCCGCCGAAGCGCCGCGCGCCTTGCGCGACAGCGAGGCGCCACGGCAGCGGCGCCAGCCCGGCGAACGCCCGCTGGCCTCCCCCGCGGTGCGCCAGCGCGCCCGCGACCTGGGCATCGAGTTGCAGTTCGTGCAGGGCAGCGGTCCCGCCGGACGCGTCCTCCACGAGGACCTCGATGCCTACCTGACCCAGGATGGCAGCGTCGCGCGCAGCGGCGGCGCCGCGCAGGGGTATGCCGAGCGACACGACGAACAGGCGGTGCCGGTGATCGGCCTGCGTCGCAAGATCGCCCAGAAGATGCAGGACGCCAAGCGACGCATCCCGCATTTCAGCTATGTCGAGGAAATCGACGTCACCGATCTGGAAGCCCTGCGCGCCCATCTCAACCAGAAATGGGGTGGCCAGCGCGGCAAGCTGACCCTGCTGCCGTTCCTGGTCCGCGCCATGGTCGTGGCGCTGCGCGACTTCCCGCAGTTGAACGCGCGCTACGACGACGAGGCCGAGGTGGTCACCCGCTACGGCGCGGTGCACGTCGGCATCGCCACCCAGAGCGACAACGGCCTGATGGTGCCGGTGCTGCGCCACGCCGAATCGCGCGACCTCTGGGGCAACGCCAGCGAAGTGGCGCGCCTGGCCGAAGCCGCACGCAGCGGCAAGGCGCAACGCCAGGAGCTGTCCGGCTCGACCATCACCCTGAGCAGCCTCGGCGTGCTCGGCGGGATCGTCAGCACACCGGTGATCAACCATCCGGAGGTGGCCATCGTCGGCGTCAACCGCATCGTCGAGCGACCGATGGTGGTCGGCGGCAACATCGTCGTGCGCAAGATGATGAACCTCTCCTCCTCCTTCGACCACCGGGTGGTCGACGGGATGGACGCGGCGGCCTTCATCCAGGCCGTGCGCGGCCTGCTCGAACATCCCGCCACCCTGTTCCTGGAGTAA
    Protein Properties
    Protein Residues: 428
    Protein Molecular Weight: 45.8 kDa
    Protein Theoretical pI: 6.15
    Hydropathicity (GRAVY score): -0.138
    Charge at pH 7 (predicted): -5.33
    Protein Sequence: 
    >PA2249
MGTHVIKMPDIGEGIAEVELVEWHVQVGDSVNEDQVLAEVMTDKATVEIPSPVAGRILALGGQPGQVMAVGGELIRLEVEGAGNLAESPAAATPAAPVAATPEKPKEAPVAAPKAAAEAPRALRDSEAPRQRRQPGERPLASPAVRQRARDLGIELQFVQGSGPAGRVLHEDLDAYLTQDGSVARSGGAAQGYAERHDEQAVPVIGLRRKIAQKMQDAKRRIPHFSYVEEIDVTDLEALRAHLNQKWGGQRGKLTLLPFLVRAMVVALRDFPQLNARYDDEAEVVTRYGAVHVGIATQSDNGLMVPVLRHAESRDLWGNASEVARLAEAARSGKAQRQELSGSTITLSSLGVLGGIVSTPVINHPEVAIVGVNRIVERPMVVGGNIVVRKMMNLSSSFDHRVVDGMDAAAFIQAVRGLLEHPATLFLE
    References
    External Links:
    Resource Link
    Genome ID: PA2249
    Entrez Gene ID: 880679
    NCBI Protein ID: 15597445
    General Reference: PaperBLAST - Find papers about PA2249 and its homologs