Reaction Details
Reaction: Thumb
precorrin-2 + S-adenosyl-L-methionine → S-adenosyl-L-homocysteine + precorrin-3A + H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:2.1.1.130-RXN
References:
  • Debussche L, Thibaut D, Cameron B, Crouzet J, Blanche F (1993). "Biosynthesis of the corrin macrocycle of coenzyme B12 in Pseudomonas denitrificans." J Bacteriol 175(22);7430-40. PMID: 8226690
  • Roessner CA, Warren MJ, Santander PJ, Atshaves BP, Ozaki S, Stolowich NJ, Iida K, Scott AI (1992). "Expression of 9 Salmonella typhimurium enzymes for cobinamide synthesis. Identification of the 11-methyl and 20-methyl transferases of corrin biosynthesis." FEBS Lett 301(1);73-8. PMID: 1451790
  • Roessner CA, Spencer JB, Ozaki S, Min C, Atshaves BP, Nayar P, Anousis N, Stolowich NJ, Holderman MT, Scott AI (1995). "Overexpression in Escherichia coli of 12 vitamin B12 biosynthetic enzymes." Protein Expr Purif 6(2);155-63. PMID: 7606163