precorrin-2 methyltransferase CobI (PA2904)

Identification
Name: precorrin-2 methyltransferase CobI
Synonyms: cbiL
Gene Name: cobI
Enzyme Class: Not Available
Biological Properties
General Function: cofactor biosynthetic process, cobalamin biosynthetic process, metabolic process
Specific Function: ferredoxin-NADP+ reductase activity, precorrin-2 C20-methyltransferase activity, S-adenosylmethionine-dependent methyltransferase activity, methyltransferase activity
Cellular Location: Cytoplasmic
KEGG Pathways:
  • adenosylcobalamin biosynthesis II (late cobalt incorporation) P381-PWY
  • cob(II)yrinate a,c-diamide biosynthesis II (late cobalt incorporation) PWY-7376
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Thumb
    precorrin-2 + S-adenosyl-L-methionine → S-adenosyl-L-homocysteine + precorrin-3A + H+
    ReactionCard
    Complex Reactions: Not Available
    Transports: Not Available
    Metabolites: Not Available
    GO Classification:
    Function
    ferredoxin-NADP+ reductase activity
    precorrin-2 C20-methyltransferase activity
    S-adenosylmethionine-dependent methyltransferase activity
    methyltransferase activity
    Process
    cofactor biosynthetic process
    cobalamin biosynthetic process
    metabolic process
    Gene Properties
    Locus tag: PA2904
    Strand: -
    Entrez Gene ID: 882688
    Accession: NP_251594.1
    GI: 15598100
    Sequence start: 3258353
    Sequence End: 3259105
    Sequence Length: 752
    Gene Sequence: 
    >PA2904
ATGATGAGTGTCGTGAAGGGCCGCCTGCTGGGCCTGGGCGTCGGGCCCGGCGATCCCGAACTGATCACCCTCAAGGCCCTGCGCCTGCTGCGCGCGGCGCCGGTGGTCGGCTATTTCGTGGCCAAGGGCAAGAAGGGCAACGCCTTCGGCATCATCGAGGCGCACCTGGACCAGGCCCAGGTGCGCCTGCCGCTGGTCTATCCGGTGACCACCGAGAAGCTGGAACCGCCGCTGTGCTACGAGACCATCATCAGCGATTTCTACGACACCGCCGCCGAACAGCTGGCCGCGCACCTGGACGCCGGCCGCGACGTGGCGGTGATCTGCGAGGGCGACCCGTTCTTCTACGGTTCCTACATGTACCTGCACGACCGCCTGGCGACGCGCTACGAAAGCGAAGTGGTGCCTGGCGTCTGCTCGATGCTCGGCGGCGCGGCGGTGCTCGGTGCGCCGCTGGTGTACCGCAACCAGAGCCTCTCGGTGCTCTCCGGAGTGCTGCCCGAGGAGGAGTTGCGCCGGCGCCTGGCGGATGCCGACGCGGCGGTGGTGATGAAGCTCGGCCGCAATTTCGACAAGGTCCGCCGCGTGCTGGTCGAGCTTGGCCTCGAGCGCCGCGCGCTGTACGTCGAGCGGGCGACCATGGCCAACCAGCGGATCGTGCCGTTGGAACGGGTGGAGCCGATGGCCTCGCCGTACTTCTCGCTGATCGTCGTTCCCGGCGACAAGTGGCAGGGAGGGGCCGGCGGTGAGTGA
    Protein Properties
    Protein Residues: 250
    Protein Molecular Weight: 27.3 kDa
    Protein Theoretical pI: 6.29
    Hydropathicity (GRAVY score): 0.122
    Charge at pH 7 (predicted): -1.37
    Protein Sequence: 
    >PA2904
MMSVVKGRLLGLGVGPGDPELITLKALRLLRAAPVVGYFVAKGKKGNAFGIIEAHLDQAQVRLPLVYPVTTEKLEPPLCYETIISDFYDTAAEQLAAHLDAGRDVAVICEGDPFFYGSYMYLHDRLATRYESEVVPGVCSMLGGAAVLGAPLVYRNQSLSVLSGVLPEEELRRRLADADAAVVMKLGRNFDKVRRVLVELGLERRALYVERATMANQRIVPLERVEPMASPYFSLIVVPGDKWQGGAGGE
    References
    External Links:
    Resource Link
    Genome ID: PA2904
    Entrez Gene ID: 882688
    NCBI Protein ID: 15598100
    General Reference: PaperBLAST - Find papers about PA2904 and its homologs