Reaction 21690

Reaction Details
Reaction: Thumb
a DNA containing ring-opened 7-methylguanine + H2O → 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine + a DNA containing an apurinic site
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:3.2.2.23-RXN
References:
  • Boiteux S, O'Connor TR, Laval J (1987). "Formamidopyrimidine-DNA glycosylase of Escherichia coli: cloning and sequencing of the fpg structural gene and overproduction of the protein." EMBO J 6(10);3177-83. PMID: 3319582