Identification
Name: formamidopyrimidine-DNA glycosylase
Synonyms: fpg
Gene Name: mutY
Enzyme Class: Not Available
Biological Properties
General Function: DNA repair, DNA repair, nucleotide-excision repair, base-excision repair
Specific Function: hydrolase activity, nucleic acid binding, catalytic activity, DNA binding, hydrolase activity, hydrolyzing N-glycosyl compounds, zinc ion binding, DNA-(apurinic or apyrimidinic site) lyase activity, damaged DNA binding
Cellular Location: Cytoplasmic
KEGG Pathways:
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Thumb
    a DNA containing ring-opened 7-methylguanine + H2O → 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine + a DNA containing an apurinic site
    ReactionCard
    Complex Reactions: Not Available
    Transports: Not Available
    Metabolites: Not Available
    GO Classification:
    Function
    hydrolase activity
    nucleic acid binding
    catalytic activity
    DNA binding
    hydrolase activity, hydrolyzing N-glycosyl compounds
    zinc ion binding
    DNA-(apurinic or apyrimidinic site) lyase activity
    damaged DNA binding
    Process
    DNA repair
    DNA repair
    nucleotide-excision repair
    base-excision repair
    Gene Properties
    Locus tag: PA0357
    Strand: +
    Entrez Gene ID: 879307
    Accession: NP_249048.1
    GI: 15595554
    Sequence start: 401131
    Sequence End: 401943
    Sequence Length: 812
    Gene Sequence:
    >PA0357
    ATGCCCGAACTACCCGAAGTCGAAACCACCCGCCGGGGCATCGCCCCCTACCTCGAAGGCCAGCGCGTCGAGCGCGTGATCGTGCGCGAGCGGCGCCTGCGCTGGCCGATTCCCGAAGACCTGGACGTGCGCCTGTCCGGACAACGCATCGTCAGCGTCGAGCGCCGCGCCAAGTACCTGCTGCTGGGCGCCGAGGCCGGTACGCTGATCAGCCACCTGGGCATGTCCGGCAGCCTGAGGCTGGTGGAGAGCGGCACCCCGGCCAGTCGCCACGAGCACGTCGACATCGAGCTGGCCTCGGGCATGGCCCTGCGCTACACCGATCCGCGGCGCTTCGGCGCCATGCTCTGGAGCCTGGCGCCACTGGAACACGAGTTGCTGCGCAACCTCGGCCCGGAACCGCTGACCGACGCTTTCGCCGGCCAGCGTCTGTTCGAGCTGTCGCGCGGGCGGAGCATGGCGGTCAAGCCGTTCATCATGGACAACGCGGTGGTGGTCGGGGTCGGCAACATCTACGCCAGCGAAGCGCTGTTCGCCGCCGGCATCGATCCGCGCAAGCCCGCCGGGAGCATCTCCAAGGCGCGCTACCTGCGCCTGGCGGAGGAGATCAAGCGGATCCTGGCGATCGCCATCGAGCGCGGCGGCACCACCCTGCGCGATTTCGTCGGCGGCGACGGCCAGCCCGGTTACTTCCAGCAGGAATTGTTCGTCTATGGCCGTGGCGGGGAGTTCTGCAAGGTCTGCGGCAGCACCCTGCGCGAGATCCGCCTAGGCCAGCGCGCCAGCGTGTACTGCCCGCGCTGCCAACGCTGA
    Protein Properties
    Protein Residues: 270
    Protein Molecular Weight: 30 kDa
    Protein Theoretical pI: 9.61
    Hydropathicity (GRAVY score): -0.196
    Charge at pH 7 (predicted): 7.84
    Protein Sequence:
    >PA0357
    MPELPEVETTRRGIAPYLEGQRVERVIVRERRLRWPIPEDLDVRLSGQRIVSVERRAKYLLLGAEAGTLISHLGMSGSLRLVESGTPASRHEHVDIELASGMALRYTDPRRFGAMLWSLAPLEHELLRNLGPEPLTDAFAGQRLFELSRGRSMAVKPFIMDNAVVVGVGNIYASEALFAAGIDPRKPAGSISKARYLRLAEEIKRILAIAIERGGTTLRDFVGGDGQPGYFQQELFVYGRGGEFCKVCGSTLREIRLGQRASVYCPRCQR
    References
    External Links:
    Resource Link
    Genome ID: PA0357
    Entrez Gene ID: 879307
    NCBI Protein ID: 15595554
    General Reference: PaperBLAST - Find papers about PA0357 and its homologs