Identification |
Name: |
formamidopyrimidine-DNA glycosylase |
Synonyms: |
fpg |
Gene Name: |
mutY |
Enzyme Class: |
Not Available |
Biological Properties |
General Function: |
DNA repair, DNA repair, nucleotide-excision repair, base-excision repair |
Specific Function: |
hydrolase activity, nucleic acid binding, catalytic activity, DNA binding, hydrolase activity, hydrolyzing N-glycosyl compounds, zinc ion binding, DNA-(apurinic or apyrimidinic site) lyase activity, damaged DNA binding |
Cellular Location: |
Cytoplasmic |
KEGG Pathways: |
|
KEGG Reactions: |
Not Available |
SMPDB Reactions: |
Not Available |
PseudoCyc/BioCyc Reactions: |
| a DNA containing ring-opened 7-methylguanine + H 2O → 2,6-diamino-4-hydroxy-5-( N-methyl)formamidopyrimidine + a DNA containing an apurinic site ReactionCard |
|
Complex Reactions: |
Not Available |
Transports: |
Not Available |
Metabolites: |
Not Available |
GO Classification: |
Function |
---|
hydrolase activity | nucleic acid binding | catalytic activity | DNA binding | hydrolase activity, hydrolyzing N-glycosyl compounds | zinc ion binding | DNA-(apurinic or apyrimidinic site) lyase activity | damaged DNA binding | Process |
---|
DNA repair | DNA repair | nucleotide-excision repair | base-excision repair |
|
Gene Properties |
Locus tag: |
PA0357 |
Strand: |
+ |
Entrez Gene ID: |
879307 |
Accession: |
NP_249048.1 |
GI: |
15595554 |
Sequence start: |
401131 |
Sequence End: |
401943 |
Sequence Length: |
812 |
Gene Sequence: |
>PA0357
ATGCCCGAACTACCCGAAGTCGAAACCACCCGCCGGGGCATCGCCCCCTACCTCGAAGGCCAGCGCGTCGAGCGCGTGATCGTGCGCGAGCGGCGCCTGCGCTGGCCGATTCCCGAAGACCTGGACGTGCGCCTGTCCGGACAACGCATCGTCAGCGTCGAGCGCCGCGCCAAGTACCTGCTGCTGGGCGCCGAGGCCGGTACGCTGATCAGCCACCTGGGCATGTCCGGCAGCCTGAGGCTGGTGGAGAGCGGCACCCCGGCCAGTCGCCACGAGCACGTCGACATCGAGCTGGCCTCGGGCATGGCCCTGCGCTACACCGATCCGCGGCGCTTCGGCGCCATGCTCTGGAGCCTGGCGCCACTGGAACACGAGTTGCTGCGCAACCTCGGCCCGGAACCGCTGACCGACGCTTTCGCCGGCCAGCGTCTGTTCGAGCTGTCGCGCGGGCGGAGCATGGCGGTCAAGCCGTTCATCATGGACAACGCGGTGGTGGTCGGGGTCGGCAACATCTACGCCAGCGAAGCGCTGTTCGCCGCCGGCATCGATCCGCGCAAGCCCGCCGGGAGCATCTCCAAGGCGCGCTACCTGCGCCTGGCGGAGGAGATCAAGCGGATCCTGGCGATCGCCATCGAGCGCGGCGGCACCACCCTGCGCGATTTCGTCGGCGGCGACGGCCAGCCCGGTTACTTCCAGCAGGAATTGTTCGTCTATGGCCGTGGCGGGGAGTTCTGCAAGGTCTGCGGCAGCACCCTGCGCGAGATCCGCCTAGGCCAGCGCGCCAGCGTGTACTGCCCGCGCTGCCAACGCTGA |
Protein Properties |
Protein Residues: |
270 |
Protein Molecular Weight: |
30 kDa |
Protein Theoretical pI: |
9.61 |
Hydropathicity (GRAVY score): |
-0.196 |
Charge at pH 7 (predicted): |
7.84 |
Protein Sequence: |
>PA0357
MPELPEVETTRRGIAPYLEGQRVERVIVRERRLRWPIPEDLDVRLSGQRIVSVERRAKYLLLGAEAGTLISHLGMSGSLRLVESGTPASRHEHVDIELASGMALRYTDPRRFGAMLWSLAPLEHELLRNLGPEPLTDAFAGQRLFELSRGRSMAVKPFIMDNAVVVGVGNIYASEALFAAGIDPRKPAGSISKARYLRLAEEIKRILAIAIERGGTTLRDFVGGDGQPGYFQQELFVYGRGGEFCKVCGSTLREIRLGQRASVYCPRCQR |
References |
External Links: |
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General Reference: |
PaperBLAST - Find papers about PA0357 and its homologs
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