Reaction 21590

Reaction Details
Reaction: Thumb
α-D-glucopyranose 1-phosphate + dTTP + H+ → dTDP-α-D-glucose + diphosphate
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:DTDPGLUCOSEPP-RXN
References:
  • KORNFELD S, GLASER L (1961). "The enzymic synthesis of thymidine-linked sugars. I. Thymidine diphosphate glucose." J Biol Chem 236;1791-4. PMID: 13753209
  • PAZUR JH, SHUEY EW (1961). "The enzymatic synthesis of thymidine diphosphate glucose and its conversion to thymidine diphosphate rhamnose." J Biol Chem 236;1780-5. PMID: 13733719
  • Zuccotti S, Zanardi D, Rosano C, Sturla L, Tonetti M, Bolognesi M (2001). "Kinetic and crystallographic analyses support a sequential-ordered bi bi catalytic mechanism for Escherichia coli glucose-1-phosphate thymidylyltransferase." J Mol Biol 313(4);831-43. PMID: 11697907