Reaction Details
Reaction: Thumb
O-acetyl-L-serine + hydrogen sulfide → L-cysteine + acetate + H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:ACSERLY-RXN
References:
  • Becker MA, Kredich NM, Tomkins GM (1969). "The purification and characterization of O-acetylserine sulfhydrylase-A from Salmonella typhimurium." J Biol Chem 244(9);2418-27. PMID: 4891157
  • Bettati S, Benci S, Campanini B, Raboni S, Chirico G, Beretta S, Schnackerz KD, Hazlett TL, Gratton E, Mozzarelli A (2000). "Role of pyridoxal 5'-phosphate in the structural stabilization of O-acetylserine sulfhydrylase." J Biol Chem 275(51);40244-51. PMID: 10995767
  • Hara S, Payne MA, Schnackerz KD, Cook PF (1990). "A rapid purification procedure and computer-assisted sulfide ion selective electrode assay for O-acetylserine sulfhydrylase from Salmonella typhimurium." Protein Expr Purif 1(1);70-6. PMID: 2152186
  • Tai CH, Burkhard P, Gani D, Jenn T, Johnson C, Cook PF (2001). "Characterization of the allosteric anion-binding site of O-acetylserine sulfhydrylase." Biochemistry 40(25);7446-52. PMID: 11412097