Reaction Details
Reaction: Thumb
Fe2+ + protoporphyrin IX → ferroheme b + 2 H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:PROTOHEMEFERROCHELAT-RXN
References:
  • Bloomer JR, Hill HD, Morton KO, Anderson-Burnham LA, Straka JG (1987). "The enzyme defect in bovine protoporphyria. Studies with purified ferrochelatase." J Biol Chem 262(2);667-71. PMID: 3805002
  • PORRA RJ, JONES OT (1963). "Studies on ferrochelatase. 2. An in vestigation of the role offerrochelatase in the biosynthesis of various haem prosthetic groups." Biochem J 87;186-92. PMID: 13972329
  • PORRA RJ, JONES OT (1963). "Studies on ferrochelatase. 1. Assay and properties of ferrochelatase from a pig-liver mitochondrial extract." Biochem J 87;181-5. PMID: 13972328