Reaction 21485

Reaction Details
Reaction: Thumb
1-(5-phospho-β-D-ribosyl)-ATP + diphosphate ← ATP + 5-phospho-α-D-ribose 1-diphosphate + H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:ATPPHOSPHORIBOSYLTRANS-RXN
References:
  • AMES BN, MARTIN RG, GARRY BJ (1961). "The first step of histidine biosynthesis." J Biol Chem 236;2019-26. PMID: 13682989
  • Voll MJ, Appella E, Martin RG (1967). "Purification and composition studies of phosphoribosyladenosine triphosphate:pyrophosphate phosphoribosyltransferase, the first enzyme of histidine biosynthesis." J Biol Chem 242(8);1760-7. PMID: 5337591