Reaction Details
Reaction: Thumb
erythronate-4-phosphate + NAD+ → 2-oxo-3-hydroxy-4-phosphobutanoate + NADH + H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:ERYTHRON4PDEHYDROG-RXN
References:
  • Grant GA (1989). "A new family of 2-hydroxyacid dehydrogenases." Biochem Biophys Res Commun 165(3);1371-4. PMID: 2692566
  • Lam HM, Winkler ME (1990). "Metabolic relationships between pyridoxine (vitamin B6) and serine biosynthesis in Escherichia coli K-12." J Bacteriol 1990;172(11);6518-28. PMID: 2121717
  • Pease AJ, Roa BR, Luo W, Winkler ME (2002). "Positive growth rate-dependent regulation of the pdxA, ksgA, and pdxB genes of Escherichia coli K-12." J Bacteriol 184(5);1359-69. PMID: 11844765
  • Schoenlein PV, Roa BB, Winkler ME (1989). "Divergent transcription of pdxB and homology between the pdxB and serA gene products in Escherichia coli K-12." J Bacteriol 171(11);6084-92. PMID: 2681152
  • Zhao G, Winkler ME (1996). "A novel alpha-ketoglutarate reductase activity of the serA-encoded 3-phosphoglycerate dehydrogenase of Escherichia coli K-12 and its possible implications for human 2-hydroxyglutaric aciduria." J Bacteriol 1996;178(1);232-9. PMID: 8550422