Reaction 21328

Reaction Details
Reaction: Thumb
hydrogenobyrinate a,c-diamide + Co2+ + ATP + H2O → cob(II)yrinate a,c-diamide + ADP + phosphate + 3 H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:R342-RXN
References:
  • Debussche L, Couder M, Thibaut D, Cameron B, Crouzet J, Blanche F (1992). "Assay, purification, and characterization of cobaltochelatase, a unique complex enzyme catalyzing cobalt insertion in hydrogenobyrinic acid a,c-diamide during coenzyme B12 biosynthesis in Pseudomonas denitrificans." J Bacteriol 174(22);7445-51. PMID: 1429466
  • Warren MJ, Raux E, Schubert HL, Escalante-Semerena JC (2002). "The biosynthesis of adenosylcobalamin (vitamin B12)." Nat Prod Rep 19(4);390-412. PMID: 12195810