Identification
Name: cobalamin biosynthetic protein CobN
Synonyms: Not Available
Gene Name: cobN
Enzyme Class: Not Available
Biological Properties
General Function: cofactor biosynthetic process, cobalamin biosynthetic process, biosynthetic process
Specific Function: cobaltochelatase activity
Cellular Location: Cytoplasmic
KEGG Pathways:
  • adenosylcobalamin biosynthesis II (late cobalt incorporation) P381-PWY
  • cob(II)yrinate a,c-diamide biosynthesis II (late cobalt incorporation) PWY-7376
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Thumb
    hydrogenobyrinate a,c-diamide + Co2+ + ATP + H2O → cob(II)yrinate a,c-diamide + ADP + phosphate + 3 H+
    ReactionCard
    Complex Reactions: Not Available
    Transports: Not Available
    Metabolites: Not Available
    GO Classification:
    Function
    cobaltochelatase activity
    Process
    cofactor biosynthetic process
    cobalamin biosynthetic process
    biosynthetic process
    Gene Properties
    Locus tag: PA2944
    Strand: -
    Entrez Gene ID: 882831
    Accession: NP_251634.1
    GI: 15598140
    Sequence start: 3300615
    Sequence End: 3304361
    Sequence Length: 3746
    Gene Sequence:
    >PA2944
    ATGCACCTGTTGCGCACCCAACCCGGCGGCTTCGTTCCCGACGACGGCATCGCCCACCTGGCCCAGACTCCCGCCGAGCTGGTGATCCTCTGCAGCGGCGATTCGCACCTCGCATTGCTGGCCGAGGCCGCCCGTGCGCTGCCGGACGACTACCCGAGCCTGCGCCTGGCCAACCCCATGCAGTTGCAGAACCACGCCTCGGTGGACCTCTACGTCGAGGAAGTGCTGCGGCACGCGCGGGTGATCCTGCTTTCGCTGCACGGCGGCATCGGCTACTGGCGCTACGGCGTGGAGCAACTGGTGGCGCTGGCCGAGCGCGGCGCGCTGCTGATCCCGGTGCCCGGCGACGACCGCCCCGACCCGGAGCTGAGCGCCCTTGGCAACCTGCCGGCGGAGCAGGCCGAGCGCTTCTGGCAATACTTGCGCCAGGGCGGCCTGGAGAACGCCGGGCAGTTCTACCGCTGCCTGGCCAGCCAGTGCCTCGGCCGCGACTACGCCTGGCGCGAACCGCAGGCGCTGCCGCGGGTGGCACTGTTCCATCCACGGCATGCCGAGGCGACCCTGGAACACTGGCGTGCCGACTGGCAGGCCGGGCGTCCGGTGGTCGCGTTGCTGTTCTATCGCACCCACCTGCAGGCAGCCAACACCGCCTTCATCGCACGCTTCTGCGAACGCCTCGCGGCGCAGGGGCTCAACCCGTTGCCGATCGCGCTGGCCAGCCTCAAGGAAAGCGCCTGCCTGGCGCAGGTGGAAGACTGGCTGGAGCGCAGCGACGCCGCGCTGATCGTCAATACCACCGGTTTCGCCCAGTCCAATCCGGAGGCGCCCGAGTTGCGTCCGTTCCGTCGCGACGTGCCGGTATTGCAGGCGATCTGCTCGCTGGACAACCGCCCGCTCTGGCTGGACAACCCGCAAGGCCTGGGGCCGCGTGACCTGGCCATGCACGTGGCGCTGCCGGAGCTGGACGGGCGCATCGTCACCCGGCCGATCAGTTTCAAGGGCCTGGCCTGGCGCAGCGAACGCAGCGAGAGCGACGTGGTCTGCTATCTCGCCGACGACGAGCGCATGGATTTCGTCGCCGAACTGGCGCGGCGCTGGGCCGAGCTGGCGCGCAAGCCAAACGCGGAAAAACGGGTGGCGCTGGTGCTGGCCAACTACCCGACCCGCGATGGCCGGATCGGCAATGGCGTCGGCCTGGACACCCCGGCGGCGGCGCTGAACATCCTTCGTGCCCTGCGCCAGCAGGGCTATCCGGTCGACGGACTGCCCGCCAGCGGAACCGAGCTGATCCGCCAGTTGCTCGGCGGCGTCAGCAACGACCTGGAGCATCTCGACCTACGGCCCTGCGCCCAGAGCCTGGCGCTGGACGACTACCTGGCCTGCTTCGCACGCCTGCCGGAGCGCAATCGCCAGGCGGTGCTGGCGCGCTGGGGCGAGCCGCAACAGGACCCGATGTTCCGCGACGGACGGATGATGGTCGCCGGCCTGCGCTATGGCCTGACCTTCGTCGGCATCCAGCCGGCGCGCGGCTATCAGCTCGATCCGGCGGCGGTCTACCACGATCCCGACCTGGTGCCGCCGCACGGCTACCTGGCGTTCTACTTCTGGCTGCGCCACGCCTACCGCGCCGATGCCCTGCTGCACGTCGGCAAGCACGGTAACCTGGAATGGCTGCCGGGCAAGGGAGTCGGCCTGTCCGCCGAATGCTGGCCGGACGCGTTGCTCGGTCCGCTGCCGAACATCTATCCGTTCATCGTCAACGATCCGGGGGAGGGCGCCCAGGCCAAGCGCCGCACCCAGGCGGTGATCATCGACCACCTGATGCCGCCGCTGACCCGCGCCGAGAGCTACGGCCCGCTGCGCGACCTGGAGCGCCTGGCCGACGAGTTCTACGATGCCTCGCTGCTCGACCCGCGCCGCGCCGAACAGTTGCGCGGCGAGATTCTCGTCCTCCTGCGCGACAACCGTCTCGACCGCGAGATCGGCTTGCAGCTCAGCGACGATCCGGACAGCTGGCTGCCGCAGCTGGACGCCTATCTCTGCGACCTGAAGGAGTCGCAGATCCGCGACGGCCTGCATGTGTTCGGCGAGTCGCCGAGCGGGCGATTGCGCCTGGATACCCTGCTGGCGCTGCTGCGGGTTCCGCGCGGCGATGGCAAGGGCGCCAACGCCGGGTTGCTGAAGAGCCTGGCGGACGACCTTGGCCTGGGCTTCGATCCGCTGGCCTGCGACATGGGCGAGGCCTGGCAGGGCGCGCGGCCTGCCTGCCTGGAAGAGCGGGGCGGGGAGCCCTGGCGTACTCTCGGGGATACCCGCGAACGCCTGGAATTGCTGGCGTTGCACTGGATAGAACGCTGCCTGGGCGGCGAATCGCCGCCTGCCACCTGGCGTGCCAGCGGCGAGGTGTTGCGCGGCTTGTGCGAACAGGTGGCACCGACCCTGGACGCCTGTGGCGGGGCCGAGATCGACGGGCTGCTGGCAGCCCTCGAAGGGCGCTTCGTACCGGCCGGTCCGAGCGGCGCGCCGAGTCGCGGGCGACTCGACGTGCTGCCCACCGGACGCAACTTCTTCTCGGTGGACGTGCGCAACCTGCCGACCCCGACCGCCTGGCGCATCGGCTTCCAGTCGGCCAACCTGCTGCTCGAGCGTCACCTGCAGGAACATGGCGATCACCTGCGCCAGCTCGGCCTCTCGGTGTGGGGCACGGCGACCATGCGCACCGGCGGCGACGACATCGCCCAGGCCCTGGCCCTGCTCGGCGTGCGACCGGTCTGGCAGGCCGGCAGCCAGCGCGTCGCCGATTTCGAGATCCTCCCGGTCTCCCTGCTGGACCGCCCGCGGGTCGACGTGACGCTGCGGGTCTCCGGGTTCTTCCGCGACGCCTTCGCCAACCTGATCCGCCTGTTCGATGCGGCGGTGCAGGCGGTCGCCGAGCTGGACGAGGCGGAGGAGCTGAACCCGCTGGCCGCTCGCGTACGCCTGGAGCGCCAGCGCCTCGAGGCGCAGGGCACGGCGCCGGCGGAGGCGCGCCGGCAGGCCGGCTGGCGGATCTTCGGCGCCAAGCCGGGTGCCTACGGCGCCGGCGTGCAGGGCGCAATCGAAGAGCGGCTGTGGGAGACCCGCGCCGACCTTGCCGAGGTCTACCTGAACTGGGGCGGCTACGCCTACGGTGCCGCCGACGACGGCACGCCGGCGCGGGAACGCTTCGCCCAGCGCCTGGAACGCCTGCAGGCGGTGCTGCACAACCAGGACAACCGCGAGCACGACCTGCTCGATTCCAACGACTACTACCAGTTCCAGGGCGGCATGCTGGCGGCGGTGGAAACCCTGCGCGGCGCGCCGGTGGCCAGTTACCACGGCGACCACAGCCAGCCGGACAACCCGCGCATCCGCACGCTCAAGGAAGAACTCAACCGGGTGGTGCGGGCGCGGGCGGTGAATCCGAAGTGGATCGCCGGGATGAAGCGCCACGGCTACAAGGGCGCCTTCGAACTGGCGGCGACGGTGGACTACCTGTGCGCCTTCGATGCCACCAGCGAGCTGATCGACGACCACCAGTACGCGCTGCTGGCCGACGCCTACCTGCTCGACGCGGAGACCCGCGAGTTCGTCCGCCAGCACAATCCGCAAGCCTTGCGCGACATGGCCGAGCGCCTGGTGGAGGCGCAGCGGCGCGGGCTCTGGCAGGAGCCGGGGGCCTATCGCGAGGCCCTGGAGAACCTGCTGCTGGACGTCGAAGAGGAATAG
    Protein Properties
    Protein Residues: 1248
    Protein Molecular Weight: 138.5 kDa
    Protein Theoretical pI: 5.24
    Hydropathicity (GRAVY score): -0.277
    Charge at pH 7 (predicted): -31.19
    Protein Sequence:
    >PA2944
    MHLLRTQPGGFVPDDGIAHLAQTPAELVILCSGDSHLALLAEAARALPDDYPSLRLANPMQLQNHASVDLYVEEVLRHARVILLSLHGGIGYWRYGVEQLVALAERGALLIPVPGDDRPDPELSALGNLPAEQAERFWQYLRQGGLENAGQFYRCLASQCLGRDYAWREPQALPRVALFHPRHAEATLEHWRADWQAGRPVVALLFYRTHLQAANTAFIARFCERLAAQGLNPLPIALASLKESACLAQVEDWLERSDAALIVNTTGFAQSNPEAPELRPFRRDVPVLQAICSLDNRPLWLDNPQGLGPRDLAMHVALPELDGRIVTRPISFKGLAWRSERSESDVVCYLADDERMDFVAELARRWAELARKPNAEKRVALVLANYPTRDGRIGNGVGLDTPAAALNILRALRQQGYPVDGLPASGTELIRQLLGGVSNDLEHLDLRPCAQSLALDDYLACFARLPERNRQAVLARWGEPQQDPMFRDGRMMVAGLRYGLTFVGIQPARGYQLDPAAVYHDPDLVPPHGYLAFYFWLRHAYRADALLHVGKHGNLEWLPGKGVGLSAECWPDALLGPLPNIYPFIVNDPGEGAQAKRRTQAVIIDHLMPPLTRAESYGPLRDLERLADEFYDASLLDPRRAEQLRGEILVLLRDNRLDREIGLQLSDDPDSWLPQLDAYLCDLKESQIRDGLHVFGESPSGRLRLDTLLALLRVPRGDGKGANAGLLKSLADDLGLGFDPLACDMGEAWQGARPACLEERGGEPWRTLGDTRERLELLALHWIERCLGGESPPATWRASGEVLRGLCEQVAPTLDACGGAEIDGLLAALEGRFVPAGPSGAPSRGRLDVLPTGRNFFSVDVRNLPTPTAWRIGFQSANLLLERHLQEHGDHLRQLGLSVWGTATMRTGGDDIAQALALLGVRPVWQAGSQRVADFEILPVSLLDRPRVDVTLRVSGFFRDAFANLIRLFDAAVQAVAELDEAEELNPLAARVRLERQRLEAQGTAPAEARRQAGWRIFGAKPGAYGAGVQGAIEERLWETRADLAEVYLNWGGYAYGAADDGTPARERFAQRLERLQAVLHNQDNREHDLLDSNDYYQFQGGMLAAVETLRGAPVASYHGDHSQPDNPRIRTLKEELNRVVRARAVNPKWIAGMKRHGYKGAFELAATVDYLCAFDATSELIDDHQYALLADAYLLDAETREFVRQHNPQALRDMAERLVEAQRRGLWQEPGAYREALENLLLDVEEE
    References
    External Links:
    Resource Link
    Genome ID: PA2944
    Entrez Gene ID: 882831
    NCBI Protein ID: 15598140
    General Reference: PaperBLAST - Find papers about PA2944 and its homologs