Reaction 21150

Reaction Details
Reaction: Thumb
L-cysteine + L-glutamate + ATP → γ-L-glutamyl-L-cysteine + ADP + phosphate + H+
Enzymes:
External Links:
ResourceLink
PseudoCyc Reaction ID:GLUTCYSLIG-RXN
References:
  • Mackinnon CM, Carter PE, Smyth SJ, Dunbar B, Fothergill JE (1987). "Molecular cloning of cDNA for human complement component C1s. The complete amino acid sequence." Eur J Biochem 169(3);547-53. PMID: 3500856
  • MANDELES S, BLOCK K (1955). "Enzymatic synthesis of gamma-glutamylcysteine." J Biol Chem 214(2);639-46. PMID: 14381401
  • SNOKE JE, YANARI S, BLOCH K (1953). "Synthesis of glutathione from gamma-glutamylcysteine." J Biol Chem 201(2);573-86. PMID: 13061393